2014
DOI: 10.1021/jf500054f
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Abstract: Two new metabolites, an α-pyridone derivative, 3-hydroxy-2-methoxy-5-methylpyridin-2(1H)-one (1), and a ceramide derivative, 3-hydroxy-N-(1-hydroxy-3-methylpentan-2-yl)-5-oxohexanamide (2), and a new natural product, 3-hydroxy-N-(1-hydroxy-4-methylpentan-2-yl)-5-oxohexanamide (3), along with 15 known compounds including chaetoglobosin C (7) and chaetoglobosin F (8) were isolated from the solid culture of the endophytic fungus Botryosphaeria dothidea KJ-1, collected from the stems of white cedar (Melia azedarac… Show more

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Cited by 168 publications
(152 citation statements)
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“…Endophytes that inhabit medicinal plants exhibit potent biological activity, such as antioxidant, antimalarial, antimicrobial, and anticancer activities (Strobel et al, 2004;Xiao et al, 2014). In the current study, endophytes isolated from medicinal plants were assessed for their antioxidant activity.…”
Section: Discussionmentioning
confidence: 99%
“…Endophytes that inhabit medicinal plants exhibit potent biological activity, such as antioxidant, antimalarial, antimicrobial, and anticancer activities (Strobel et al, 2004;Xiao et al, 2014). In the current study, endophytes isolated from medicinal plants were assessed for their antioxidant activity.…”
Section: Discussionmentioning
confidence: 99%
“…The production of secondary metabolites, such as antibiotics, also play an important role and they have been extensively investigated. Some of these studies not only isolated microorganisms with the ability to control pathogens, but also identified the molecules responsible for such action, as observed in the studies performed by Vinale et al (2006) and Xiao et al (2014). They obtained new molecules with activity against Rhizoctonia solani, Pythium ultimum, Gaeumannomyces graminis var.…”
Section: Introductionmentioning
confidence: 93%
“…Other genera such as Botryosphaeria sp., Bipolaris sp., Cylindrocarpon sp., Cylindrotrichum sp., Lasiodiplodia sp., Monodictys sp., and Myrothecium sp. were also reported for their endophytic occurrence in medicinal plants, though not as often as the previously mentioned dominant genera (Gao et al 2014;Sultan et al 2014;Yang et al 2014). Gliocladium spp., isolated as endophytes from Eucryphia cordifolia, were reported to produce low molecular weight volatile hydrocarbons (Strobel et al 2008).…”
Section: Discussionmentioning
confidence: 84%