Sebaceous adenoma of the submandibular gland : a case report

Zare-Mahmoodabadi, Reza; Salehinejad, Jahanshah; Saghafi, Shadi; Ghazi, Narges; Mahmoudi, Parviz; Harraji, Afshin

doi:10.2334/josnusd.51.641

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…Extraocular SGC was rare, and most cases occur in dermal of the head and neck area. Only four cases arising within submandibular area of cervical region have been reported [6,[8][9][10]. No suspicious primary lesions were identified by enhanced CT of head-to-abdomen for this patient.…”

Section: Discussionmentioning

confidence: 82%

“…Some posit that such tumor cells were derived from pluripotent epithelial cells [8], Boecker et al [12] elucidated the p63+ K5+ progenitor cells may be the cells of origin of the extraocular SGC, but which subpopulation preferentially targeted for SGC initiation was unknown. While others suggest they developed from malignant transformation of differentiated sebaceous cells [10].…”

Section: Discussionmentioning

confidence: 99%

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A Mass Occupied in Neck Carotid Bifurcation Territory Diagnosed Sebaceous Adenocarcinoma: A Case Report

Jiang

Jia

et al. 2022

JAMMR

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Aims: To describe a rare case presenting with pulsing mass stumbled across the right upper neck. Presentation of Case: The patient was presented to the outpatient department of ENT due to a pulsing mass stumbled across the right upper neck for half a year. Cervical enhancement CT scan was performed, which disclosed a lesion at the bifurcation of the right carotid artery and possessed insignificant blood supply. Hospitalization was arranged for a full examination, and culminating in a diagnostic resection. Discussion: This case was challenging for clinicians to differentially diagnose the placeholder at the carotid artery bifurcation, and the pathological results in this case was extremely rare and have never been reported in the literature. Extraocular SGC is strongly associated with Muir–Torre syndrome (MTS), a phenotypic variant of Lynch syndrome and results from mutations in DNA MMR genes. It suggests all patients presenting with sebaceous neoplasms should be screened for MTS. Conclusion: Our case creates a paradigm for otolaryngologists and oral and maxillofacial surgeons.

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

A Mass Occupied in Neck Carotid Bifurcation Territory Diagnosed Sebaceous Adenocarcinoma: A Case Report

Jiang

Jia

et al. 2022

JAMMR

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“…The sebaceous adenoma is a rare, benign tumor that accounts for 0.1% of all salivary gland neoplasms and slightly less than 0.5% of all salivary adenomas [12]. Slightly more than 30 cases have been reported to date [12,[15][16][17]. The mean age at initial clinical presentation is 59 years (range, 22-90 years) with a male-to-female ratio of 4:3.…”

Section: Sebaceous Lesionsmentioning

confidence: 99%

My Journey into the World of Salivary Gland Sebaceous Neoplasms

Gnepp

2012

Head and Neck Pathol

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As part of this symposium honoring Leon Barnes, the authors were asked to present the case from which they learned the most. I chose a cystic sebaceous lymphadenoma (SL) as my case presentation. This paper presents this unusual case, as well as several additional sebaceous tumors that came across my desk the first few years I was in practice. These interesting cases led me to thoroughly review the literature on sebaceous tumors of the salivary glands, resulting in several publications, the largest series of sebaceous tumors published at this time as well as a careful review of all cases in the literature. The author will also review the current and previous literature on the five types of salivary gland sebaceous tumors: sebaceous adenoma, SL (and non-sebaceous lymphadenoma), sebaceous carcinoma, sebaceous lymphadenocarcinoma, and sebaceous differentiation in other types of salivary gland lesions.

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