Secondary Metabolites from Asphodelus aestivus

Abstract

Together with ten well known compounds, the quinic acid derivative chlorogenic acid, the nucleoside adenosine, two amino acids, tryptophan and phenylalanine, the anthraquinone derivatives, aloemodin, aloemodin acetate and chyrosphanol 1-O-gentiobioside, the flavon C-glycosides, isovitexin, isoorientin and isoorientin 4’-O-β -glucopyranoside, as well as two new acylated isoorientin derivatives, 6”-O-(malonyl)-isoorientin and 6”-O-[(S)-3-hydroxy-3-methylglutaroyl]-isoorientin, were isolated from the water soluble part of the methanolic extract of the fresh leaves of Asphodelus aestivus. All compounds were structurally identified by spectroscopic methods, including UV, MS, and NMR (1D and 2D) spectroscopy. Among the compounds isolated, chlorogenic acid and isoorientin were found to be the main compounds of the methanolic extract.

Bioguided Identification of Active Antimicrobial Compounds from Asphodelus bento-rainhae and Asphodelus macrocarpus Root Tubers

“…Chlorogenic acid was detected in the leaf extract of Asphodelus aestivus Brot. [ 28 ] and caffeic acid was reported from the flower extract of A. ramosus [ 29 ]. 7′-(chrysophanol-4-yl)-chrysophanol-10′- C -beta- D -xylopyranosyl-anthrone was also reported from the root tuber extract of A. ramosus [ 30 ].…”

Secondary metabolites from Scabiosa atropurpurea and their antioxidant and xanthine oxidase inhibitory activities

“…EtOAc and H2O subextracts were subjected to various chromatographic separations to afford ten secondary metabolites including two secoiridoid glycosides (1 and 2), six flavonoids (3)(4)(5)(6)(7)(8) and two caffeoylquinic acid derivatives (9 and 10) (Figure 1). The isolates were identified as lonicejaposide I (1) [23], secologanin dimethyl acetal (2) [24], isoorientin (3) [25], hesperidin (4) [26] [30], chlorogenic acid (9) and 3,5-dicaffeoylquinic acid (10) [31] by comparing their spectroscopic data with literature values. In previous studies, compounds 6 and 10 were characterized by LC-MS analyses from the extracts of S. atropurpureawhile compounds 5 and 9 were recently detected in this species [10,11,32].…”

LC-ESI/MS-Phytochemical Profiling with Antioxidant, Antibacterial, Antifungal, Antiviral and In Silico Pharmacological Properties of Algerian Asphodelus tenuifolius (Cav.) Organic Extracts

“…It reaches its maximum diversity in the Iberian Peninsula and Northwest Africa [ 2 ]. Asphodelus species were found to contain several secondary metabolites such as flavonoids [ 3 , 4 ], anthraquinones [ 5 , 6 ], phenolic acids [ 7 , 8 ], triterpenes [ 9 , 10 ], fatty acids [ 11 ] and naphthalene derivatives [ 12 ]. Different ethnomedical uses were ascribed to Asphodelus species, including Asphodelus tenuifolius Cav., known as onion weed [ 13 ], native to the Mediterranean region, which is used traditionally not only as a vegetable but also for colds, hemorrhoids, rheumatic pain, diuretic agent and wound healing [ 14 ].…”