Secretory breast carcinoma with metastatic sentinel lymph node

Vieni, Salvatore; Cabibi, Daniela; Cipolla, Calogero; Fricano, Salvatore; Graceffa, Giuseppa; Latteri, M

doi:10.1186/1477-7819-4-88

Cited by 43 publications

(45 citation statements)

References 22 publications

(29 reference statements)

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“…However, subsequent reports suggested that only a third of the published cases occurred in children, and the median age for patients with an SBC is 25 years 1 – 26. SBCs account for <1% of invasive breast carcinomas and are characterised clinically by late local recurrences and prolonged survival even with lymph node involvement 5 7 10 – 12.…”

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confidence: 99%

Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication

Lambros

Tan

Jones

et al. 2009

Journal of Clinical Pathology

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To the best of our knowledge, this is the first time a carcinoma has been shown to harbour a duplication of the ETV6-NTRK3 translocation. The presence of an additional copy of the derivative chromosome der(15)t(12;15) coupled with deletion of the other derivative der(12)t(12;15) in the modal population of cancer cells suggests that this was either an early phenomenon or conferred additional growth advantage on neoplastic cells.

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mentioning

confidence: 99%

Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication

Lambros

Tan

Jones

et al. 2009

Journal of Clinical Pathology

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“…Many authors report frequency of local relapse after simple surgical removal of neoplasia [6]. Whenever possible, breast bud should be preserved in prepubertal girls by wide local excision.…”

Section: Discussionmentioning

confidence: 99%

“…Postoperative radiotherapy is useful to local control of the disease if conservative surgery performed in adults. However, this is not advised in children with possible secondary effects such as fibrosis of lung, rib damage and consequent asymmetry of rib cage [6]. Radiotherapy for local recurrence in a mastectomy scar was used in a 4-year-old girl successfully who was disease free for 11 years after the initial diagnosis [3].…”

Section: Discussionmentioning

confidence: 99%

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Secretory breast carcinoma in a 6-year-old girl: mastectomy with sentinel lymph node dissection

et al. 2015

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Secretory breast carcinoma (SBC) is a rare type of breast neoplasia that was originally described in children. SBC is an indolent breast tumor with good clinical outcome and rare systemic involvement. Since, majority of studies concerning pediatric SBC have been case reports, it has been difficult to clearly elucidate the characteristics and optimal treatment strategies for SBC in children. Although treatment recommendations vary, surgical excision is the primary mode of treatment. Also, necessity of axillary and/or sentinel lymph node dissection is another matter of discussion in children. We report a 6-year-old girl who was diagnosed as SBC was reported to discuss the use of mastectomy with sentinel lymph node dissection in the treatment of this rare tumor in children.

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“…OALib Journal of "juvenile carcinoma" [1] [2]. Despite the low frequency, SBC elicits pathologic interest because of their unique morphology and excellent prognosis.…”

Section: /5mentioning

confidence: 99%

Secretory Breast Carcinoma, a Case Report and Literature Review

Laajili¹,

Salem²,

Zaidi³

et al. 2017

OALib

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Secretory breast carcinoma (SBC) is a very rare subtype of breast carcinoma that reported mostly in young women, with a median age of 25 years. Despite the low frequency, SBC elicits pathologic interest because of their unique morphology and excellent prognosis. Authors report a 23-year-old woman presented with a nodule in retro areolar region of her right breast. Microbiopsic examination revealed neoplastic tissue. Pathological examination of tumor revealed SBC. This tumor is morphologically characterized by the presence of abundant eosinophilic secretions in intracellular vacuoles and intercellular spaces. The objective of this paper is to review the epidemiological, clinical, paraclinical and therapeutic aspects of SBC from a case report and literature review.

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Secretory breast carcinoma with metastatic sentinel lymph node

Cited by 43 publications

References 22 publications

Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication

Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication

Secretory breast carcinoma in a 6-year-old girl: mastectomy with sentinel lymph node dissection

Secretory Breast Carcinoma, a Case Report and Literature Review

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