Seasonal variations in the blood concentration of selected heavy metals in sheep and their effects on the biochemical and hematological parameters

Kováčik, Anton; Árvay, Július; Tušimová, Eva; Harangozo, Ľuboš; Zbyňovská, Katarína; Čupka, Peter; Andraščíková, Štefánia; Tomáš, Ján; Massányi, Peter

doi:10.1016/j.chemosphere.2016.10.090

Cited by 44 publications

(23 citation statements)

References 48 publications

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“…Similar fluctuations were observed in Cu concentration, which was confirmed by a positive correlation between Fe and Cu (r = 0.395). Concentration of Cu was positively correlated with Zn (r = 0.301), as was also determined in the research by El Zubeir et al (2005) in the blood of cows during lactation (Cu : Zn, r = 0.68) as well as Kovacik et al (2017) in the blood of ewes (Cu : Zn, r = 0.54).…”

Section: Discussionsupporting

confidence: 74%

“…Excessive mineral supplies pollute the environment and the chosen or default policy of mineral nutrition on a given farm leaves a "mineral footprint" (Suttle 2010). Kovacik et al (2017) found that heavy metal levels significantly contribute to environmental contamination, among which Cd, Cu, Hg, Pb and Zn are the most notable. Heavy metal contamination can be transferred to animals through direct exposure, polluted water, and crops grown on irrigated sewage, industrial effluents, vehicle emission and dirty slaughter houses (Jukna et al 2006).…”

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confidence: 99%

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Changes of macromineral and trace element concentration in the blood of ewes during lactation period

Antunović¹,

Mioč²,

Lončarić³

et al. 2021

CZECH J ANIM SCI

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The aim of the present research was to determine the changes in macromineral and trace element concentrations in ewes’ blood during the lactation period. Thirty-six Travnik pramenka ewes at the average age of 3–5 years were included in research and they were evaluated at three stages of lactation: early stage (40 ± 5 days of lactation), medium stage (80 ± 5 days of lactation) and late stage (120 ± 5 days of lactation). In ewes’ blood concentrations of macroelements (Ca, P, K, Na, Mg) and trace elements (Fe, Cu, Zn, Mo, Co, Se, Cd, As) were determined. The average concentrations of macroelements and trace elements in the blood of ewes during lactation were mostly within the reference values. Se concentrations in blood were close to the deficient ones, while concentrations of Cd and As were negligible. Concentration of Ca in blood was the lowest in the early lactation stage, higher in the late stage, and the highest in the medium stage (88.25 mg/l, 96.43 mg/l and 103.43 mg/l, respectively). A significant increase in the concentrations of Mg, Co and Cd and a significant decrease in the concentrations of Na, Fe, Cu, Zn, Mo and Se were found in blood with lactation progress. Significant correlations between the studied parameters were found, especially between macroelements (Ca : K, P : Na, K : Na, K : Mg). Positive correlations were found between some macroelements and trace elements (Ca : Co, Ca : Cd, K : Co, Na : Zn, Na : Se) and between trace elements (Fe : Cu, Cu : Zn, Cu : Mo, Cu : Se, Zn : Se, Mo : Se and Co : As). Negative correlations were found between Ca and Cu, Ca and Mo, P and Cd, K and Cu. Obtained results may help in monitoring the nutritional status and health of ewes during the lactation period, providing a clearer idea related to the supply of macrominerals and trace elements to ewes. Besides, results indicated that the environment of the farming area was not polluted with toxic elements.

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Section: Discussionsupporting

confidence: 74%

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confidence: 99%

Changes of macromineral and trace element concentration in the blood of ewes during lactation period

Antunović¹,

Mioč²,

Lončarić³

et al. 2021

CZECH J ANIM SCI

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“…Severe Cu deficiency in animals can cause obvious clinical symptoms, such as lackluster clothing hair, joint deformity, decreased reproductive capacity, neurological disorders, ataxia, anemia, even death [6,7]. Cu excesses can also cause loss of appetite, bradykinesia, hemolytic anemia and other symptoms [8][9][10]. Cu nutrient not only participates in the production of superoxide dismutase (SOD) and ceruloplasmin (CP) but also plays a key role in antioxidant system [11,12].…”

Section: Introductionmentioning

confidence: 99%

Effect of Different Copper Levels in Feed on Antioxidant Capacity in Stocking the Native Sheep in the Wumeng Prairie

Wu¹,

Xiong²,

Jian³

2021

Pol. J. Environ. Stud.

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The purpose of this research is to better understand the effect of different copper (Cu) levels of feed on the antioxidant capacity in the native sheep, solve the adverse effects of local seasonal Cu deficiency on sheep, and provide a reasonable reference for Cu supplementation. 10 healthy native sheep were selected as the control group (C group). 40 Cu-deficient native sheep were selected as tested group, and divided randomly into 4 groups (n = 10), supplied by CuSO 4 (0, 20, 40, 60 mg/kg for group I, group II, group III and group IV, respectively). The results showed that the level of Cu, hemoglobin (Hb), packed-cell volume (PCV), albumin (ALB), the activities of ceruloplasmin (CP), Cu/Znsuperoxide dismutase (Cu/Zn-SOD) and catalase (CAT) in group I were significantly lower than those in C group, group II, III, IV (P<0.05), but malondialdehyde (MDA) concentration was higher. The activities of these antioxidant enzymes and MDA concentration had no significant difference between C group, group II, III, IV (P>0.05), but group III had the highest antioxidant enzymes activity and the lowest MDA concentration. There was no significant difference in manganese (Mn), zinc (Zn), iron (Fe), molybdenum (Mo), selenium (Se), red blood cell count (RBC), white blood cell count (WBC), blood urea nitrogen (BUN), alanine transaminase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (GOT), total cholesterol (TC), manganese-superoxide dismutase (Mn-SOD) between all groups (P>0.05). Conclusion: The function of antioxidant system of the native sheep in Weining County have seriously reduced. Added CuSO 4 to the diet increase the activity of antioxidant enzymes and improve the health parameters, but them did not increase linearly. Added 40 mg/kg CuSO 4 , the activity of antioxidant enzymes was the highest and the content of MDA was the lowest. Therefore, it is recommended to add 40 mg/kg CuSO 4 to diet of the native sheep in Weining County.

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“…Throughout the entire duration of the experiment, there were no visual changes to the health state of the horses. The blood of the horses was analysed by a Randox RX Monza biochemical analyser (Randox Laboratories, Crumlin, United Kingdom) using commercial DiaSys kits (Diagnostic Systems GmbH, Holzheim, Germany) (Massanyi et al 2014;Halo et al 2017;Kovacik et al 2017;Kovacik et al 2019). E3), but the differences were not significant (Table 2, Figures 1-6).…”

Section: Resultsmentioning

confidence: 99%

The effect of induced training on selected equine blood plasma indicators on treadmill trained horses

Kováčik¹,

Halo²,

Imrich³

et al. 2020

Vet. Med.

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The aim of this study was to evaluate the effect of induced training on the horses’ metabolism during an experiment lasting nine weeks where we continually scaled up the load on the horses by three defined stages. Blood was obtained from eighteen horses – two stallions, eight mares and eight geldings. In the experiment, we focused on the biochemical analysis of the blood plasma on multiple mineral profile indicators – Ca, P, Mg, K, Cl and Na, and some other variables (energy, nitrogen, AST, ALT, glucose, urea, creatinine kinase, total proteins). The result showed significant changes between the groups in most indicators. A significant increase in the potassium, phosphorus and calcium and a decrease in the concentrations of magnesium over the course of the experiment were found. For the other indicators, a significant increase in the activities of the AST and ALT out of the other indicators and the fluctuating values in the total proteins were noticed. Summarised, significant changes of multiple indicators were observed in different stages of the experiment. These changes had no visible effect on the horses’ organisms throughout entire duration of the experiment and were most probably caused by the muscular work and possible muscular damage during training.

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Seasonal variations in the blood concentration of selected heavy metals in sheep and their effects on the biochemical and hematological parameters

Cited by 44 publications

References 48 publications

Changes of macromineral and trace element concentration in the blood of ewes during lactation period

Changes of macromineral and trace element concentration in the blood of ewes during lactation period

Effect of Different Copper Levels in Feed on Antioxidant Capacity in Stocking the Native Sheep in the Wumeng Prairie

The effect of induced training on selected equine blood plasma indicators on treadmill trained horses

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Seasonal variations in the blood concentration of selected heavy metals in sheep and their effects on the biochemical and hematological parameters

Cited by 44 publications

References 48 publications

Changes of macromineral and trace element concentration in the blood of ewes during lactation period

Changes of macromineral and trace element concentration in the blood of ewes during lactation period

Effect of Different Copper Levels in Feed on Antioxidant Capacity in Stocking the Native Sheep in the Wumeng Prairie

The effect of induced training on selected equine blood plasma indicators on treadmill trained horses

Contact Info

Product

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The effect of induced training on selected equine blood plasma indicators on treadmill trained horses