Self-evolving microstructured systems upon enzymatic catalysis

Chopineau, Joël; Lesieur, Sylviane; Carion-Taravella, Brigitte; Ollivon, Michel

doi:10.1016/s0300-9084(00)80010-3

Cited by 11 publications

(8 citation statements)

References 80 publications

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“…Gohon and Popot (2003) provide a brief, yet impressive overview over the concepts of using amphipathic peptides (peptidergents), polymers (amphipols), tripod detergents and hemifluorinated surfactants. PEG-grafted cholesterol acts as a detergent but can be enzymatically cleaved into cholesterol, a physiological membrane component, and water-soluble ethylene glycol, thus inducing reconstitution (Chopineau et al 1998).…”

Section: Applications and Biological Relevance Of Surfactant–membranementioning

confidence: 99%

Interactions of surfactants with lipid membranes

Heerklotz

2008

Quart. Rev. Biophys.

274

287

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Surfactants are surface-active, amphiphilic compounds that are water-soluble in the micro- to millimolar range, and self-assemble to form micelles or other aggregates above a critical concentration. This definition comprises synthetic detergents as well as amphiphilic peptides and lipopeptides, bile salts and many other compounds. This paper reviews the biophysics of the interactions of surfactants with membranes of insoluble, naturally occurring lipids. It discusses structural, thermodynamic and kinetic aspects of membrane-water partitioning, changes in membrane properties induced by surfactants, membrane solubilisation to micelles and other phases formed by lipid-surfactant systems. Each section defines and derives key parameters, mentions experimental methods for their measurement and compiles and discusses published data. Additionally, a brief overview is given of surfactant-like effects in biological systems, technical applications of surfactants that involve membrane interactions, and surfactant-based protocols to study biological membranes.

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Section: Applications and Biological Relevance Of Surfactant–membranementioning

confidence: 99%

Interactions of surfactants with lipid membranes

Heerklotz

2008

Quart. Rev. Biophys.

274

287

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“…Above their critical micellar concentration (cmc), which is in the range of 10 -10 M, phospholipids aggregate into a number of polymorphic phases (reviewed in Walde et al, 1990;Chopineau et al, 1998). Some of the most important aggregates are shown schematically in Figure 8.…”

Section: Suprastructures Of Phospholipidsmentioning

confidence: 99%

Phospholipases Used in Lipid Transformations

Ulbrich‐Hofmann

2000

Enzymes in Lipid Modification

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“…Surfactant lipids usually self-assemble in water and form a variety of lyotropic liquid crystalline (LC) phases. These binary systems attracted huge interest because of their biological relevance , and due to many possible applications as biomimetic material, , matrix for metal nanoparticle formation or crystallization of membrane proteins, protective matrices for proteins, and delivery systems in the fields of pharmaceutics, cosmetics, and food industry. , Lipid/water bulk phases possess a high interfacial area due to the space divided into two unconnected subspaces at the nanoscale: one hydrophilic and the other hydrophobic. Hence, they as reservoirs of active molecules of various hydrophobicity (i.e., drugs, aromas, proteins, or peptides) and their controlled release property have been extensively studied .…”

Section: Introductionmentioning

confidence: 99%

Influence of the Stabilizer Concentration on the Internal Liquid Crystalline Order and the Size of Oil-Loaded Monolinolein-Based Dispersions

et al. 2010

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The internal phase of monolinolein-based dispersions loaded with tetradecane or (R)-(+)-limonene was investigated as a function of the stabilizer content by small-angle X-ray scattering. Phase transitions at the colloidal scale were found in some of nanostructured aqueous dispersions by increasing the stabilizer content. For particles containing a bicontinuous cubic phase, a large increase of the stabilizer concentration promoted a liquid crystalline phase transition from the Pn3m to the Im3m cubic symmetry. The coexistence of both phases is observed in an intermediate stabilizer concentration range. For particles with an internal micellar cubic Fd3m symmetry, the internal structure changes in the isotropic fluid L(2) phase. In case of particles with an internal hexagonal phase (H(2) symmetry), the increasing amount of stabilizer did not alter the lattice parameter but decreased the size of the nanostructured domain. Moreover, we showed for hexagonal and emulsified micellar phase particles that the increase of the stabilizer content induced a strong decrease of the mean hydrodynamic size of the particles, allowing producing nanostructured lipid-based liquid crystalline particles down to a radius of 70 nm at the same energy input.

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Self-evolving microstructured systems upon enzymatic catalysis

Cited by 11 publications

References 80 publications

Interactions of surfactants with lipid membranes

Interactions of surfactants with lipid membranes

Phospholipases Used in Lipid Transformations

Influence of the Stabilizer Concentration on the Internal Liquid Crystalline Order and the Size of Oil-Loaded Monolinolein-Based Dispersions

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