Selective voltammetric determination of α-lipoic acid on the electrode modified with SnO2 nanoparticles and cetyltriphenylphosphonium bromide

Voltammetric Determination of Hesperidin on the Electrode Modified with SnO2 Nanoparticles and Surfactants

“…Electrochemically inert metal oxide nanoparticles in particular SnO 2 NPs can be considered as an alternative for the electrode surface modification. Chemical inertness, high surface area and biocompartibility can be successfully applied in creation of novel modified electrodes [29][30][31]. Nevertheless, there are two problems of their application in electroanalysis caused by insufficient conductivity and aggregation in dispersions.…”

Easily Prepared Co3O4Doped Porous Carbon Material Decorated with Single‐wall Carbon Nanotubes Applied in Voltammetric Sensing of Antioxidant α‐lipoic Acid

“…LOD of the proposed method was better and once comparable in the most of reported articles where researchers have used electrodes from GC (5.75 μM and 1.8 μM), Pt (13.15 μM), fluorine‐doped tin oxide electrodes (3.68 μM), GCE modified with MWCNT (19 μM) and SnO 2 nanoparticles (0.13 μM)[15, 16, 17, 19, 21, 22], while the better LOD with a much smaller working range was reported at mercury electrode using adsorptive stripping anodic voltammetric technique (linear range of 0.050–0.90 μM and LOD of 0.012 μM [14]. It could be seen that only DPV and amperometric determinations at BDDE [18], more complicate pyrolytic graphite electrode modified with cobalt phthalocyanine [20] and more sensitive square‐wave anodic stripping voltammetry at screen‐printed graphene electrodes modified with manganese (IV) oxide [22] exceed validation method parameters obtained in this study. It is obvious that our electrode is comparable with the reported ones.…”

“…The use of different electrode materials or modifiers can also cause different reaction mechanisms on the electrode surface. Although the reduction of α‐lipoic acid was recorded at a dropping mercury electrode and rotating disc electrode of mercury on gold [34], the irreversible oxidation of α‐lipoic acid at high anodic potentials was confirmed at the most of used electrodes (platinium and carbon based and a lot of modified electrodes [15–23]). Based on Tafel plot of CV recorded at scan rate of 25 mV/s (Figure 4b), with corresponding regression line E (V)=0.097 log I (A)+1.449 and Tafel slope of 97 mV (i. e.between 60 and 120 mV/dec), it was assumed that the electro‐oxidation occurs via an electrochemical–chemical (EC) mechanism, with the chemical determining step [35], similarly to previously reported results [17, 19].…”

“…The electrochemical approach to LA quantification has significant advantages over other methods, not only in terms of simplicity, speed, and no‐expensive apparatus but primarily due to the elimination of limitations in real sample applications originating from the matrix. α‐Lipoic acid was determined at unmodified electrodes, mercury electrode [14], platinum electrode [15], glassy carbon [16, 17] boron‐doped diamond electrode [18], while for modification of LA sensitive electrodes were used: fluorine‐doped tin oxide [19], cobalt phthalocyanine at pyrolytic graphite [20], multi‐walled carbon nanotubes [21], SnO 2 nanoparticles and cetyltriphenylphosphonium bromide [22] and also manganese (IV) oxide on screen‐printed graphene electrodes [23].…”

Recent advances in applications of surfactant‐based voltammetric sensors

“…The best characteristics are observed for a GCE modified by dispersion of SnO 2 in cationic CPB (SnO 2 –CPB/GCE) (Ziyatdinova, Antonova, et al, 2018). Moreover, a sensitive voltammetric approach was applied to quantify α‐lipoic acid using the modified GCE with SnO 2 nanoparticles (SnO 2 NPs), which had been dispersed in cetyltriphenylphosphonium bromide (CTPPB) (SnO 2 NP‐CTPPB/GCE), and the resultant approach was selected for the pharmaceutical dosage form analysis (Ziyatdinova, Antonova, et al, 2019).…”