Selenium substituted axitinib reduces axitinib side effects and maintains its anti-renal tumor activity

Abstract

Se-axitinib is a selenium substitution of sulfur in axitinib, which reduced the side effect of VEGFR inhibitors and maintained the potent anticancer activity of the original drug.

Polyoxometalate-based ionic liquids: efficient reversible phase transformation-type catalysts for thiolation of alcohols to construct C–S bonds

“…1). [4][5][6][7] In the field of materials, the thioether group also contributes to improving the physical, electronic, and surface properties of functional materials. [8][9][10] The wide range of potential applications of thioethers has stimulated the research enthusiasm of chemists.…”