Seasonal prevalence of Cryptococcus neoformans var. grubii and Cryptococcus gattii inhabiting Eucalyptus terreticornis and Eucalyptus camaldulensis trees in Jabalpur City of Madhya Pradesh, Central India

Bedi, Namita; Nawange, S.R.; Singh, S. M.; Naidu, J.; Kavishwar, Arvind

doi:10.1016/j.mycmed.2012.09.001

Cited by 12 publications

(11 citation statements)

References 19 publications

(29 reference statements)

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“…However, clinical cases of C. deneoformans were documented in the Black Sea coastal area (Kaya et al, 2012;Birinci et al, 2016), which is distant from the Aegean coast and where the climate is more humid and the temperature lower. This finding is consistent with reports that C. deneoformans is more sensitive to heat than C. neoformans (Martinez et al, 2001;Lin and Heitman, 2006;Bedi et al, 2012). The discrepancy between the environmental presence of C.…”

Section: Discussionsupporting

confidence: 91%

“…Warmer temperatures can affect Cryptococcus spp. spread, especially that of C. gattii, a sibling species of C. neoformans (Granados and Castañeda, 2006;Randhawa et al, 2011;Bedi et al, 2012;Chowdhary et al, 2012, Uejio et al, 2015Cogliati et al, 2016b).…”

Section: Discussionmentioning

confidence: 99%

“…In addition, it has been isolated from various tree species (Ellis and Pfeiffer, 1990;Randhawa et al, 2008Randhawa et al, , 2011Cogliati et al, 2016a, b). Following the first report of C. neoformans isolation from trees in Australia (Ellis and Pfeiffer, 1990), many studies have confirmed the environmental association of Cryptococcus with plants in different climatic zones (Granados andCastañeda, 2005, 2006;Randhawa et al, 2008Randhawa et al, , 2011Bedi et al, 2012;Chowdhary et al, 2012). Several studies have characterized the properties of these yeasts that contribute to the colonization of new environmental niches (Granados and Castañeda, 2006;Randhawa et al, 2008;Ergin and Kaleli, 2010;Ergin et al, 2014;Sengul et al, 2019).…”

Section: Introductionmentioning

confidence: 97%

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Cryptococcus neoformansrecovered from olive trees (Olea europaea) in Turkey reveal allopatry with African and South American lineages

Ergin

Şengül

Aksoy

et al. 2019

Preprint

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Cryptococcus species are life-threatening human fungal pathogens that cause cryptococcal meningoencephalitis in both immunocompromised and healthy hosts. The natural environmental niches of Cryptococcus include pigeon (Columba livia) guano, soil, and a variety of tree species such as Eucalyptus camaldulensis, Ceratonia siliqua, Platanus orientalis, and Pinus spp. Genetic and genomic studies of extensive sample collections have provided insights into the population distribution and composition of different Cryptococcus species in geographic regions around the world. However, few such studies examined Cryptococcus in Turkey. We sampled 388 Olea europaea (olive) and 132 E. camaldulensis trees from 7 locations in coastal and inland areas of the Aegean region of Anatolian Turkey in September 2016 to investigate the distribution and genetic diversity present in the natural Cryptococcus population. We isolated 84 Cryptococcus neoformans strains (83 MATα and 1 MATa) and 3 Cryptococcus deneoformans strains (all MATα) from 87 (22.4% of surveyed) O. europaea trees; a total of 32 C. neoformans strains were isolated from 32 (24.2%) of the E. camaldulensis trees, all of which were MATα. A statistically significant difference was observed in the frequency of C. neoformans isolation between coastal and inland areas (P < 0.05). Thus, O. europaea trees could represent a novel niche for C. neoformans. Interestingly,the MATa C. neoformans isolate was fertile in laboratory crosses with VNI and VNB MATα tester strains and produced robust hyphae, basidia, and basidiospores, thus suggesting potential sexual reproduction in the natural population. Sequencing analyses of the URA5 gene identified at least 5 different genotypes among the isolates. Population genetics and genomic analyses revealed that most of the isolates in Turkey belong to the VNBII lineage of C. neoformans, which is predominantly found in southern Africa; these isolates are part of a distinct minor clade within VNBII that includes several isolates from Zambia and Brazil. Our study provides insights into the geographic distribution of different C. neoformans lineages in the Mediterranean region and highlights the need for wider geographic sampling to gain a better understanding of the natural habitats, migration, epidemiology, and evolution of this important human fungal pathogen.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

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Cryptococcus neoformansrecovered from olive trees (Olea europaea) in Turkey reveal allopatry with African and South American lineages

Ergin

Şengül

Aksoy

et al. 2019

Preprint

View full text Add to dashboard Cite

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“…Recently, C. grubii was isolated from the bark of Eucalyptus trees followed by flower, bud, fruit, and detritus [ 19 ]. The prevalence of C. grubii in this study (4.2%) is somewhat near to the rate of Nawange et al's (2006) [ 18 ] study (5.5%), while the recovery rate of C. grubii is the highest from flowers (7.9%), then leaves (3.6%), and finally woody trunks (1.1%) ( Table 3 ).…”

Section: Discussionmentioning

confidence: 99%

EucalyptusTree: A Potential Source ofCryptococcus neoformansin Egyptian Environment

Elhariri

Hamza

Elhelw

et al. 2016

International Journal of Microbiology

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In Egypt, the River Red Gum (Eucalyptus camaldulensis) is a well-known tree and is highly appreciated by the rural and urban dwellers. The role of Eucalyptus trees in the ecology of Cryptococcus neoformans is documented worldwide. The aim of this survey was to show the prevalence of C. neoformans during the flowering season of E. camaldulensis at the Delta region in Egypt. Three hundred and eleven samples out of two hundred Eucalyptus trees, including leaves, flowers, and woody trunks, were collected from four governorates in the Delta region. Thirteen isolates of C. neoformans were recovered from Eucalyptus tree samples (4.2%). Molecular identification of C. neoformans was done by capsular gene specific primer CAP64 and serotype identification was done depending on LAC1 gene. This study represents an update on the ecology of C. neoformans associated with Eucalyptus tree in Egyptian environment.

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“…[1][2][3][4][5][6][7][8] Infection occurs through inhalation of spores or desiccated yeasts and has been documented in both humans and animals. [1][2][3][4][5][6][7][8] Infection occurs through inhalation of spores or desiccated yeasts and has been documented in both humans and animals.…”

mentioning

confidence: 99%

A Case of Cryptococcus gattii in Western Florida

Tiro¹,

Springer²,

Irby³

et al. 2015

Infectious Diseases in Clinical Practice

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Background: Cryptococcus gattii is an environmental pathogenic yeast that produces disease in the skin, the respiratory tract, and the central nervous system of both immunocompromised and immunocompetent hosts. The incidence of C. gattii disease is increasing in frequency and, importantly, appears to be spreading its geographic clinical appearance since the first identified case series, which had shown defined boundaries.Case: A 56-year-old previously healthy woman presented for medical care with 3 weeks of progressive weakness, headache, neck pain, and back pain. Initial computed tomographic scan results of the head and the spine were normal. However, chest x-ray showed a large right upper lobe mass. Bronchoscopic examination revealed a partially obstructing endobronchial polyp, on which a biopsy was performed, and culture of the tissue grew encapsulated yeast cells. Magnetic resonance imaging of the brain revealed multiple rim-enhancing lesions, and cerebrospinal fluid grew encapsulated yeasts that were identified as C. gattii, molecular-type VGI.Conclusions: This is a virulent VGI strain of C. gattii, causing infection in an immunocompetent host in Western Florida with no recent travel history. Here, we discuss clinical, laboratory, diagnostic, and pathologic findings of the clinical presentation and its delayed diagnostic appearance in a nonendemic area.

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Seasonal prevalence of Cryptococcus neoformans var. grubii and Cryptococcus gattii inhabiting Eucalyptus terreticornis and Eucalyptus camaldulensis trees in Jabalpur City of Madhya Pradesh, Central India

Cited by 12 publications

References 19 publications

Cryptococcus neoformansrecovered from olive trees (Olea europaea) in Turkey reveal allopatry with African and South American lineages

Cryptococcus neoformansrecovered from olive trees (Olea europaea) in Turkey reveal allopatry with African and South American lineages

EucalyptusTree: A Potential Source ofCryptococcus neoformansin Egyptian Environment

A Case of Cryptococcus gattii in Western Florida

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