Annotation. The introduction of martial law in Ukraine was the reason for the transition to a mixed form of educational activity and defined new challenges and opportunities for higher education institutions. Contrary to the complex realities of the time, the educational process continues in the country (in particular, in the Vinnytsia region) with a relative security situation. The article indicates a number of regulatory documents that govern the institution of higher education in the conduct of educational activities. The analysis of the concept of “blended learning” was also carried out, the main provisions in the organization of mixed education and its results were given on the example of students of 4-6 years at the National Pirogov Memorial Medical University, Vinnytsya. It was determined that the mixed form of education is a harmonious combination of classroom and distance-interactive work of education seekers using information and digital technologies. The advantages of using blended learning during the training of medical students are indicated, in particular, its ability to adapt and multifunctionality. This form of education had a positive effect on the motivation of future medical students and the formation of their competencies. The main online platforms and digital learning tools used during the implementation of blended learning in the educational process of medical institutions of higher education are highlighted, in particular: distance learning platforms Moodle and Microsoft Teams, online communication platforms Viber, Telegram, Messenger. It will be important to adapt the educational process in the conditions of war and to promote those measures aimed at reviving education in the post-war period, as well as increasing the possibilities of digitization in the country.