Seasonal variation of cancer mortality in Hungary between 1984 and 2013

Virág, Katalin; Nyári, Tibor

doi:10.1177/1403494817744074

Cited by 6 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another large clinical study including 959 307 malignant tumor deaths in Hungary between 1984 and 2013 has demonstrated that the mortality was highest in the winter. However, the amplitude was small (winter to summer ratio, 1.034) 6 . In HD patients, no significant seasonal variation has been shown 8 .…”

Section: Discussionmentioning

confidence: 96%

“…Death from malignant tumor has shown little or no seasonal variation 5,6,8 . A large clinical study including over 54 million deaths in 19 countries has shown that cancer mortality presented no substantial seasonality 5 .…”

Section: Discussionmentioning

confidence: 99%

“…Seasonal variations of various diseases in the general population have been investigated in numerous papers [1][2][3][4][5][6] . For example, heart failure, acute myocardial infarction, and sepsis owing to respiratory infection have a peak in the winter, whereas mortality from cancer has little or no seasonal variation.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Seasonal variations in cause-specific mortality and transition to renal replacement therapy among patients with end-stage renal disease

Goto

Hamano

Ogata

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Despite some studies showing seasonal variations in mortality and the transition to renal replacement therapy in patients with end-stage renal disease, detailed evidence is still scarce. We investigated seasonal variations in patients with end-stage renal disease using a large Japanese database for dialysis patients. We compared the fractions of all-cause and cause-specific mortality and the transition to renal replacement therapy among seasons and performed a mixed-effects Poisson regression analysis to compare the mortality among seasons after adjustment for some variables. The initiation of hemodialysis was highest in winter and lowest in summer. Seasonality in the initiation of peritoneal dialysis and transition to kidney transplantation differed from hemodialysis. All-cause mortality was highest in the winter and lowest in the summer. Death from coronary artery disease, heart failure, cerebral hemorrhage, and infectious pneumonia had similar seasonality, but death from cerebral infarction, septicemia, or malignant tumor did not have similar seasonality. In conclusion, the initiation of hemodialysis, all-cause mortality, and mortality from coronary heart disease, heart failure, cerebral hemorrhage, and infectious pneumonia were significantly highest in winter and lowest in summer. However, the initiation of peritoneal dialysis, transition to kidney transplantation, or mortality from cerebral infarction, septicemia, or malignant tumor did not have similar seasonal variations.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Seasonal variations in cause-specific mortality and transition to renal replacement therapy among patients with end-stage renal disease

Goto

Hamano

Ogata

et al. 2020

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Previous studies present the seasonal variation in different types of cancer mortality which might be related to season specific factors such as infections, cold, diet, and environmental pollutants. [ 17 18 19 20 ]…”

Section: Discussionmentioning

confidence: 99%

Diagnostic utility of ultrasound-guided fine-needle aspiration cytology in gall bladder lesions: an experience from a tertiary care cancer center in Eastern India

Rout¹,

Hota

Dash³

et al. 2021

J Cytol

View full text Add to dashboard Cite

Introduction: Gallbladder cancer (GBC) is the most common malignancy, representing 80–95% of biliary tract cancers. Although ultrasonography-guided fine-needle aspiration cytology (USG-FNAC) has emerged as an effective diagnostic the tool for the precise diagnosis of gallbladder lesions, data on its diagnostic utility and cytomorphological categorization of gallbladder lesions are lacking. Aims: To study the diagnostic utility of USG-FNAC in gallbladder lesions. Materials and Methods: This study was the conducted prospectively on patients who came with clinical and radiological evidence of gallbladder space-occupying lesion and then advised to USG-FNAC over 2 years and 6 months from January 2018 to June 2020. Results: A total of 314 cases were included. The mean age was 56 years, with a range of 17–88 years. Women predominated over men (Male:Female = 1:2.3). Primary adenocarcinoma of the gallbladder was most common. On cyto-histological correlation, the sensitivity, specificity, and diagnostic accuracy of USG-FNAC of gallbladder lesions were found to be 98.82, 87.23, and 96.3%, respectively. Conclusion: The USG-FNAC of gallbladder lesion was found to be an easy, quick, cost-effective, and presumptive diagnostic procedure. It should be opted as an initial preoperative diagnostic modality in high incidence areas to avoid inappropriate management with unnecessary morbidity and cost. Moreover, a close cytological examination of the architectural pattern and the cytomorphological features would help in the sub-typing and prognosticating the tumor.

show abstract

“…Cancer remains the chief and ever-expanding culprit in human mortality that prompts significant concerns in every country [ 1 ]. As the International Agency for Research on Cancer (IARC) reported, this intractable disease had been emerging in approximately 18.1 million new cases and thus leading to 9.6 million cancer deaths in 2018 [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers

Zhou

Zou

et al. 2022

IJMS

View full text Add to dashboard Cite

To develop novel microtubule-binding agents for cancer therapy, an array of N-cinnamoyl-N’-(substituted)acryloyl hydrazide derivatives were facilely synthesized through a two-step process. Initially, the antiproliferative activity of these title compounds was explored against A549, 98 PC-3 and HepG2 cancer cell lines. Notably, compound I23 exhibited the best antiproliferative activity against three cancer lines with IC50 values ranging from 3.36 to 5.99 μM and concurrently afforded a lower cytotoxicity towards the NRK-52E cells. Anticancer mechanism investigations suggested that the highly bioactive compound I23 could potentially promote the protofilament assembly of tubulin, thus eventually leading to the stagnation of the G2/M phase cell cycle of HepG2 cells. Moreover, compound I23 also disrupted cancer cell migration and significantly induced HepG2 cells apoptosis in a dosage-dependent manner. Additionally, the in silico analysis indicated that compound I23 exhibited an acceptable pharmacokinetic profile. Overall, these easily prepared N-cinnamoyl-N’-(substituted)acryloyl hydrazide derivatives could serve as potential microtubule-interacting agents, probably as novel microtubule-stabilizers.

show abstract

Seasonal variation of cancer mortality in Hungary between 1984 and 2013

Abstract: This study presents the seasonality pattern of different types of cancer mortality which might be related to environmental factors (e.g. infections).

Cited by 6 publications

References 11 publications

Seasonal variations in cause-specific mortality and transition to renal replacement therapy among patients with end-stage renal disease

Seasonal variations in cause-specific mortality and transition to renal replacement therapy among patients with end-stage renal disease

Diagnostic utility of ultrasound-guided fine-needle aspiration cytology in gall bladder lesions: an experience from a tertiary care cancer center in Eastern India

Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers

Contact Info

Product

Resources

About