Selected commercial plants: A review of extraction and isolation of bioactive compounds and their pharmacological market value

Patra, Jayanta Kumar; Das, Gitishree; Lee, Siyoung; Kang, Seong-Gil; Shin, Han‐Seung

doi:10.1016/j.tifs.2018.10.001

Cited by 102 publications

(59 citation statements)

References 200 publications

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“…Furthermore, the choice of the appropriate analytical method (especially extraction protocol) depends largely on the matrix itself. For example, bioactive compounds are nowadays extracted from a wide variety of plant matrices, including medicinal plants [46], cereals [47,48], fruits and vegetables [49], edible flowers [50], nuts [51], etc. Of particular importance is certainly the extraction of bioactive compounds from the nus-products of various industries, especially the food industry [52][53][54][55][56].…”

Section: Analytical Procedures For Determination Of Bioactive Compounmentioning

confidence: 99%

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Ivanović

Razboršek

Kolar

2020

Plants

120

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The growing interest of the food, pharmaceutical and cosmetics industries in naturally occurring bioactive compounds or secondary plant metabolites also leads to a growing demand for the development of new and more effective analysis and isolation techniques. The extraction of bioactive compounds from plant material has always been a challenge, accompanied by increasingly strict control requirements for the final products and a growing interest in environmental protection. However, great efforts have been made in this direction and today a considerable number of innovative extraction techniques have been developed using green, environmentally friendly solvents. These solvents include the deep eutectic solvents (DES) and their natural equivalents, the natural deep eutectic solvents (NADES). Due to their adjustable physical-chemical properties and their green character, it is expected that DES/NADES could be the most widely used solvents in the future, not only in extraction processes but also in other research areas such as catalysis, electrochemistry or organic synthesis. Consequently, this review provided an up-to-date systematic overview of the use of DES/NADES in combination with innovative extraction techniques for the isolation of bioactive compounds from various plant materials. The topicality of the field was confirmed by a detailed search on the platform WoS (Web of Science), which resulted in more than 100 original research papers on DES/NADES for bioactive compounds in the last three years. Besides the isolation of bioactive compounds from plants, different analytical methods are presented and discussed.

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Section: Analytical Procedures For Determination Of Bioactive Compounmentioning

confidence: 99%

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Ivanović

Razboršek

Kolar

2020

Plants

120

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“…On the other hand, most of the compounds permeated in the three processes (MF, UF, or NF) are phenolic compounds, which have been widely recognized by their antioxidant properties . Recently, Cassano et al and Castro‐Muñoz et al reported compilations in which several studies focus on the recovery of phenolic compounds from natural sources (e.g., apple, orange, pomegranate, pineapple, and grape) and agro‐food byproducts (e.g., wastewater from nixtamalization, mill wastewater, and liquor pressing) using membrane‐based technologies.…”

Section: Potentialities Of the Recovered Metabolitesmentioning

confidence: 99%

“…The food industry is not the only area of application for this type of compounds that are extracted from fermentation broths. In addition, phenolic compounds are also important within the cosmetic and pharmaceutical industry for their antioxidant properties . At this point, it is clear that the compounds extracted from fermentation broths have multiple and promising applications.…”

Section: Potentialities Of the Recovered Metabolitesmentioning

confidence: 99%

Metabolites recovery from fermentation broths via pressure‐driven membrane processes

Díaz‐Montes

Castro‐Muñoz

2019

Asia-Pacific J Chem Eng

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The production of specific metabolites using microorganism has been promoted and enhanced by two different approaches, such as modification of the metabolic pathways of microorganism and optimization of culture medium conditions to synthesize specific compounds. However, research community is today focused on the development of processes and techniques for a suitable recovery of metabolites from different stages of fermentation. For this purpose, the use of organic solvents has been the most common approach for the recovery of specific target compounds according to the solvent affinity. Additionally, these techniques also require the implementation of unit processes to obtain better recovery rates; it means that solvent extraction methods need the implementation of additional steps to recover the solvents used, which may involve the increase of final costs in the production process. For this reason, researchers have started to consider membrane-based technologies (e.g. microfiltration [MF], ultrafiltration [UF], and nanofiltration [NF]), as an alternative for the recovery of metabolites from fermentation broths. Therefore, the objective of this paper is to provide an overview of the current findings of the recovery of metabolites from fermentation broths by means of pressuredriven membrane processes. Particular attention will be paid to relevant data, analyzing and discussing according to the membrane features, metabolite properties, and some other phenomena that influence in the separation.Moreover, a framework of the application of the MF, UF, and NF processes in solutes recovery is addressed. Finally, some fundamentals of these processes are also given.

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“…According to the newest reports of Patra et al (2018), the species Panax ginseng is the most widely cultivated and marketed species among phytochemicals-rich plants all over the world. This plant is distributed across approx.…”

mentioning

confidence: 99%

“…The worldwide ginseng production is estimated at more than 80,000 t. In 2015, the ginseng's global market of dietary supplements was valued at over US$ 123 billion. Moreover, it is assumed that the market's demand for ginseng will continue to remain strong throughout the 2016-2026 forecast period (Patra et al 2018). Nowadays, there is the highest demand for the powdered form of ginseng, due to its extensive consumption as an energy booster.…”

mentioning

confidence: 99%

Saponins in Food

Oleszek

2019

Handbook of Dietary Phytochemicals

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Saponins belong to the group of plant glycosides widely distributed in more than 100 families of both wild and cultivated plants and in some marine organisms. They consist of the steroidal or triterpene hydrophobic aglycone and one to three sugar chains (hydrophilic part) attached by ester or ether linkage. Based on number of chains attached to the aglycone, they can be categorized as monodesmosides, bidesmosides, or tridesmosides. To this group of compounds, the glycoalkaloids are also included. Some saponins may contain in their structures (in aglycone part or in sugar chain) glucuronic acid, what makes them acidic. A big number of structurally divergent compounds have been described. Their structures and concertation can be different even in the organs (roots, rhizomes, stems, bark, leaves, seeds, and fruits) of the same plant species. Depending on the structure, they express different biological activities. Triterpenoid saponins can be found in many legumes (alfalfa, soybean, chickpeas, beans, peanuts, broad beans, kidney beans, and lentils), ginseng roots, sunflower seeds, horse chestnut, liquorice roots, spinach leaves, tea leaves, quillaja bark, quinoa seeds, sugar beet, or alliums species. Steroidal saponins can be found in oats, Yucca, tomato seeds, yam, fenugreek seeds, ginseng roots, asparagus, aubergine, or capsicum peppers. Glycoalkaloids are characteristic compounds mostly for Soalanaceae species. In general these compounds show no or little toxicity and do not seem to be of hazard for consumers. Depending on the structure, they express different biological activities. In general, saponins have been related to immunostimulatory, hypocholesterolemic, antitumor, anti-inflammatory, antibacterial, antiviral, antifungal, and antiparasitic activities. The major feature of these compounds is their sterol affinity, which seem to be responsible for most of activities they express. When consumed they may provide different health benefits, out of which cholesterol reducing activity is most pronounced.

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Selected commercial plants: A review of extraction and isolation of bioactive compounds and their pharmacological market value

Cited by 102 publications

References 200 publications

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Innovative Extraction Techniques Using Deep Eutectic Solvents and Analytical Methods for the Isolation and Characterization of Natural Bioactive Compounds from Plant Material

Metabolites recovery from fermentation broths via pressure‐driven membrane processes

Saponins in Food

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