Seasonal variation, chemical composition and biological activity of the essential oil of Cordia verbenacea DC (Boraginaceae) and the sabinene

Matias, Edinardo Fágner Ferreira; Alves, Erivania Ferreira; Silva, Maria K.N.; Carvalho, Victoria R.A.; Figueredo, Fernando Gomes; Ferreira, João V.A.; Coutinho, Henrique Douglas Melo; Silva, João M.F.L.; Ribeiro-Filho, Jaime; Costa, José G.M.

doi:10.1016/j.indcrop.2016.04.028

Cited by 73 publications

(38 citation statements)

References 45 publications

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“…Although O. vulgare subsp. vulgare contains small amounts of these active phenolic monoterpenes, this subspecies also indicate such activity, associated in this case with a high content of sabinene [39,40]. However, populations rich in linalool and/or sesquirepenes (i.a.…”

Section: Results and Disscusionmentioning

confidence: 83%

Morphological and chemical variability of common oregano (Origanum vulgare L. subsp. vulgare) occurring in eastern Poland

Kosakowska

Czupa

2018

Herba Polonica

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SummaryIntroduction: Common oregano is an important medicinal and aromatic plant, characterized by a high morphological and chemical variability.Objective: The aim of the work was to determine the diversity of 14 common oregano populations introduced intoex situconditions, in respect of morphological and developmental traits as well as content and composition of essential oil in herb.Methods: Observations and harvest of raw material were performed in the second year of plant vegetation. Morphological and developmental characters were estimated. Total content of essential oil was determined according to European Pharmacopoeia 8th. The composition of essential oil was carried out by gas chromatography.Results: Populations differed in respect of examined traits, i.a.: plant's height from 52.13 to 88.66 cm, number of stems per plant from 45.6 to 123.3, number of internodes per stem from 4.6 to 9.2. Fresh mass of herb was at a level of 249.0–896.6 g per plant. Total content of essential oil ranged from 0.35 to 0.87%. Sabinene, 1,8-cineole, linalool,p-cymene,β-caryophyllene and caryophyllene oxide were the dominant compounds in essential oil.Conclusions: Number of stems and fresh mass of herb differentiated examined populations at the highest degree. Most of populations were classified as a sabinyl chemotype rich in sesquiterpenes.

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Section: Results and Disscusionmentioning

confidence: 83%

Morphological and chemical variability of common oregano (Origanum vulgare L. subsp. vulgare) occurring in eastern Poland

Kosakowska

Czupa

2018

Herba Polonica

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“…With respect to previous reports, 1,[7][8][9][10][11] yields are comparable, but little difference may be related with seasonal variation or growing habitats. 19,20 The results obtained from the GC-MS analysis are presented in Table 1, on the basis of their elution order on the HP-5 column. A total of 50 components were identified.…”

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confidence: 99%

Essential Oil From Psidium guajava Leaves: An Excellent Source of β-Caryophyllene

Arain

Sherazi

Mahesar

et al. 2019

Natural Product Communications

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The purpose of this study was to investigate the chemical composition of the essential oil extracted from Psidium guajava leaves and to explore the medicinal value of β-caryophyllene in pharmaceutical science. The essential oils of P. guajava leaves were extracted by the hydrodistillation method, using a Clevenger-type apparatus and the chemical composition of essential oils was investigated by gas chromatography-mass spectrometry. The yield of extracted essential oils was 0.6% (w/w) dry weight. The main compounds found in the leaves were β-caryophyllene (20.34%), globulol (8.20%), trans-nerolidol (7.72%), aromadendrene (4.34%), cis-α-bisabolene (3.82%), tetracosane (3.68%), octadecane (3.66%), Z,Z,Z-1,5,9,9-tetramethyl-1,4,7cycloundecatriene (3.44%), β-bisabolene (3.41%), limonene (3.09%), octacosane (2.88%), δ-cadinene (2.52%), and 1,4-cadadiene (2.04%). The main chemical class of the essential oil was terpenoids, which represent 71.65%, followed by hydrocarbons (26.31%). A total of 50 components were identified, among these β-caryophyllene was found to be dominant, which has great medicinal value, and some other compounds were also identified for the first time in the essential oil of P. guajava leaves.

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“…[15][16] Another important component that had antimicrobial activity could be sabinene, as has been reported previously. 17 The present study showed that ME and EAE can be further exploited as natural antibacterial agents.…”

Section: Antibacterial Activitymentioning

confidence: 53%

Bioactivities of Methanol and Ethyl Acetate Mace Extracts of Myristica fragrans Houtt

Simamora¹,

Santoso²,

Timotius³

2018

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Introduction: Myristica fragrans Houtt is used as a spice in Indonesia. This study aimed to scientifically validate the traditional use of mace from M. fragrans. Methods: The mace was extracted with methanol and ethyl acetate, and the chemical composition was analysed by GC-MS. The extracts were evaluated for their antibacterial activities against seven different bacteria based on a well diffusion method, their antioxidant activities based on DPPH radical scavenging assay, and their α-glucosidase inhibitory activities in vitro. Results: Four major components were identified from both extracts: sabinene, methoxyeugenol, myristicin, and elemicin. The methanol extract (ME) had higher methoxyeugenol, myristicin and elimisin levels, whereas sabinene was dominant in ethyl acetate extract (EAE). Both extracts showed good antibacterial activity against S. aureus only. Both extracts showed good antioxidant activities, in which EAE showed stronger activity than ME (IC 50 94 μg GAE/ml and IC 50 162 μg GAE/ml, respectively). Further more, both extracts inhibited α-glucosidase more strongly than the standard acarbose, in which ME (IC 50 7.50 μg GAE/ml) exhibited stronger α-glucosidase inhibitory capacity than EAE (IC 50 10.65 μg GAE/ml). Conclusion:The results suggest that ME and EAE of M. fragrans have biological activities with high potential for pharmacological uses.

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Seasonal variation, chemical composition and biological activity of the essential oil of Cordia verbenacea DC (Boraginaceae) and the sabinene

Cited by 73 publications

References 45 publications

Morphological and chemical variability of common oregano (Origanum vulgare L. subsp. vulgare) occurring in eastern Poland

Morphological and chemical variability of common oregano (Origanum vulgare L. subsp. vulgare) occurring in eastern Poland

Essential Oil From Psidium guajava Leaves: An Excellent Source of β-Caryophyllene

Bioactivities of Methanol and Ethyl Acetate Mace Extracts of Myristica fragrans Houtt

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