Selenium species in selenium fortified dietary supplements

Niedzielski, Przemysław; Rudnicka, M.; Wachelka, Marcin; Kozak, Lídia; Rzany, Magda; Woźniak, Magdalena; Kaskow, Zaneta

doi:10.1016/j.foodchem.2015.05.125

Cited by 49 publications

(26 citation statements)

References 17 publications

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“…Supplement #11 contained 70% of the declared level. This trend is similar to a recent literature report in which Bakirdere et al (2015) examined six Turkish pharmaceutical tablets and found one to be outside the ±30% of declared range, while Niedzielski et al (2016) analyzed 86 supplements on the Polish market and found nonconformity in 48 samples (also ±30%). For quality assurance, SELM-1 was analyzed and the determined wet weight concentration of Se was 1820 mg Se kg −1 (1% RSD), which, when adjusted for a ~4% moisture content and compared to the revised certified value of total selenium of 2031 mg kg −1 , yielded a 93% accuracy.…”

Section: Resultssupporting

confidence: 90%

“…Recent publications have noted that many selenium supplements available to the public either do not contain the labeled amount of selenium or lack the labeled form (Bakirdere, Volkan, & Ataman, 2015; Gosetti et al, 2007; Niedzielski et al, 2016). Total selenium content can routinely be determined using inductively coupled plasma mass spectrometric (ICP-MS) analysis.…”

Section: Introductionmentioning

confidence: 99%

“…The most commonly used separation methods are reversed phase ion pairing (RP-IP), anion exchange, and cation exchange. The work by Niedzielski et al (2016) examined 86 selenium fortified supplements for iSe versus the organic forms, but they did not distinguish among organic species. The report by Bakirdere et al (2015) separated Se(IV), Se(VI), SeMet and SeCys 2 , while Hsieh and Jiang (2013) included MeSeCys; neither report accounted for the oxidized form of SeMet (SeOMet) or other related degradation products.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of selenium in dietary supplements using elemental speciation

Kubachka¹,

Hanley²,

Mantha³

et al. 2017

Food Chemistry

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Selenium-enriched dietary supplements containing various selenium compounds are readily available to consumers. To ensure proper selenium intake and consumer confidence, these dietary supplements must be safe and have accurate label claims. Varying properties among selenium species requires information beyond total selenium concentration to fully evaluate health risk/benefits A LC-ICP-MS method was developed and multiple extraction methods were implemented for targeted analysis of common “seleno-amino acids” and related oxidation products, selenate, selenite, and other species relatable to the quality and/or accuracy of the labeled selenium ingredients. Ultimately, a heated water extraction was applied to recover selenium species from non-selenized yeast supplements in capsule, tablet, and liquid forms. For selenized yeast supplements, inorganic selenium was monitored as a means of assessing selenium yeast quality. A variety of commercially available selenium supplements were evaluated and discrepancies between labeled ingredients and detected species were noted.

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Section: Resultssupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluation of selenium in dietary supplements using elemental speciation

Kubachka¹,

Hanley²,

Mantha³

et al. 2017

Food Chemistry

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“…Over the past few years, Se species content, especially its low concentrations in food, has been explored using a number of methods (Niedzielski et al, 2016). However, extracting the mineral completely from the food matrix without affecting its original speciation is difficult, which makes the analysis method usable for routine applications.…”

Section: Optimisation Of Extraction Methods Of Se Speciesmentioning

confidence: 99%

Se in Se‐enriched peanut, and losses during peanut protein preparation

Lin

Luo

et al. 2017

Int J of Food Sci Tech

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Summary This study determined the Se species in Se‐enriched peanut, and Se losses during peanut protein processing by enzymatic extraction, high‐performance liquid chromatography (HPLC) separation and inductively coupled plasma‐mass spectrometry determination. The study revealed that mixed enzymes (protease and lipase, 2:1 w/w) in Na2S2O3, assisted by 1 h ultrasonic processing, could effectively extract Se speciation from defatted peanut powder. Separation of organic Se by HPLC was optimised using pentafluoropropionic anhydride at a concentration of 0.1% in 2% methanol as mobile phase. Selenomethionine is the dominant Se species in peanut, accounting for 65% of the total Se. During the peanut protein preparation, nearly 37% of Se losses were due to the complexity of the multistage process. The loss can be ascribed to volatilisation, dissolution, degradation or other physical modes of transfer or loss.

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“…al. 47 realizaram a separação de todas as formas de Se presente em amostras de suplementos alimentares empregando HPLC. As amostras inicialmente foram submetidas ao processo de digestão ácida e, posterior à separação por HPLC, ocorreu a atomização em GF e a detecção de Se por AAS.…”

Section: Métodos Cromatográficosunclassified

Compostos Orgânicos E Inorgânicos Contendo Selênio: Revisão De Métodos Analíticos E Perspectivas Para Análises Químicas

et al. 2017

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publicado na web em 13/11/2017 ORGANIC AND INORGANIC COMPOUNDS CONTAINING SELENIUM: ANALYTICAL METHODS REVIEW AND CHEMICAL ANALYSIS PERSPECTIVES. This article critically reviews the spectrometric, chromatographic and electroanalytical methods applied for the identification and quantification of organic and inorganic compounds containing Se and their applications in food, biological and natural water samples. The main characteristics, advantages and disadvantages of each analytical method are presented, and special attention is paid to sample preparation strategies prior to identification and quantification. Perspectives of research on new analytical procedures with improved speed, sensitivity, selectivity, accuracy, and mainly environmentally friendly, are also reported.Keywords: selenium; analytical determination; spectrometry; chromatography; electroanalysis; speciation. CONSIDERAÇÕES GERAISA magnífica máquina humana necessita de diversos nutrientes, os quais são o combustível para a manutenção do seu perfeito funcionamento. Dependendo das quantidades necessárias, estes nutrientes são classificados como macronutrientes (carboidratos, proteínas, lipídios e fibras) e micronutrientes (vitaminas e minerais). Estes compostos apresentam funções específicas e, consequentemente, diferentes concentrações ideais para o desempenho de suas funções metabólicas. A ingestão diária de nutrientes dependerá da composição química da dieta alimentar. 1Dentre os principais micronutrientes destacam-se ferro, zinco, cobre, selênio, cromo, iodo, molibdênio, manganês, silício, níquel, boro, vanádio, flúor, arsênio, alumínio, lítio e estanho, seja em suas formas orgânicas ou inorgânicas. Estes compostos desempenham suas respectivas atividades metabólicas quando presentes em concentrações abaixo de microgramas por grama (µg g -1 ). Entretanto, acima destas concentrações podem apresentar toxicidade ao organismo humano. 1 Selênio, apresentado com a sigla Se, é um micronutriente essencial para a dieta humana, em função das suas propriedades antioxidantes, auxiliando no retardamento do envelhecimento, no tratamento de doenças cardiovasculares e neoplasias, distrofia muscular, esclerose múltipla, osteoporose, reprodutividade, e desordem muscular.2,3 Alguns estudos indicam sua importância no metabolismo e funcionamento da tireóide e sua atuação no metabolismo dos ácidos graxos, juntamente com a vitamina E (α-tocoferol). 4,5 Assim, o Conselho Americano de Alimentação e Nutrição (Food and Nutrition Board, EUA), 6 recomenda a ingestão diária de 15 a 20 µg por dia, de 55 µg por dia e 70 µg por dia, para crianças, mulheres lactantes e outros adultos, respectivamente. Entretanto, o limite má-ximo de ingestão diário para uma pessoa adulta não deve ultrapassar 400 µg.A diferença entre a concentração essencial de Se, a deficiência ou a toxicidade é muito pequena. As concentrações ingeridas são fortemente dependentes do nível de concentração em alimentos e na quantidade de alimento ingerido.7 O consumo diário abaixo de 0,1 µg de Se por grama de aliment...

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Selenium species in selenium fortified dietary supplements

Cited by 49 publications

References 17 publications

Evaluation of selenium in dietary supplements using elemental speciation

Evaluation of selenium in dietary supplements using elemental speciation

Se in Se‐enriched peanut, and losses during peanut protein preparation

Compostos Orgânicos E Inorgânicos Contendo Selênio: Revisão De Métodos Analíticos E Perspectivas Para Análises Químicas

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