Segmental transcutaneous measurements of PO2 in patients requiring below-the-knee amputation for peripheral vascular insufficiency.

Burgess, Ernest M.; Matsen, F A; Wyss, C R; Simmons, Charles W.

doi:10.2106/00004623-198264030-00007

Cited by 117 publications

(27 citation statements)

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“…TCPO 2 >30 mmHg was used as an entry criterion for the trial. Poor ulcer healing has been associated with TCPO 2 levels < 2 0 -4 0 mmHg (20)(21)(22). A TCPO 2 of 30 mmHg was chosen as a midrange level suggesting adequate oxygenation for ulcer healing to occur.…”

Section: Days Of Treatmentmentioning

confidence: 99%

Randomized Prospective Double-Blind Trial in Healing Chronic Diabetic Foot Ulcers: CT-102 activated platelet supernatant, topical versus placebo

et al. 1992

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Section: Days Of Treatmentmentioning

confidence: 99%

Randomized Prospective Double-Blind Trial in Healing Chronic Diabetic Foot Ulcers: CT-102 activated platelet supernatant, topical versus placebo

et al. 1992

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“…From a rehabilitation perspective (with a few exceptions), it is desirable to have a more distal level of limb amputation. Lower level of amputation reduces the energy consumption required for ambulation ( Figures 5 and 6) and the need for a more functional prosthesis [10,11]. For example, the energy required to walk after a transfemoral (TF) amputation is much greater than that required after a transtibial amputation [8,12].…”

Section: Pre-surgical Biomechanical Considerations Affecting Amputeementioning

confidence: 99%

“…Burgess et al [10] Presence of popliteal pulse The presence of pulsations in the popliteal artery has been associated with an 89% healing rate of TT patients.…”

Section: Clinical Relevance Referencementioning

confidence: 99%

Lower-extremity amputations in patients with diabetes: pre- and post-surgical decisions related to successful rehabilitation

Davis

Kuznicki

Praveen

et al. 2004

Diabetes Metab. Res. Rev.

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What is generally recognized is that there are disparities in the rates of amputation for type 1 versus type 2 diabetic patients, for different ethnic groups and for patients with multiple co-morbidities. However, with advances in surgical techniques and with modern prosthetics, all categories of patients are benefiting from surgeries in which a longer residual limb can be kept (within surgical constraints related to proper wound healing), and where appropriate biomechanical considerations are taken into account.

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“…As with other susceptible patient groups, the measurement of tissue viability is required, which is dependent upon the adequate supply of nutrients from the circulation. Non-invasive assessments of transcutaneous gas tensions have been employed to assess tissue viability in several clinical conditions where perfusion pressures are compromised (8,9). These studies have indicated a threshold level of transcutaneous oxygen tension (T,Po,) of greater than 5.3 kPa (40 mmHg) to ensure adequate healing on amputation stumps and on feet with ischaemic lesions.…”

Section: Tissue Viabilitymentioning

confidence: 99%

Transcutaneous Gas Tensions in the Sacrum during the Acute Phase of Spinal Cord Injury

Bogie

Nuseibeh

Bader

1992

Proc Inst Mech Eng H

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The first few months following injury to the spinal cord requires constant care of the subject if tissue breakdown is to be avoided. The management of acute traumatic cases involves complete bedrest in a supine position with appropriately positioned pillows to minimize trauma to the bone prominences. This study assesses the effectiveness of the management procedure in terms of the tissue response at the sacrum of 15 acute spinal cord injured subjects. The measurement of mean interface pressures during a representative period of recumbency was performed and these were related to changes in transcutaneous gas tensions (TcPO2 and TcPCO2), which are reliable indices of tissue viability. A series of six variables was established which were compared to each other using non-parametric statistical analyses. It was shown that this group of subjects demonstrated a normal mechanism whereby the level of carbon dioxide was able to control the local vascular tone. The results also suggested that the practice of gapping at the sacrum should be revised to reduce mean sacral pressures and minimize the possibility of tissue breakdown, the risk of which is constant throughout the first three months following injury.

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Segmental transcutaneous measurements of PO2 in patients requiring below-the-knee amputation for peripheral vascular insufficiency.

Cited by 117 publications

References 0 publications

Randomized Prospective Double-Blind Trial in Healing Chronic Diabetic Foot Ulcers: CT-102 activated platelet supernatant, topical versus placebo

Randomized Prospective Double-Blind Trial in Healing Chronic Diabetic Foot Ulcers: CT-102 activated platelet supernatant, topical versus placebo

Lower-extremity amputations in patients with diabetes: pre- and post-surgical decisions related to successful rehabilitation

Transcutaneous Gas Tensions in the Sacrum during the Acute Phase of Spinal Cord Injury

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