The effects of seven (prenyl-and methoxy-) derivatives of cinnamic acid (0.1 mM) on the kinetics of lipid (sunflower oil triacylglycerols, TGSO) bulk phase oxidation at 80°C have been compared. Synthesis of prenyl cinnamic acid derivatives: 3-prenyl-4-hydroxy-cinnamic acid (PHC), 3,5-diprenyl-4-hydroxy-cinnamic acid (DPHC), 2,2-dimethyl-6-carboxy-ethenyl-2H-benzopyran (DMCB), 2,2-dimethyl-6-carboxy-ethenyl-8-prenyl-2H-benzopyran (DCEPB) present in Brazilian propolis has been performed. The monoprenyl derivative (PHC) has been found to exert a higher antioxidant activity as compared to the diprenyl derivative (DPHC). However, cinnamic acid derivatives DMCB and DCEPB have caused no change in the kinetics of TGSO oxidation. The results obtained have been compared with those on related compounds containing a cinnamic acid moiety as a structural feature, such as 4-hydroxy-cinnamic (p-coumaric), 3-methoxy-4-hydroxy-cinnamic (ferulic) and 3,5-dimethoxy-4-hydroxy-cinnamic (sinapic) acids, as well as with data on butylated hydroxytoluene (BHT) and α-tocopherol (α-Toc). PHC has shown a stronger antioxidant efficiency than BHT, p-coumaric and ferulic acid, but a weaker antioxidant efficiency than α-Toc and sinapic acid. The observed antioxidant effect of DPHC was stronger than that of p-coumaric and ferulic acids and weaker than that of α-Toc, BHT and sinapic acid.