Self‐Assembled Carbon Dot Nanosphere: A Robust, Near‐Infrared Light‐Responsive, and Vein Injectable Photosensitizer

Jia, Qingyan; Ge, Jiechao; Liu, Weimin; Guo, Liang; Zheng, Xiuli; Chen, Shiqing; Chen, Mingxing; Li, Sha; Zhang, Liping; Wang, Mengqi; Zhang, Hongyan; Wang, Pengfei

doi:10.1002/adhm.201601419

Cited by 51 publications

(36 citation statements)

References 118 publications

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“…Making the particles with~100 nm in size and tuning the surface charge will enhance the EPR time in the body. Jia et al [141] prepared the CDs nanosphere with a size of 100 nm through the ionic self-assembly with positive charge CD and negative charge sodium dodecyl benzene sulfonate (SDBS). Further, the CDs spheres were passivated with HOOC-PEG-NH 2 to reduce in vivo cytotoxicity and increase blood circulation time.…”

Section: Fluorescent Cds Conjugated With Phototherapy Agent 521 Flmentioning

confidence: 99%

Recent advance of carbon dots in bio-related applications

Wang

Bao

et al. 2020

J. Phys. Mater.

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Carbon dots (CDs) is a kind of carbon nanoparticles with a plentiful of surface functional groups and tunable emission with different excitation wavelength. Broadly speaking, CDs include carbon nanodots, carbon quantum dots, graphene quantum dots, carbonized polymer dots. Due to the unique nature, they are explored for various applications in the bio-related fields such as bioimaging, sensor for ion and (bio)molecules, catalyst, LED and other fields. They are viewed as great alternative tracers to the current fluorescent biomarkers in personalized nanomedicine and surgery operation monitoring. In this review, we summarized the recent progress in the development of CDs, including improvement in fluorescence properties, two-photon fluorescence, and integration with other modalities as theragnostic agents. Specifically, we discussed the preparation of dual-modal imaging agents to improve the accuracy of diagnosis, the combination of imaging and targeting functionality for the effective accumulation of biomarkers, and the integration of imaging and therapeutic agents to effectively monitor the localization and concentration of therapeutic agents. Finally, the theragnostic agents composed of three functionalities (e.g. targeting, imaging, and therapy) were summarized to provide readers with future perspectives in this field.

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Section: Fluorescent Cds Conjugated With Phototherapy Agent 521 Flmentioning

confidence: 99%

Recent advance of carbon dots in bio-related applications

Wang

Bao

et al. 2020

J. Phys. Mater.

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“…120 To address these limitations, our group prepared an NIR-light-responsive CD nanosphere (CDNS) via self-assembly by using individual CDs as building units. 121 In comparison with individual CDs, the assembled CDNSs exhibit a red-shifted absorption of B50 nm, a broader absorption band from 400 nm to 800 nm, and a stronger NIR emission peak at 730 nm. The positively charged surface of CD changes into the negatively charged surface of CDNSs.…”

Section: Carbon Dots With Intrinsic Photodynamic Propertiesmentioning

confidence: 98%

Recent advances and prospects of carbon dots in cancer nanotheranostics

Jia

Zhao

Liang

et al. 2020

Mater. Chem. Front.

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121

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“…However, in the case of semiorganic nanoparticles such as CDs, there are very few reports on self‐assembly. Also, the reported literature does not demonstrate long‐range ordering and subsequent 2D structure formation attributes . Moreover, the integration of such 2D carbon nanostructures into optoelectronic devices is quite challenging.…”

Section: Carrier Lifetime Studiesmentioning

confidence: 99%

Biowaste‐Derived, Self‐Organized Arrays of High‐Performance 2D Carbon Emitters for Organic Light‐Emitting Diodes

et al. 2020

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Low‐cost flexible organic light‐emitting diodes (OLEDs) with nanoemitter material from waste open up new opportunities for sustainable technology. The common emitter materials generated from waste are carbon dots (CDs). However, these have poor luminescent properties. Further solid‐state emission quenching makes application in display devices challenging. Here, flexible and rigid OLED devices are demonstrated using self‐assembled 2D arrays of CDs derived from waste material, viz., human hair. High‐performance CDs with a quantum yield (QY) of 87%, self‐assembled into 2D arrays, are achieved by improving the crystallinity and decreasing the CDs' size distribution. The CD island array exhibits ultrahigh hole mobility (≈10−1 cm2 V−1 s−1) and significant reduction in solid‐state emission quenching compared to pristine CDs; hence, it is used here as an emitting layer in both indium tin oxide (ITO)‐coated glass and ITO‐coated flexible poly(ethylene terephthalate) (PET) substrate OLED devices, without any hole‐injection layer. The flexible OLED device exhibits a stable, voltage‐independent blue/cyan emission with a record maximum luminescence of 350 cd m−2, whereas the OLED device based on the rigid glass substrate shows a maximum luminescence of 700 cd m−2. This work sets up a platform to develop next‐generation OLED displays using CD emitters derived from the biowaste material.

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Self‐Assembled Carbon Dot Nanosphere: A Robust, Near‐Infrared Light‐Responsive, and Vein Injectable Photosensitizer

Cited by 51 publications

References 118 publications

Recent advance of carbon dots in bio-related applications

Recent advance of carbon dots in bio-related applications

Recent advances and prospects of carbon dots in cancer nanotheranostics

Biowaste‐Derived, Self‐Organized Arrays of High‐Performance 2D Carbon Emitters for Organic Light‐Emitting Diodes

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