Selection for feed efficiency elicits different postprandial plasma metabolite profiles in response to poor hygiene of housing conditions in growing pigs

Fraga, Alícia Zem; Louveau, Isabelle; Campos, Paulo Henrique Reis Furtado; Hauschild, Luciano; Floc'H, Nathalie Le

doi:10.1371/journal.pone.0246216

Cited by 6 publications

(6 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…During the post-weaning period, pigs fed AAP diet had lower plasma haptoglobin concentrations, a trend to lower values of dROM and ISO, and greater concentrations of vitamins E and A compared to CNT pigs. Haptoglobin is a major acute phase protein in pigs and an increase in its plasma concentration is an indicator of inflammation and/or infection [ 13 ]. Weaning is known to increase the concentration of haptoglobin in the plasma [ 2 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

“…All pigs were fed the same standard diet formulated to meet the nutritional requirements of growing pigs (9.47 MJ of net energy/kg, starch 44.2%; fat 3.1%; crude protein 15.3% and 8.3 g of standardized ileal digestible lysine (SID Lys), SID Lys/kg). The model of good and poor hygiene condition study was described in detail in previous studies [ 13 , 28 ]. To summarize, poor housing conditions consisted of no cleaning nor sanitation of the room after a previous occupation by non-experimental pigs, whereas for good hygiene conditions, the room was cleaned daily, in addition to the application of optimal aeration rate and temperature and strict biosecurity precautions.…”

Section: Methodsmentioning

confidence: 99%

“…Automated enzymatic methods using a multianalyzer apparatus (Konelab20i, Thermo Electron Corporation, Cergy, France) were used to determine plasma concentrations of dROM and biological antioxidant potential (BAP) (dROM and BAP tests, references MC003 and MC437, respectively; Diacron, Grosseto, Italy). Oxidative stress index was calculated as the dROM to BAP ratio as previously described [ 13 ]. Plasma concentrations of vitamins E and A were assayed by liquid chromatography (HPLC, Waters Alliance) on a dedicated column (Chromsystems, Germany).…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

A blend of functional amino acids and grape polyphenols improves the pig capacity to cope with an inflammatory challenge caused by poor hygiene of housing conditions

et al. 2023

Self Cite

View full text Add to dashboard Cite

Background Dietary supplementation with a blend of functional amino acids (AA) and grape extract polyphenols contributes to preserve intestinal health and growth performance of piglets during the post-weaning period. In the present experiment, we assessed if a supplementation with a mix of AA and grape extract polyphenols during the post-weaning period would persist to improve the pig capacity to cope with a subsequent challenge caused by poor hygiene of housing conditions. Eighty pigs weaned at 28 days of age were fed a standard diet supplemented (AAP) or not (CNT) with 0.2% of a blend of AA (glutamine, arginine, cystine, valine, isoleucine, and leucine) and grape extract polyphenols during the post-weaning period (from week 0 to 6). At week 6, pigs were transferred to a growing unit where 50% of pigs previously fed AAP and CNT diets were housed in good and the other 50% in poor hygiene conditions for 3 weeks (from week 7 to 9; challenge period). All pigs were fed a standard growing diet that was not supplemented with AAP. We measured pig growth performance, plasma indicators of inflammation, digestive integrity, and oxidative status, and scored fecal consistency. Differences were considered significant at P ≤ 0.05. Results One week post-weaning, pigs fed AAP had lower plasma concentrations of haptoglobin than CNT pigs (P = 0.03). Six weeks post-weaning, plasma concentrations of diamine oxidase (DAO) were lower (P = 0.03) whereas those of vitamin E and A were greater (P ≤ 0.05) in pigs fed AAP compared to CNT pigs. The prevalence of diarrhea was higher in CNT pigs compared to AAP pigs (P < 0.01). During the challenge period, only pigs previously fed CNT diet had lower growth rate in poor than good conditions (P ≤ 0.05). They had also greater plasma concentrations of haptoglobin and oxidative stress index (OSI) and lower plasma concentrations of vitamin E in poor than good hygiene conditions (P ≤ 0.05). Conclusions Pigs fed AAP diet during post-weaning had less diarrhea and plasma concentrations of a digestive integrity marker, as well as greater plasma concentrations of antioxidant indicators during the post-weaning period. The beneficial effects of AAP supplementation persisted after the post-weaning period as evidenced by the absence of effects of the hygiene challenge on growth and health indicators in pigs previously fed APP. This clearly indicated a greater ability of pigs fed AAP to cope with the poor hygiene conditions.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

A blend of functional amino acids and grape polyphenols improves the pig capacity to cope with an inflammatory challenge caused by poor hygiene of housing conditions

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…Generally, the inclusion levels of ingredients are calculated to obtain optimal animal performance, which means an efficient use of the agricultural land to produce animal protein. Based on a previous study, pigs with increased insulin plasma levels have an improved use of amino acids such as lysine, tryptophan, and arginine [ 15 ]. Furthermore, insulin allows the use of amino acids for muscle protein synthesis [ 16 ], suggesting that it will support the growth of pigs.…”

Section: Introductionmentioning

confidence: 99%

Effects of the Inclusion of Dietary Bitter Gourd (Momordica charantia) on the Performance and Carcass Characteristics of Pigs: Potential Application in the Feed Chain

Guan

Santos

Koopmans

et al. 2023

Animals

View full text Add to dashboard Cite

The objective of this study was to determine the effect of bitter gourd (BG) leftovers (stems and leaves) as an alternative dietary ingredient on pig performance, carcass characteristics, serum parameters (urea, insulin, and leptin levels), and faecal consistency. Healthy Tempo × Great Yorkshire and Landrace pigs (N = 240; 120 gilts and 120 boars) weighing 25.8 kg (9–10 weeks of age) were randomly assigned to three treatments (eight pens per treatment; each pen with five gilts and five boars). The three treatments consisted of a non-supplemented commercial diet (control; CON) and a CON diet supplemented with 6.5 g/kg BG (BG1) or 13 g/kg BG (BG2). Pigs were fed the experimental diets until slaughter (120 kg body weight; BW). Feed intake was recorded daily and calculated for each experimental phase (i.e., days 0–36, days 36–66, days 66–98, and the overall experimental period). Average daily feed intake (ADFI), average daily gain (ADG), and feed conversion ratio (FCR) were calculated. The frequencies of visiting the feed station and of feeding were recorded daily. Faecal scores (FS) for consistency were measured per pen twice weekly. On the day of slaughter, two pigs per pen (one male and one female) were randomly selected for the measurement of muscle thickness and blood collection. At the slaughterhouse, carcass weight, dressing percentage, back fat thickness, muscle depth, and lean meat percentage were recorded. Data were analysed using ANOVA, with the pen as the experimental unit. Diets BG1 or BG2 did not affect the performance of the pigs, except for a significant decrease in the ADG of the pigs fed the BG2 diet in the feeding period of 50–80 kg. However, no differences in performance were observed in the overall experimental period. Faecal scores, carcass quality, and serum levels of urea, insulin, and leptin were also not affected by the diet. In summary, leftovers (stems and leaves) of BG can be successfully added to the diet of growing-finishing pigs without interfering with performance and carcass characteristics.

show abstract

“…Feed efficiency in piglets correlates with specific microbiota and with bacterialrelated metabolites in intestine (Wang et al, 2021). Based on metabolic research in the postprandial period in piglets, it has been shown that piglets with lower residual feed intake grow much better in poor hygienic conditions, due to better use of amino acids and better postprandial glucose and insulin dynamics (Zem Fraga et al, 2021). In a study by Kabalin et al (2017) compared metabolic parameters in piglets of low and high birth weight.…”

Section: Introductionmentioning

confidence: 99%

The correlation between body weight, body weight gain and blood parameters in pigs at birth and weaning

Mirkov

Radović

Cincović

et al. 2023

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

The aim of study was to determine the relationship between metabolic parameters, body weight and body growth of piglets at birth and weaning. The experiment included 80 piglets obtained from F1 generation sows. Body weight was measured at birth (BW0), 24h (BW1) after birth and on day 25 (at weaning, BW2). Blood sampling was performed at the beginning of life (3rd day after birth) and at weaning (21st day after birth). BW0 and BW1 positively correlated with cholesterol and negatively with urea values at the beginning of life and RBC values at weaning. BW2 positively correlates with albumin and cortisol values at the beginning of life, total proteins, and globulins at weaning, and negatively correlates with erythrocyte values at weaning. Piglet growth from birth to weaning (BWG2-0) correlates positively with total proteins, albumin, and cortisol at the beginning of life and total proteins at weaning. ROC analysis shows that MCHC, TPROT, GLOB, CHOL and AST at the beginning of life can distinguish fast-growing from slow-growing piglets from birth to weaning period. The use of blood parameters enables early recognition of growth rate in piglets, which can help to optimize all further steps to achieve the best possible growth.

show abstract

Selection for feed efficiency elicits different postprandial plasma metabolite profiles in response to poor hygiene of housing conditions in growing pigs

Cited by 6 publications

References 32 publications

A blend of functional amino acids and grape polyphenols improves the pig capacity to cope with an inflammatory challenge caused by poor hygiene of housing conditions

A blend of functional amino acids and grape polyphenols improves the pig capacity to cope with an inflammatory challenge caused by poor hygiene of housing conditions

Effects of the Inclusion of Dietary Bitter Gourd (Momordica charantia) on the Performance and Carcass Characteristics of Pigs: Potential Application in the Feed Chain

The correlation between body weight, body weight gain and blood parameters in pigs at birth and weaning

Contact Info

Product

Resources

About