Selenomethionine: an Effective Selenium Source for Sow to Improve Se Distribution, Antioxidant Status, and Growth Performance of Pig Offspring

Abstract

The present study was to investigate the efficiency of maternal selenomethionine intake on growth performance, Se distribution, and antioxidant status of pig offspring by comparing with sodium selenite. A total of 12 sows (Landrace × Yorkshire) with same pregnancy were randomly divided into two groups; each group was replicated six times. These two groups received the same basal gestation and lactation diets containing 0.04 mg Se/kg, supplemented with 0.3 mg Se/kg sodium selenite and selenomethionine (i.e., seneno-DL: -methylseleno), respectively. The feeding trial lasted for 60 days, with 32 and 28 days for gestation and lactation period, respectively. Compared with sodium selenite, maternal selenomethionine intake significantly (p < 0.05) increased the daily weight gain of piglet from birth to weaning. The Se concentration in the colostrum and milk and tissue Se content of piglets were significantly higher (p < 0.05) in the selenomethionine-treated group. The antioxidant status was greatly improved in piglets of selenomethionine-treated group and was illuminated by the increased total antioxidant capability, glutathione peroxidase, superoxide dismutase, and glutathione, and decreased the malondialdehyde level in the organs of piglets. The increased (p < 0.05) triiodothyronine (T(3)) and decreased (p < 0.05) thyroxine (T(4)) concentration indicated the improved protein synthesis and energy production in the selenomethionine-treated group. The increased (p < 0.05) pancreatic digestive enzymes of protease, amylase, and lipase activities indicated that maternal selenomethionine intake may have a positive effect on the degradation and absorption of nutrients in its piglets. In summary, we concluded that maternal selenomethionine intake increased Se deposition, antioxidant status, and nutrient use efficiency, thus providing an effective way to improve the growth performance of piglets from birth to weaning.

Effects of dietary organic selenium on immune responses, total selenium accumulation and digestive system health of marron,Cherax cainii(Austin, 2002)

“…Selenomethionine incorporates into proteins in place of methionine and can be stored (Suzuki & Ogra ) as a reserve in muscle tissues and/or the hepatopancreata of animals and can be extensively utilised and re‐utilised to maintain appropriate Se levels in the body (Aguilar, Charrondiere, Dusemund, Galtier, Gilbert, Gott, Grilli, Guertler, Kass, Koenig, Lambré, Larsen, Leblanc, Mortensen, Parent‐Massin, Pratt, Rietjens, Stankovic, Tobback, Verguieva & Woutersen ). Selenomethionine in the body of animals can trigger and promote the activation of antioxidant enzymes, such as glutathione peroxidase, superoxide dismutase and catalase (Zhan, Qie, Wang, Li & Zhao ; Han, Xie, Liu, Xiao, Liu, Zhu & Yang ), all of which play an important role in enhancing animal immune function (Chiu et al . ; Smitha & Rao ; Han et al .…”

Accumulation and metabolism of selenium by yeast cells

“…Selenium in an organic form exhibits improved properties in terms of biosorption by yeast cells and is less toxic than its inorganic form (Zhan et al 2011). It should be stressed that binding of selenium by yeasts decreases with high contents of sulfur and heavy metals in the culture media.…”

Effects of soybean isoflavone on intestinal antioxidant capacity and cytokines in young piglets fed oxidized fish oil

“…Oxidative stress is lessened by the antioxidants (Otani et al, 2000;Kelley, 2001). Accumulating evidence suggests that supplementation of additives with antioxidant function (such as vitamin E, selenium, glutamine, and arginine) to the feed of piglets (Ban et al, 2004;Huang et al, 2011;Xi et al, 2011;Zhan et al, 2011) can reduce the oxidative stress and protect the intestinal function. Soybean isoflavones (ISFs) are stronger antioxidants, and have been studied extensively (Yousef et al, 2004;Foti et al, 2005;Lee et al, 2005;Jiang et al, 2007;Dixit et al, 2012).…”