Seasonal pattern of manic episode admissions among bipolar I disorder patients is associated with male gender and presence of psychotic features

Hochman, Eldar; Valevski, Avi; Onn, Roy; Weizman, Abraham; Krivoy, Amir

doi:10.1016/j.jad.2015.10.002

Cited by 24 publications

(21 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Third, analyzing the monthly distribution of admissions, we observed a significant increase of involuntary hospitalizations during changes of season in particular in spring/summer with a peak in June. In spring/summer, high hospitalization rates for manic episode (as principal reason for involuntary admission) are well stated, due to an increase in total sunshine hours and length of the average monthly days (Wang & Chen 2013;Abreu & Braganca 2015;Hochman et al 2016). Other studies showed, in addition to the main peak in spring/summer, a lower frequency of manic involuntary admissions in autumn (Cassidy & Carroll 2002;Lee et al 2002;Morken et al 2002;Volpe and Del Porto 2006;Lee et al 2007;Volpe et al 2010;Yang et al 2013;Geoffroy et al 2014).…”

Section: Discussionmentioning

confidence: 96%

“…Irregular chronobiology in terms of disrupted sleep and dysregulation of circadian rhythms with a greater seasonal fluctuations in mood and behaviour is a characteristic pattern of bipolar patients compared to unipolar depression patients or healthy controls (Geoffroy et al 2014). Patients suffering from manic episode have higher rates of admission during spring and summer (Lee et al 2007;Volpe et al 2010;Amr & Volpe 2012;Wang & Chen 2013;Hochman et al 2016). Furthermore, the prevalence of hospitalization in patients with bipolar depression has a main peak in early winter and a minor one in summer (Modai et al 1994;Avasthi et al 2001;Lee et al 2007;Amr & Volpe 2012;Yang et al 2013;Dominiak et al 2015).…”

Section: Objectivementioning

confidence: 99%

See 1 more Smart Citation

Involuntary admissions in Italy: the impact of seasonality

Aguglia

Moncalvo

Solia

et al. 2016

International Journal of Psychiatry in Clinical Practice

View full text Add to dashboard Cite

Objective: The aim of this study is to assess the prevalence of involuntary admissions with regard to seasonality and clinical associated features, in a sample of patients admitted to a psychiatric unit in a period of 24 months. Methods: All subjects consecutively admitted to the Psychiatric Inpatient Unit of the San Luigi Gonzaga Hospital, Orbassano (University of Turin, Italy) from September 2013 to August 2015 were recruited. Socio-demographic and clinical characteristics were collected. Results: Seven hundred and thirty admissions in psychiatric ward were recognized. The prevalence of involuntary admission was 15.4%. Patients with involuntary hospitalizations showed a higher education level, a higher prevalence of admission in spring/summer with a significant peak in June, a longer duration of hospitalization and a lower suicide ideation. Among involuntary admissions, physical restraint and suicide attempts were more prevalent during spring compared to the other seasons. Conclusions: Seasonality has an important role in the psychopathology of psychiatric disorders, particularly in bipolar and related disorder, and may represent an influencing factor in hospital admissions and hospitalizations. Seasonal pattern must be considered while managing diagnosis and treatment of mental disorders, with regard to prevention and psychoeducation of patients.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Objectivementioning

confidence: 99%

Involuntary admissions in Italy: the impact of seasonality

Aguglia

Moncalvo

Solia

et al. 2016

International Journal of Psychiatry in Clinical Practice

View full text Add to dashboard Cite

show abstract

“…10 All of these results are important for the prognosis of BD. 14, 15 Hochman et al suggested that bipolar patients with seasonal patterns have a more severe form of the disorder due to the association of psychotic features. 15 These results in our study being significantly different in the group with seasonal patterns seems to be the factor adversely affecting the prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…3 These results show us that bipolar patients with seasonal patterns have poorer prognoses than bipolar patients without seasonal patterns. [14][15][16][17][18][19] However, seasonality is not among the prognostic indicators of BD.…”

Section: Discussionmentioning

confidence: 99%

“…11 In one study, seasonal patterns were found in equal numbers for both manic episodes and depressive episodes, while another study showed seasonality frequently occurs in manic episodes in males and depressive episodes in females; in other words, seasonality was impressed by gender. 4,15,20 Furthermore, Kim et al suggested that in BD II, seasonal patterns were associated with female gender. 10 In our study, gender was not determined to be statistically significant with or without seasonal patterns in BD.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of sociodemographic and clinical characteristics of bipolar patients with and without seasonal patterns

Berkol¹,

Kırlıoğlu²,

Balcıoğlu³

et al. 2017

Anadolu Psikiyatri Derg

View full text Add to dashboard Cite

show abstract

Cingulate abnormalities in bipolar disorder relate to gender and outcome: a voxel-based morphometry study

Delvecchio

Ciappolino

Perlini

et al. 2018

Eur Arch Psychiatry Clin Neurosci

View full text Add to dashboard Cite

Structural magnetic resonance imaging (MRI) studies reported gray matter (GM) loss in bipolar disorder (BD) in cingulate cortices, key regions subserving emotional regulation and cognitive functions in humans. The aim of this study was to further explore cingulate GM volumes in a sizeable group of BD patients with respect to healthy controls, particularly investigating the impact of gender and clinical variables. 39 BD patients (mean Age = 48.6 ± 9.7, 15 males and 24 females) and 39 demographically matched healthy subjects (mean Age = 47.9 ± 9.1, 15 males and 24 females) underwent a 1.5T MRI scan. GM volumes within the cingulate cortex were manually detected, including anterior and posterior regions. BD patients had decreased left anterior cingulate volumes compared with healthy controls (F = 6.7, p = 0.01). Additionally, a significant gender effect was observed, with male patients showing reduced left anterior cingulate cortex (ACC) volumes compared to healthy controls (F = 5.1, p = 0.03). Furthermore, a significant inverse correlation between right ACC volumes and number of hospitalizations were found in the whole group of BD patients (r = - 0.51, p = 0.04) and in male BD patients (r = - 0.88, p = 0.04). Finally, no statistically significant correlations were observed in female BD patients. Our findings further confirm the putative role of the ACC in the pathophysiology of BD. Interestingly, this study also suggested the presence of gender-specific GM volume reductions in ACC in BD, which may also be associated to poor outcome.

show abstract

Seasonal pattern of manic episode admissions among bipolar I disorder patients is associated with male gender and presence of psychotic features

Cited by 24 publications

References 26 publications

Involuntary admissions in Italy: the impact of seasonality

Involuntary admissions in Italy: the impact of seasonality

Comparison of sociodemographic and clinical characteristics of bipolar patients with and without seasonal patterns

Cingulate abnormalities in bipolar disorder relate to gender and outcome: a voxel-based morphometry study

Contact Info

Product

Resources

About