Self-assembly TiO2 nanosheets as a SALDI-TOF-MS matrix for high-throughput identification of polyfluorinated compounds in water samples

Porous TiO2 Film Immobilized with Gold Nanoparticles for Dual-Polarity SALDI MS Detection and Imaging

“…2,29 Additionally, compared with silver and gold nanoparticles (AuNPs), TiO 2 is cost-effective and shows excellent stability in an ambient environment. 30 Various TiO 2 materials such as nanoparticles, 31 nanoflakes, 32 nanosheets, 33 nanowires, 34 films, 35 and monoliths 36 have been used as matrixes in the laser desorption/ionization (LDI) MS profiling and imaging of small molecules in different samples.…”

“…Several studies have shown that the DI of analytes from the TiO 2 -based SALDI substrate is most likely initiated by laser-induced thermal desorption and nonthermal laser desorption induced by electron transitions because of the occurrence of a filled valence band and empty conduction band in n-type TiO 2 . , Additionally, compared with silver and gold nanoparticles (AuNPs), TiO 2 is cost-effective and shows excellent stability in an ambient environment . Various TiO 2 materials such as nanoparticles, nanoflakes, nanosheets, nanowires, films, and monoliths have been used as matrixes in the laser desorption/ionization (LDI) MS profiling and imaging of small molecules in different samples.…”

Hydrothermal alkaline defluorination rate of perfluorocarboxylic acids (PFCAs)

“…3,4 However, because of their extreme persistence and bioaccumulation, PFCAs are also recognized as global pollutants. 5,6 PFASs can cause serious damage to human health, including endocrine disruption, retarded physical development, and cancer. 7,8 Since the human health risks of pollutants have become an increasing concern over the past decade, 9 perfluorooctanoic sulfonic acid (PFOS) and its precursors (perfluorohexanesulfonic acid (PFHxS), perfluorooctanoic acid (PFOA), and PFASs containing 9 to 14 carbon chains) have been banned or regulated by international regulations, such as the Stockholm Convention and the European REACH Regulation, and by regulatory agencies, such as the United States Environmental Protection Agency (US EPA).…”

Rapid detection of perfluorinated sulfonic acids through preconcentration by bubble bursting and surface‐assisted laser desorption/ionization

“…20 SALDI involves binding silver nanoparticles (AgNPs) to biomolecules such as amino acids, cholesterol, fatty acids, and triacylglycerol (TAG) 21,22 as well as the use of gold nanoparticles for metabolic fingerprinting in clinical diagnosis, 23 mercury telluride nanomaterials (HgTe) for glycoconjugate detection, 24 and titanium dioxide for PFOS quantitative analysis. 25 Various nanomaterials, which are highly selective in signal enhancement, are suitable for detecting various analytes. Because silver nanoplates (AgNPts) 26 selectively enhance the detection of compounds with a sulfate group, they are used as SALDI matrices for PFS analysis.…”

“…Nanomaterials can be used as assisting materials for MALDI; this modified method is called surface‐assisted laser desorption/ionization (SALDI) and is associated with more homogenous sample morphology and increased reproducibility 20 . SALDI involves binding silver nanoparticles (AgNPs) to biomolecules such as amino acids, cholesterol, fatty acids, and triacylglycerol (TAG) 21,22 as well as the use of gold nanoparticles for metabolic fingerprinting in clinical diagnosis, 23 mercury telluride nanomaterials (HgTe) for glycoconjugate detection, 24 and titanium dioxide for PFOS quantitative analysis 25 . Various nanomaterials, which are highly selective in signal enhancement, are suitable for detecting various analytes.…”