Selenium, cadmium and diazinon insecticide in tissues of rats after peroral exposure

Toman, R.; Tunegová, Martina

doi:10.5219/827

Cited by 3 publications

(2 citation statements)

References 54 publications

(10 reference statements)

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“…Testosterone concentration can decrease in men after acute exposure to pesticides, such as carbamates, thio- and dithiocarbamates, pyrethroids, chlorophenoxy acids, chloromethylphosphoric acids, and organophosphatases [ 86 ]. Pesticides like diazinon can decrease spermatozoa motility and morphology [ 87 ]. Bendiocarb administration can disrupt spermatogenesis by impairing the ultrastructure of rabbit spermatozoa.…”

Section: Environmental Factorsmentioning

confidence: 99%

Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction

et al. 2021

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Hypogonadism is an endocrine disorder characterized by inadequate serum testosterone production by the Leydig cells of the testis. It is triggered by alterations in the hypothalamic–pituitary–gonadal axis. Erectile dysfunction (ED) is another common disorder in men that involves an alteration in erectile response–organic, relational, or psychological. The incidence of hypogonadism and ED is common in men aged over 40 years. Hypogonadism (including late-onset hypogonadism) and ED may be linked to several environmental factors-induced oxidative stresses. The factors mainly include exposure to pesticides, radiation, air pollution, heavy metals and other endocrine-disrupting chemicals. These environmental risk factors may induce oxidative stress and lead to hormonal dysfunctions. To better understand the subject, the study used many keywords, including “hypogonadism”, “late-onset hypogonadism”, “testosterone”, “erectile dysfunction”, “reactive oxygen species”, “oxidative stress”, and “environmental pollution” in major online databases, such as SCOPUS and PUBMED to extract relevant scientific information. Based on these parameters, this review summarizes a comprehensive insight into the important environmental issues that may have a direct or indirect association with hypogonadism and ED in men. The study concludes that environmental factors-induced oxidative stress may cause infertility in men. The hypothesis and outcomes were reviewed critically, and the mechanistic approaches are applied through oxidant-sensitive pathways. This study also provides reccomendations on future therapeutic interventions and protective measures against such adverse environmental factors-induced hypogonadism and ED.

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Section: Environmental Factorsmentioning

confidence: 99%

Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction

et al. 2021

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“…Dairy animals ingest metals while grazing on the pasture and when fed on contaminated concentrate feeds. Toxic metals such as lead and cadmium are common air pollutants and are emitted into the air as a result of various industrial activities [9,10]. Various industrial environmental contamination of soil, waters, foods, and plants with these metals causes their incorporation into the food chain and imposes a great threat to human and animal health [11].…”

Section: Introductionmentioning

confidence: 99%

Changes in the concentrations of selected toxic and essential elements in ewe milk from area with a potentially undisturbed environment

et al. 2021

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The aim of this study was to evaluate the effect of lactation on the concentration of selected essential and toxic elements in sheep milk from an area of Slovakia with a potentially undisturbed environment and to find out the actual contamination of the selected area, in the aspect of its environmental character. The research was conducted with 400 sheep (Tsigai breed), and the milk samples were taken during the lactation periods (early, middle and late lactation stage). Sheep were reared on the extensive pastures, reared indoors afterward, fed with pasture ad libitum. Milk samples were collected after morning and afternoon milking. The samples of milk were analysed toxic and essential elements (Ca, Se, Mg, Zn, Fe, Cu, As, Cd, Hg, Ni, Pb) by the method of atomic absorption spectroscopy (AAS). The macro elements concentration in milk changes following the stages of lactation (p<0.05). There was found that Ca milk concentration increased gradually in the following stages of lactation while Mg, Se, and Fe only in the last stage of lactation. The Zn concentration in milk was the highest during summer (p<0.05). Simultaneously the contents of essential elements (Cu) and toxic elements (As, Cd, Hg, Ni, Pb) in milk were very low, below the limit of quantification. In conclusion, ewe's milk from potentially analysed areas of Slovakia is safe and poses no risk to consumer health, and is suitable for use directly or in dairy processing.

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Occurrence of selected metals in feed and sheep´s milk from areas with different environmental burden

Tunegová

Toman

Tančin

et al. 2018

Potr. S. J. F. Sci.

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The content of selected essential elements and toxic metals in feed and sheep's milk from areas with different parts of Slovak Republic was analyzed. Region of Novoť (undisturbed environment; North Slovakia) and region of Klátova Nová Ves (widely disturbed environment; Western Slovakia) were under investigation. Eleven metals have been analyzed (essential elements -calcium, zinc, selenium, iron, magnesium, copper; toxic elementsarsenic, mercury, lead, cadmium, nickel). Samples of feeds and milk were collected five-times during the year (spring and autumn season). Analyses of samples were performed by certified testing laboratory Eurofins Bel/Novamann (Nové Zámky, Slovak Republic). Analyses were performed by routine methods, according to the valid methodologies. The results showed significantly higher content of selected essential elements in feed in spring season from area with widely disturbed environment (Klátova Nová Ves). Significantly higher content of essential elements in milk was on farm of Novoť (undisturbed environment). Occurrence of toxic metals in feed from area with widely disturbed environment in spring season did not affect their content in milk. It can be concluded, that the use of milk of sheep from these areas for direct use or for dairy products processing is appropriate, safe and poses no health risk for the consumers.

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Selenium, cadmium and diazinon insecticide in tissues of rats after peroral exposure

Cited by 3 publications

References 54 publications

Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction

Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction

Changes in the concentrations of selected toxic and essential elements in ewe milk from area with a potentially undisturbed environment

Occurrence of selected metals in feed and sheep´s milk from areas with different environmental burden

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