Sebaceoma

Troy, James L.; Ackerman, A. Bernard

doi:10.1097/00000372-198402000-00006

Cited by 145 publications

(8 citation statements)

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“…Tumors of sebaceous glands are separated into three major categories: sebaceous adenoma, basal cell carcinoma with sebaceous differentiation (sebaceous epithelioma) and sebaceous carcinoma (2). Recently, a new term, sebaceoma, has been proposed to designate a distinctive benign neoplasm of adnexal epithelium with differentiation towards sebaceous cells (6). Little or no differentiation towards features of basal or squamous cell carcinoma is found in a sebaceous gland carcinoma (4), which is a cutaneous tumor composed of circumscribed lobules of neoplastic cells, some of which have the characteristic bubbly and vacuolated cytoplasm, diagnostic for sebaceous differentiation (2).…”

Section: Discussionmentioning

confidence: 99%

Extraocular sebaceous carcinoma of the skin with visceral metastases: case report

1990

J Cutan Pathol

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Extraocular sebaceous gland carcinomas of the skin are uncommon neoplasms that may recur locally, but in contrast to their ocular counterparts infrequently metastasize. A case is reported in which a 62-year-old woman had a 1 cm scalp tumor incompletely excised. Microscopic examination revealed a sebaceous carcinoma. No further surgical treatment was performed and 31 months after diagnosis the patient presented with regional and distant metastases resulting in death. It is emphasized that extraocular sebaceous carcinoma may behave in a biologically aggressive manner, just as their counterparts arising in the ocular adnexae, and the necessity to ensure complete tumor excision is stressed.

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Section: Discussionmentioning

confidence: 99%

Extraocular sebaceous carcinoma of the skin with visceral metastases: case report

1990

J Cutan Pathol

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“…Also, high-grade development of sebocytes is not usually observed in BCE with sebaceous differentiation, which shows more random, less organized sebocytes than those seen in sebaceous adenoma (6). Sebaceoma is an entity identified by Troy and Ackerman in 1984 (7), because they preferred to avoid the vague term sebaceous "epithelioma" (8). Seba-tion and has an intimate associauon with epidermis and follicular duct epithelium.…”

Section: Sesd Was Advocated As a Disease Entity Bymentioning

confidence: 99%

Superficial Epithelioma with Sebaceous Differentiation

Kato

Ueno

1992

The Journal of Dermatology

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In 1980, Rothko, Farmer, and Zeligman first described the disease entity "Superficial epithelioma with sebaceous differentiation" as a histologically distinct, rare, benign lesion. We report here the first Japanese case fitting this description. The patient is a 38-year-old Japanese woman, who had a small, yellow, flat-topped, well-defined plaque on her right upper eyelid. Histologically, the lesion was a multilobular, superficial, dermal tumor with numerous broad attachments to the overlying epidermis. The overall configuration was a plate-like proliferation of tumor cells with well-defined borders. The tumor cells were basically uniform basaloid cells with single or clustered sebocytes in the upper part of the tumor and multiple well differentiated sebaceous lobules in the middle and lower parts of the tumor. Multiple cystic spaces were formed in the lobules. Differential diagnosis of several tumors with sebaceous differentiation is discussed.

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“…In our case the sebaceous lobules consisted of only mature seba ceous cells, whereas tumor nests in sebaceous adenoma [3], sebaceous epithelioma [3] and sebaceoma [4] are composed of both immature sebaceous cells and numer ous basaloid cells. Moreover, the hair follicle-like struc tures seen in sebaceous trichofolliculoma [5] were not ob served in our case.…”

Section: Discussionmentioning

confidence: 47%