Selective Sebaceous Gland Electrothermolysis Using a Single Microneedle Radiofrequency Device for Acne Patients: A Prospective Randomized Controlled Study

Ahn, Ga Ram; Kim, Jae Min; Park, Su Jung; Li, Kapsok; Kim, Beom Joon

doi:10.1002/lsm.23152

Cited by 17 publications

(16 citation statements)

References 20 publications

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“…In studies that used RF for acne or scarring, lesion count and sebum were measured for objective improvement. 28,[35][36][37] Three-dimensional imaging objectified skin topography of acne scars, fat content, and aging. 18,32,[38][39][40][41][42] Ultrasound measured fat thickness and skin density.…”

Section: Resultsmentioning

confidence: 99%

“…Supporting Information Data outlines the efficacy measurement tools used. In studies that used RF for acne or scarring, lesion count and sebum were measured for objective improvement 28,35–37 . Three‐dimensional imaging objectified skin topography of acne scars, fat content, and aging 18,32,38–42 .…”

Section: Resultsmentioning

confidence: 99%

“…A prospective, randomized controlled study over a 12-week period demonstrated that intralesional monopolar RF significantly reduces facial acne lesion count (p = 0.03) compared to control (microneedling and extraction). 35 Similarly, a prospective, randomized study showed that fractional microneedling with RF improved seborrhea and acne and showed superior subjective assessments for acne, skin texture, and acne scars than diode laser. 28 An undesirable complication of acne is atrophic (dermal depression) or hypertrophic/keloidal scars.…”

Section: Retrospective Studymentioning

confidence: 98%

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Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review

Austin

Struble²,

Quatela

2021

Lasers Surg Med

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Background: Radiofrequency technology has emerged as a treatment for aesthetic rejuvenation.Objective: To examine radiofrequency for facial and neck rejuvenation, clinical studies were assessed on effectiveness and safety of radiofrequency for acne, acne scars, and facial aging by subjective and objective measures. Methods: A systematic literature review was performed. Eligibility criteria included articles in English, primary literature, clinical or ex vivo studies, use of radiofrequency, and face or neck treatment. Ablative techniques, home-use devices, combined modalities, and studies unrelated to rejuvenation were excluded. All studies were appraised for quality and biases. Results: We identified 121 articles. Radiofrequency effectively treated acne by reducing sebum levels and lesion count and improving acne scars. Radiofrequency demonstrated a volumetric reduction in facial fat, and improved skin laxity, elasticity, and global skin aesthetic. Patient satisfaction was higher for those desiring modest rejuvenation. There were histological changes consistent with repair response, neocollagenesis, and neoelastinogenesis. Radiofrequency was safe apart from one patient who developed a neck fistula. Conclusion: Most studies demonstrated radiofrequency treatment of acne, scars, or facial rhytids had positive subjective improvement ratings. Objective studies demonstrated reduction of acne, decreased scarring, lifting effect, improvement in elasticity and collagen, volumetric fat changes, and wrinkle reduction.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Retrospective Studymentioning

confidence: 98%

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Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review

Austin

Struble²,

Quatela

2021

Lasers Surg Med

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“…This has led to the development of technologies with a more favorable profile, such as FRF. FRF devices have been proven to decrease the propensity for postinflammatory hyperpigmentation and the aforementioned problems of ablative lasers, all while achieving a similar level of acne scar reduction 13,27,28 . The efficacy of FRF compared to other treatment modalities for acne scarring has previously been investigated in a Cochrane review 29 .…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of fractional radiofrequency for the treatment and reduction of acne scarring: A prospective study

Eubanks

Solomon

2021

Lasers Surg Med

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Objectives: Skin rejuvenation with radiofrequency has been a widely used treatment modality for the safe and efficient remodeling of the dermis and revision of textural irregularities, achieved with minimal downtime. The efficacy of fractional radiofrequency (FRF) specifically for acne scarring has not been widely established. The objective of this clinical trial was to establish the efficacy and safety of FRF for moderate to severe acne scarring in a wide range of Fitzpatrick skin types using two different applicator tips to deliver energy to the skin (80-pin of up to 124 mJ/pin and 160-pin of up to 62 mJ/pin). Methods: Enrolled subjects received a series of three FRF treatments to the full face, each 4 weeks apart. A visual analog scale was utilized to assess pain of the treatment. Subject satisfaction questionnaires were completed at follow-up visits at 6 and 12 weeks post final treatment. Photographs were graded for change by three blinded evaluators using the Global Aesthetic Improvement Scale (GAIS). Results: Image sets of 23 enrolled subjects were assessed by blinded evaluation, showing a statistically significant improvement (p = 0.009) from the baseline visit to the 12-week follow-up on the GAIS for acne scarring. Subject satisfaction was high with subjects giving an average satisfaction score of 3.27 ("satisfied") out of 4. Pain was "mild" as treatments were rated an average of 2.15 on a 10-point visual analog scale. The GAIS score of the 80-pin tip improved patients' acne scars treated with that applicator by 1.06 points and 0.85 for the 160-pin tip. Ninety-five percent (95.5%) of subjects reported either a mild, moderate, or significant improvement to their treatment area. Ninety-one percent of subjects reported that they would recommend the treatment to a friend. Conclusion: FRF produced a statistically significant improvement in acne scarring when assessed by independent blinded evaluators. No serious adverse events resulted from treatment by either applicator tip. Treatment pain was low and tolerable among subjects of all Fitzpatrick skin types. Subjects had high levels of satisfaction with the results.

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“…Various RF devices have been developed and used to treat wrinkles, acne, hyperhidrosis, etc. A recent study on treatment with RF devices for acne vulgaris, a disease in which an overactive sebaceous gland may be part of its pathogenesis, has confirmed that a micro-needling RF device can improve sebum production by decreasing the sebaceous gland [3].…”

Section: Introductionmentioning

confidence: 97%

Can a radiofrequency device reduce the pore size?

Suh¹,

Jeong

Lee³

et al. 2021

Lasers Med Sci

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A facial pore is an empty funnel-shaped structure filled with cornified cylindrical plugs that can be cosmetically bothersome to some patients. In the previous report, the new unipolar radiofrequency (RF) device with a vacuum showed excellent skin tightening and patient satisfaction with improved pores. This study aims to confirm the treatment's efficacy with the new unipolar RF device on facial dilated pores by measuring quantitative sebum production differences and doing a histologic examination of pore size. Twelve patients who visited the dermatologic clinic without other underlying inflammatory facial skin diseases were included, regardless of the patient's age or sex. All patients received five successive treatments at 2-week intervals. We assessed all changes in sebum production levels, melanin index, erythema index before and after treatment, along with overall improvement (reduction of pore size, skin tone, skin texture, and skin laxity). In the five patients who agreed in advance, a biopsy of the pore lesion was taken before and 1 month after the last treatment with hematoxylin and eosin (H&E) staining, Masson's trichrome (M-T) staining, and Victoria blue staining. We observed a significant reduction of sebum production and melanin index after using the new unipolar RF device with a vacuum (sebum production, p = 0.011; MI, p = 0.004). In evaluating patient satisfaction for four categories, the patients showed a moderate to the excellent improvement of more than 50% in their condition except for skin tones. The average pore size decreased by 41.7% in the histological examination, from 64.98 to 37.86 μm. Additionally, we observed an overall decreased sebaceous gland in the dermis and the proliferation of dermal collagen fiber. The number of elastic bundles in the D-E junction was increased after treatment. The nonablative unipolar RF devices with a vacuum can improve dilated pores with a dual mechanism (collagen regeneration and reduction of sebum production), with much less pain than other RF devices.

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Selective Sebaceous Gland Electrothermolysis Using a Single Microneedle Radiofrequency Device for Acne Patients: A Prospective Randomized Controlled Study

Cited by 17 publications

References 20 publications

Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review

Evaluating the effectiveness and safety of radiofrequency for face and neck rejuvenation: A systematic review

Safety and efficacy of fractional radiofrequency for the treatment and reduction of acne scarring: A prospective study

Can a radiofrequency device reduce the pore size?

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