Seasonal trends of diagnosis of childhood malignant diseases and viral prevalence in South Korea

Abstract

This study tentatively suggests that the diagnosis of childhood malignancy follows a seasonal trend in Korea, and has a possible correlation with viral prevalence in several diseases. Further long-term analysis of epidemiological data is needed to explore possible causality.

Birth seasonality of childhood central nervous system tumors: Analysis of primary data from 16 Southern‐Eastern European population‐based registries

“…The potential association of season of birth with the risk of childhood cancers has been previously investigated in an attempt to shed light in the complex etiology of childhood carcinogenesis . Certain researchers have suggested a seasonal variation in several types of cancer, such as leukemia, non‐Hodgkin lymphoma, neuroblastoma and CNS tumors, whereas other studies have not confirmed similar associations .…”

“…The potential association of season of birth with the risk of childhood cancers has been previously investigated in an attempt to shed light in the complex etiology of childhood carcinogenesis. [29][30][31] Certain researchers have suggested a seasonal variation in several types of cancer, such as leukemia, non-Hodgkin lymphoma, neuroblastoma and CNS tumors, 21,29,31 whereas other studies have not confirmed similar associations. 30 Consistently with our findings, a recent systematic review of the literature (n = 7 studies) 22 showed a potential peak of births in autumn and winter months among children and adults diagnosed with CNS tumors; however, the results were based on studies suffering lack of power, not reporting the size of effect, neither were the findings confined to specific histological subtypes.…”

Ecological Factors Associated With Fluctuations in the Incidence of Neoplasms in Children

“…Применительно к роли ЭФ в возникновении ЗН у детей в настоящее время известно, что 5-10 % данной патологии связаны с ионизирующей радиацией [22]. Есть данные о корреляции частоты острого лимфобластного лейкоза, нейробластомы и лимфогранулематоза с сезонными колебаниями распространенности вирусных инфекций [26]. Сол-нечное ультрафиолетовое излучение снижает риск развития острого лимфобластного лейкоза, гепатобластомы и неходжкинской лимфомы [21], однако увеличивает риск возникновения ретинобластомы [18].…”

The contribution of meta-analytical methodology to the investigation of primary central nervous system tumors

“…The association of season of birth with the diagnosis of pediatric cancer has been previously investigated [276,411,412] in an attempt to shed light in the complex etiology of childhood carcinogenesis. Certain researchers have suggested a seasonal variation for some types of cancer, such as leukemia, non-Hodgkin lymphoma, neuroblastoma and CNS tumors [276,288,412], whereas other studies have not confirmed similar associations [411].…”

“…The association of season of birth with the diagnosis of pediatric cancer has been previously investigated [276,411,412] in an attempt to shed light in the complex etiology of childhood carcinogenesis. Certain researchers have suggested a seasonal variation for some types of cancer, such as leukemia, non-Hodgkin lymphoma, neuroblastoma and CNS tumors [276,288,412], whereas other studies have not confirmed similar associations [411]. Consistently with our findings, a recent systematic review of the literature (N=7 studies) [291] showed a potential peak of births among children and adults with CNS tumors in fall and winter months; however, the results were in general based on studies suffering lack of power, which did not report the size of effect, neither were the findings confined to specific histological subtypes.…”