Secondary Metabolites from Asphodelus aestivus

Çalış, İhsan; Birincioğlu, S. Serap; Kırmızıbekmez, Hasan; Pfeiffer, Bernhard; Heilmann, Joerg

doi:10.1002/chin.200709188

Cited by 3 publications

(3 citation statements)

References 10 publications

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“…The bulbs and roots of A. microcarpus are used as an antimicrobial agent. [6][7][8][9][10][11] The leaves of A. aestivus Brot. are commonly consumed cooked as a vegetable dish in Turkey, where it is known as "ciris otu."…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and radical scavenging activities of Asphodelus aestivus Brot. extracts

Peksel

Imamoglu

Kiymaz

et al. 2013

International Journal of Food Properties

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Asphodelus aestivusBrot. is a common spring-flowering geophyte encountered on the Marmara, Aegean, and Mediterrenean coasts of Turkey, which has been utilized traditionally for culinary and medicinal purposes. In the present study, different antioxidant tests were employed in order to evaluate the antioxidant activities of methanolic and acetone extracts of A. aestivus Brot. leaves. In addition, the results were compared with natural and synthetic antioxidants. The levels of total flavonoid, total chlorophyll, and total carotenoid contents of the extracts were also determined. Both extracts showed good total flavonoid content, inhibited lipid peroxidation, and showed radical scavenging activities.

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Section: Introductionmentioning

confidence: 99%

Antioxidant and radical scavenging activities of Asphodelus aestivus Brot. extracts

Peksel

Imamoglu

Kiymaz

et al. 2013

International Journal of Food Properties

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“…The chemical structures of the compounds were identified as harpagide (1), 8-O-acetylharpagide (2) (Calis et al 1992), cis-melilotoside (3), trans-melilotoside (4) (Vasänge et al 1997), dihydromelilotoside (5) (Ranarivalo et al 1990) verbascoside (6) (Sticher and Lahloub 1982), galactosylmartynoside (7) (Takasaki et al 1998) and isoorientin (8) (Calis et al 2006) by comparison of their 1D and 2D NMR and MS data with those published previously. Table 1 displays the antiprotozoal activities of the isolated compounds from A. laxmannii.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites

Atay

Kırmızıbekmez

Kaiser

et al. 2016

Pharmaceutical Biology

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Context Some Ajuga L. (Lamiaceae) species are traditionally used for the treatment of malaria, as well as fever, which is a common symptom of many parasitic diseases. Objective In the continuation of our studies on the identification of antiprotozoal secondary metabolites of Turkish Lamiaceae species, we have investigated the aerial parts of Ajuga laxmannii. Materials and methods The aerial parts of A. laxmannii were extracted with MeOH. The H 2 O subextract was subjected to polyamide, C 18 -MPLC and SiO 2 CCs to yield eight metabolites. The structures of the isolates were elucidated by NMR spectroscopy and MS analyses. The extract, subextracts as well as the isolates were tested for their in vitro antiprotozoal activities against Plasmodium falciparum, Trypanasoma brucei rhodesiense, T. cruzi and Leishmania donovani at concentrations of 90-0.123 mg/mL. Results Two iridoid glycosides harpagide (1) and 8-O-acetylharpagide (2), three o-coumaric acid derivatives cis-melilotoside (3), trans-melilotoside (4) and dihydromelilotoside (5), two phenylethanoid glycosides verbascoside (6) and galactosylmartynoside (7) and a flavone-C-glycoside, isoorientin (8) were isolated. Many compounds showed moderate to good antiparasitic activity, with isoorientin (8) displaying the most significant antimalarial potential (an IC 50 value of 9.7 mg/mL). Discussion and conclusion This is the first report on the antiprotozoal evaluation of A. laxmannii extracts and isolates. Furthermore, isoorientin and dihydromelilotoside are being reported for the first time from the genus Ajuga.ARTICLE HISTORY

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“…A severe neurological syndrome accompanied by intense neuronal pigmentation in sheep in Turkey was observed after the ingestion of summer asphodel (Calis et al, 2006). The high silicon (Si) content of mature leaves contributes to its unpalatability, whereas the tubers are protected from herbivores through the accumulation of defense substances, such as alkaloids that are harmful to sheep and goats (Rhizopoulou et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

EFFECTS OF SUPPRESSION APPLICATIONS ON SUMMER ASPHODEL (Asphodelus aestivus Brot.) DENSITY, BOTANICAL COMPOSITION, FORAGE YIELD AND QUALITY OF AEGEAN RANGELANDS

Sürmen

Kara

2022

Turkish Journal of Field Crops

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Summer asphodel (Asphodelus aestivus Roth.) has an underground storage organ that enables the plant to survive extreme conditions and contains alkaloids that are toxic for the livestock in rangelands. For this reason, the experiment was carried out in the rangeland of Aydin province (Turkey) in order to determine the most effective methods of weed management where there is an increase in summer asphodel (Asphodelus aestivus Roth.) population. In the study, the effects of 8 different control methods (control, mowing, fertilization, paraquat, glyphosate, 2,4-D, 2,4-D + Picloram, removal from the soil) on yield, quality and botanical composition were investigated. Result of the findings in this study shows that the grasses increased more in vegetation. The highest values of hay yield were observed in paraquat and fertilization applications. High values of crude protein yield were found in fertilization and removal from soil applications. The lowest population of summer asphodel (Asphodelus aestivus Roth.) was obtained removal from soil applications. Together with these results, removal from the soil, fertilization, paraquat and glyphosate applications come to the fore. However, due to the high workforce, it is important to choose an application considering the size of the rangeland and the population of the indicator weed species.

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Secondary Metabolites from Asphodelus aestivus

Cited by 3 publications

References 10 publications

Antioxidant and radical scavenging activities of Asphodelus aestivus Brot. extracts

Antioxidant and radical scavenging activities of Asphodelus aestivus Brot. extracts

Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites

EFFECTS OF SUPPRESSION APPLICATIONS ON SUMMER ASPHODEL (Asphodelus aestivus Brot.) DENSITY, BOTANICAL COMPOSITION, FORAGE YIELD AND QUALITY OF AEGEAN RANGELANDS

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