Self-aligned TiO2 - Photo reduced graphene oxide hybrid surface for smart bandage application

Electroanalytical Sensor for Diabetic Foot Ulcer Monitoring with Integrated Electronics for Connected Health Application

“…A sharp anodic and depressed cathodic peak at 0.1 V and~À 1.3 V respectively can be observed as shown in Figure 4 (A). This can be attributed to the fact that tyrosinase oxidises hydroquinone to o-quinone and subsequently releasing more electrons, as has been reported by our previous study [2]. The sensor was therefore calibrated at anodic potential of 0.1 V and the direct proportionality of peak anodic current (I pa ) with tyrosine concentration was established (Figure 4 (B)).…”

“…The increase in anodic current with tyrosine concentration can be attributed to enhanced redox cycling, at the electrode-electrolyte interface. The electrocatalysis of tyrosine by tyrosinase is shown in Figure 2 [2] and is further elucidated in SI. In order to justify the major impact of tyrosinase towards tyrosine catalysis, a comparison of voltammograms detailing the response of 500 μM tyrosine at various stages of sensor fabrication is shown in Figure S3 (SI).…”

“…An aqueous solution of 100 μM L-tyrosine was prepared in a 10 mL mixture of 0.1 M PBS (phosphate buffer saline), pH 6.4 [2], and 5 mM [Fe(CN) 6 ] 3À /4À electrolyte. L-tyrosine solutions with concentrations ranging from 5 nM-500 μM were prepared by serial dilutions.…”

“…Diabetic foot ulcer (DFU) can be defined as the inflammation and infection of deep tissues which are associated with neurological abnormalities (neuropathy) and numerous types of vascular disease (angiopathy) at the lower limb of humans [1]. The treatment of DFUs has become a challenge for healthcare providers; due to increasing prevalence of diabetes along with its percentage standing at 7 % in India alone [2]. As reported, 25 % of these patients are expected to suffer from DFU during their lifetime with 12 % of them undergoing major amputations [3,4].…”

In Vitro Electrochemical Behavior of Sol‐Gel Derived Hydroxyapatite/Graphene Oxide Composite Coatings on 316L SS for Biomedical Applications

“…Graphene oxide was extensively used in several fields by many researchers owing to their widespread properties such as extraordinary thermal consistency, electrical conductivity and transportation, anti-corrosive properties, energy storage in battery and super capacitor products, electrochemical sensor applications in human trails (biosensors) and quality control applications, photocatalytic properties which used in the conversion of CO 2 to commercially usable products such as ethanol, acetic acid and methane etc, bio-imaging for the detection of tumors, further used as nano drug carriers for targeted drug delivery systems and also possesses their well proved high mechanical strength with flexibility. [15][16][17][18][19][20][21][22][23][24] Accordingly, the hardness and fracture durability of the HAP can be enhanced by making composite with graphene oxide, which improves the properties of HAP suitable for higher load posture prosthesis. In contrast, graphene oxide consists of different functional groups such as epoxy groups, hydroxyl (À OH) and keto groups on their sidewalls, which keeps it highly hydrophilic.…”