Sebaceous carcinoma arising from sebaceoma

Lee, Da Woon; Kwak, Si Hyun; Kim, Jun Hyuk; Byeon, Je Yeon; Lee, Hyun Joo; Choi, Hwan Jun

doi:10.7181/acfs.2021.00059

Cited by 7 publications

(8 citation statements)

References 18 publications

(23 reference statements)

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“…The NSJ in our patient also included areas resembling sebaceoma and sebaceous adenoma. Sebaceoma is composed of a random admixture of germinative basaloid cells and mature sebocytes lacking an organized lobular architecture [ 18 ]. Sebaceous adenoma comprises irregular sebaceous lobules with a rim of basaloid cells peripherally and mature sebocytes centrally [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Development of seven secondary neoplasms in a nevus sebaceous: a case report and literature review

Kuo

Lin

Tsai

2022

Arch Craniofac Surg

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Nevus sebaceous of Jadassohn is a congenital cutaneous hamartoma with epidermal, sebaceous, follicular, and apocrine structures that usually appears at birth or in early childhood. It has the potential to generate a variety of secondary neoplasms of different lineages, and the risk increases with patient age. Although multiple neoplasms may occasionally arise within the same lesion, the coexistence of more than five secondary tumors is extremely rare. Here we report a case of seven secondary tumors including syringocystadenoma papilliferum, desmoplastic trichilemmoma, sebaceoma, trichoblastoma, pigmented trichoblastoma, sebaceous adenoma, and tumor of follicular infundibulum arising within a nevus sebaceous. The complete diagnosis relies on the histopathological analysis of multipoint biopsies and delicate pathological sections.

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Section: Discussionmentioning

confidence: 99%

Development of seven secondary neoplasms in a nevus sebaceous: a case report and literature review

Kuo

Lin

Tsai

2022

Arch Craniofac Surg

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“…11 Predomina en mujeres en edad avanzada, con media de edad de 70 años, 12 en quienes se manifiesta como lesión de novo o como tumor secundario asociado a nevo sebáceo o queratosis seborreica, o también puede formar parte de alguna genodermatosis como el síndrome de Muir-Torre. 13,14 El sebaceoma predomina en zonas donde abundan las glándulas sebáceas como piel cabelluda y cara; no obstante, se han reportado casos en cuello, tronco y extremidades. 2,14 En general son lesiones únicas (rara vez múltiples) de crecimiento lento, asintomáticas, que se manifiestan como neoformaciones hemiesféricas y bien delimitadas, o bien, de aspecto nodular o en placa.…”

Section: Sebaceomaunclassified

“…La superficie suele ser verrugosa y puede estar ulcerada. 12,13 En la dermatoscopía se observan áreas ovoides amarillo-rosadas que corresponden a conglomerados de células con diferenciación sebácea, así como estructuras vasculares similares a los vasos arborescentes del carcinoma basocelular, e incluso áreas de ulceración. 15,16 El estudio histopatológico establece el diagnóstico definitivo.…”

Section: Sebaceomaunclassified

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Tumores con diferenciación sebácea. Comunicación de tres casos y revisión de la literatura

Ortiz-Lobato¹,

Navarrete-Franco²,

González-González³

et al. 2022

Revista Del Centro Dermatológico Pascua

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Caso clínico RESUMENLos tumores con diferenciación sebácea son un grupo de neoformaciones anexiales poco frecuentes. Suelen manifestarse en adultos mayores, comprometiendo cabeza y cuello. Actualmente, se les clasifica en tres grandes grupos: adenoma sebáceo, sebaceoma y carcinoma sebáceo. En este artículo se comunican tres casos de pacientes con tumores de estirpe sebácea que se presentaron a diferentes edades de la vida.

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“…Sebaceous carcinoma is a malignant neoplasm that usually arises in the sebaceous glands of the eyelids, especially from the meibomian glands of the upper eyelid; the tarsal conjunctiva is the most common site [ 1 , 2 ]. It usually presents as a painless yellow mass with no distinctive clinical features [ 2 , 3 ]. The prognosis of sebaceous carcinoma is one of the worst compared to other malignancies occurring in the eyelid, and it accounts for a considerable proportion of malignant eyelid tumors in Asia [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Upper eyelid reconstruction using a combination of a nasal septal chondromucosal graft and a Fricke flap: a case report

Lee

Woo

Shin

et al. 2021

Arch Craniofac Surg

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Sebaceous carcinoma is a malignant neoplasm that usually arises in the sebaceous glands of the eyelids. Its pathogenesis is unknown; however, irradiation history, immunosuppression, and use of diuretics are known risk factors. The mainstay of treatment for sebaceous carcinoma of the eyelid is wide surgical resection with a safety margin of 5 to 6 mm, which often results in full-thickness defects. The reconstruction of a full-thickness defect of the eyelid should be approached using a three-lamella method: a mucosal component replacing the conjunctiva, a cartilage component for the tarsal plate, and a flap or skin graft for the skin of the eyelid. In this case, a fullthickness defect of the upper eyelid was reconstructed after tumor removal using a combination of a nasal septum chondromucosal composite graft and a forehead transposition flap, also known as a “Fricke flap.” The flap was designed to include a line of the eyebrow on the lower margin of the flap to replace the eyelash removed during tumor excision. The wound healed completely, without any early or late complications, and the outcome was satisfactory.

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Sebaceous carcinoma arising from sebaceoma

Cited by 7 publications

References 18 publications

Development of seven secondary neoplasms in a nevus sebaceous: a case report and literature review

Development of seven secondary neoplasms in a nevus sebaceous: a case report and literature review

Tumores con diferenciación sebácea. Comunicación de tres casos y revisión de la literatura

Upper eyelid reconstruction using a combination of a nasal septal chondromucosal graft and a Fricke flap: a case report

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