SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way

Zhu, Qing; Wan, Nengbin; Deng, Hongwu; Lu, Lingli; Zhang, Yi; He, Xiao; Liu, Hao; He, Ying

doi:10.1016/j.yexcr.2022.113161

Cited by 2 publications

(1 citation statement)

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“…The antiviral signal transduction pathway mediated by Retinoic acidinducible gene I (RIG-I) can be negatively regulated by the protein encoded by SEC14L1, through inhibition of interaction between RIG-I and downstream effectors [15]. Moreover, both human SEC14L2 and SEC14L3 exhibit an active role in suppressing tumor growth by exerting anti-proliferative effects [16,17].…”

Section: Pitps In Animalsmentioning

confidence: 99%

Identification and Expression Analysis of Phosphatidylinositol Transfer Proteins Genes in Rice

Pei

Xie

Peng

et al. 2023

Plants

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The family of phosphatidylinositol transfer proteins (PITPs) is able to bind specific lipids to carry out various biological functions throughout different stages of plant life. But the function of PITPs in rice plant is unclear. In this study, 30 PITPs were identified from rice genome, which showed differences in physicochemical properties, gene structure, conservation domains, and subcellular localization. The promoter region of the OsPITPs genes included at least one type of hormone response element, such as methyl jasmonate (Me JA) and salicylic acid (SA). Furthermore, the expression level of OsML-1, OsSEC14-3, OsSEC14-4, OsSEC14-15, and OsSEC14-19 genes were significantly affected by infection of rice blast fungus Magnaporthe oryzae. Based on these findings, it is possible that OsPITPs may be involved in rice innate immunity in response to M. oryzae infection through the Me JA and SA pathway.

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Section: Pitps In Animalsmentioning

confidence: 99%