1996
DOI: 10.1289/ehp.96104866
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Second moment method for evaluating human health risks from groundwater contaminated by trichloroethylene.

Abstract: Pollutants in groundwater aquifers may constitute a significant human health risk. A large variation in response may result among human populations experiencing the same level and duration of exposure to pollutants. Variability in response, as a result of exposure to a carcinogenic contaminant such as trichloroethylene (TCE), can be represented by a distribution function of safe doses. Spatial variability in aquifer characteristics and contaminant transport parameters requires the use of stochastic transport m… Show more

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Cited by 8 publications
(3 citation statements)
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References 7 publications
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“…Letting fr(r) and fc(c) define the distribution of safe doses and the distribution of contaminant concentrations, respectively, the probability of the remediation method not achieving reductions in contaminant concentrations that are below the prescribed low cancer risk is defined by the convolution integral as (132) 00 Pf = JF7(C)f,(C)dc 0 [27] where Fr(C) is the cumulative distribution function of fr(R) evaluated at C. Equation incorporate exposure information into health risk assessment. The second moment method was used to calculate cancer risk contours for a contaminated aquifer at Hill Air Force Base, Utah (133). In this study, contaminant plume concentrations for trichloroethylene were incorporated into the risk assessment process to produce cancer risk contours for the contaminated aquifer.…”
Section: Evaluating Remediation Technology Performancementioning
confidence: 99%
“…Letting fr(r) and fc(c) define the distribution of safe doses and the distribution of contaminant concentrations, respectively, the probability of the remediation method not achieving reductions in contaminant concentrations that are below the prescribed low cancer risk is defined by the convolution integral as (132) 00 Pf = JF7(C)f,(C)dc 0 [27] where Fr(C) is the cumulative distribution function of fr(R) evaluated at C. Equation incorporate exposure information into health risk assessment. The second moment method was used to calculate cancer risk contours for a contaminated aquifer at Hill Air Force Base, Utah (133). In this study, contaminant plume concentrations for trichloroethylene were incorporated into the risk assessment process to produce cancer risk contours for the contaminated aquifer.…”
Section: Evaluating Remediation Technology Performancementioning
confidence: 99%
“…5 Due to its toxicity and carcinogenic effect, exposure to TCE may result in adverse health effects. [6][7][8][9] For example, acute exposures to TCE at doses exceeding 250 ppm can impair the central nervous system, whilst long-term exposure is thought to induce hepatotoxicity, nephrotoxicity and neurotoxicity. 10 Psychomotor impairment was noticed aer inhalation exposure to 5400 mg m À3 (1000 ppm) for 2 h in work place conditions.…”
Section: Introductionmentioning
confidence: 99%
“…8 Furthermore, TCE was confirmed to be a carcinogenic material in many medical investigations. [9][10][11] Therefore, to detect and monitor TCE concentration in order to protect people health is very important in the working environment.…”
mentioning
confidence: 99%