2015
DOI: 10.1007/s00383-015-3721-0
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Abstract: Secretory breast carcinoma (SBC) is a rare type of breast neoplasia that was originally described in children. SBC is an indolent breast tumor with good clinical outcome and rare systemic involvement. Since, majority of studies concerning pediatric SBC have been case reports, it has been difficult to clearly elucidate the characteristics and optimal treatment strategies for SBC in children. Although treatment recommendations vary, surgical excision is the primary mode of treatment. Also, necessity of axillary … Show more

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Cited by 15 publications
(31 citation statements)
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“…The primary tumor commonly presents as a slow growing, painless, mobile, palpable well‐circumscribed mass located in the left and right breast with equal frequency . It is more common in the upper outer quadrants in adults, whereas in younger patients the location is commonly described in case reports as subareolar, as is the case presented herein. This is likely due to the smaller relative size of the breast mound in younger patients deep to the NAC.…”
Section: Literature Review and Discussionmentioning
confidence: 61%
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“…The primary tumor commonly presents as a slow growing, painless, mobile, palpable well‐circumscribed mass located in the left and right breast with equal frequency . It is more common in the upper outer quadrants in adults, whereas in younger patients the location is commonly described in case reports as subareolar, as is the case presented herein. This is likely due to the smaller relative size of the breast mound in younger patients deep to the NAC.…”
Section: Literature Review and Discussionmentioning
confidence: 61%
“…Ultrasonography is preferable, especially in younger patients, given its quick, noninvasive, radiation‐sparing nature. Fine‐needle aspiration (FNA) biopsy of the mass can aid in the diagnosis of SBC, however, it has not routinely been done in adults or children with these imaging findings and many are taken directly to the operating room for excisional biopsy initially to obtain the diagnosis, with subsequent return to the OR for definitive treatment. In efforts to save a trip to the OR, we recommend utilizing an FNA biopsy or better yet, a core needle biopsy, with the addition of mild sedation for children, to first obtain the diagnosis, then proceed to OR for one definitive surgical procedure.…”
Section: Literature Review and Discussionmentioning
confidence: 99%
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“…Due to the rarity of SCB, the e cacy of neoadjuvant chemotherapy, adjuvant chemotherapy and postoperative radiotherapy has not been con rmed by enough clinical studies to date. Soyar et al (30) suggested that patients with primary tumors > 2 cm in diameter should receive axillary lymph node dissection, combined with radiation therapy and chemotherapy. Although previous studies have reported non-response of SCB to chemotherapy (31), in a case report published in 2015, a 13-year-old male patient diagnosed with SCB with metastasis to a single lymph node received chemotherapy with adriamycin and cyclophosphamide for 6 cycles after radical mastectomy, and he has remained disease-free over a 10year follow-up.…”
Section: Discussionmentioning
confidence: 99%