Seasonal effects on attempts to synchronize estrus and ovulation by intravaginal application of progesterone-releasing device (PRID™) in mares

Handler, Johannes; Schönlieb, Sabine; Hoppen, H. O.; Aurich, Christine

doi:10.1016/j.theriogenology.2005.07.013

Cited by 17 publications

(32 citation statements)

References 25 publications

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“…Hormonal protocols based on the single use of a P4 intravaginal device have been used for the induction and advancement of the breeding season (Hanlon and Firth 2012). Although some authors have reported satisfactory outcomes in OR (Arbeiter et al 1994 or induction of cyclicity in anestrous mares with the one-time use of an intravaginal device, other studies do not corroborate these findings (Alexander and Irvine 1991, Handler et al 2006, Handler et al 2007). Our hypothesis was that the double insertion of intravaginal P4 could optimize ovarian cyclicity in anestrous mares, even under non-ideal BCS conditions.…”

Section: Discussionmentioning

confidence: 99%

“…Another study in anestrous mares showed similar outcomes (OR was 60,0 %) at 5.3 days post treatment, but there was no difference in pregnancy rate (PR) between cyclic animals and those in anestrus (Newcombe et al 2002). There were also no differences between OR and PR among cyclic and anestrous mares (Arbeiter et al 1994, Handler et al 2006. However, the results of using P4 in anestrous mares are inconsistent.…”

Section: Introductionmentioning

confidence: 89%

“…The anestrus phase is characterized by a relatively relaxed cervix, lack of uterine tonus or endometrial edema, ovaries with follicles < 25 mm, and no corpus luteum (CL) (Newcombe 1994, Newcombe 2002, Handler et al, 2007. Mares carrying follicles smaller than 10 mm are characterized as being in the deep anestrus phase (Handler et al 2006). The ultrasonographic characteristics of the uterus (endometrial edema) and follicles (diameter > 35.0 mm) help to identify the optimal period for female reproduction (Hayes et al 1985).…”

Section: Introductionmentioning

confidence: 99%

“…The hormone synchronizes estrus, stimulates ovarian activities, and results in favorable outcomes at any time of the year, except in the anestrus period (Handler et al 2006).…”

Section: Introductionmentioning

confidence: 99%

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Two administrations of an intravaginal progesterone device on the induction of ovarian cyclicity in anestrous mares

Polo¹,

Weiss²,

Bertol³

et al. 2016

PHK

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Summary:The study aimed to evaluate the effect of double administration of a progesterone (P4) intravaginal device on induction of ovarian cyclicity in mares. Twelve crossbred mares were assigned to one of two groups. The first group (GP4; n = 6; 100 % in anestrus phase) underwent the following protocol: day (d) 0, 1.9 g of P4 + ultrasound of the uterus and ovaries (US); d 7, US; d10, first P 4 removal + US; d10 -d 24, US daily; d 28, second P4; d 35, US; d 40, second P4 removal + US; d 40 -d 54, US daily; and d 54 -d 76, US every other day. The second group (GNP4; n = 5; 100 % in transition phase) underwent the same protocol as GP4, but without the administration of the P4 device. From d 55 -d 76, 100.0 % of the mares in both groups held uterine tonus and 83.3 % had endometrial edema; after the first and second P4 removal, 66.7 % and 83.3 % of GP4 mares, respectively, reached the transition phase. By d 76, 50.0 % and 80.0 % of the GP4 and GNP4 animals, respectively, had ovulated; the average size of the largest follicle increased from d 0 -d 76 in both groups, but was significant only in GP4. Four to five days after the first and second P4 removals in GP4, follicles showed an average growth of 9.0 mm. At the end of the study, both groups had follicular medium diameters greater than 34 mm (P > 0.05). Ovulations correlated with body condition scores (P < 0.05). In conclusion, two administration of P4 affected ovarian cyclicity in anestrous mares, and synchronized follicular waves and ovulation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%

“…The hormone synchronizes estrus, stimulates ovarian activities, and results in favorable outcomes at any time of the year, except in the anestrus period (Handler et al 2006).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Two administrations of an intravaginal progesterone device on the induction of ovarian cyclicity in anestrous mares

Polo¹,

Weiss²,

Bertol³

et al. 2016

PHK

View full text Add to dashboard Cite

show abstract

“…For these latter, plasma progesterone concentrations seem to follow a similar pattern in ovariectomised cows (Munro 1987) and the capacity of progesterone release from the intra-vaginal device appears to be the main factor limiting vaginal uptake of progesterone (Uehlinger et al 1995). In the mare, Handler et al (2006) investigated the effects of reproductive status and plasma progesterone concentrations of mares at PRID ® (progesterone-alone device) insertion on the progesterone plasma concentration: in cyclic mares, the plasma progesterone concentrations at insertion of PRID ® seemed to be more important for the efficacy of the treatment than the assignment to oestrous cycle stages.…”

Section: Discussionmentioning

confidence: 99%

Pharmacokinetic analysis during intravaginal progesterone-releasing devices (PRID®/CIDR®) application in the mare

Pohl¹,

Buff²,

Garnier³

et al. 2009

PHK

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Update on the management of anoestrus and transitional phase in horses

Crabtree¹

2021

In Practice

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Background: Practitioners are regularly presented with mares in anoestrus or the transitional phase of the reproductive cycle. The first aim for the practitioner is to determine what stage of the cycle the mare is likely in and then determine the likely timescale to spontaneous cyclic activity. If it is desirable for the mare to be bred sooner than this, management and/or pharmacological strategies can be implemented in an attempt to advance cyclic activity.Aim of the article: This article aims to update the practitioner with regard to the current and future methods of management and pharmacological therapies available to stimulate cyclic activity in the mare in anoestrus or transitional phase of the reproductive cycle.

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Seasonal effects on attempts to synchronize estrus and ovulation by intravaginal application of progesterone-releasing device (PRID™) in mares

Cited by 17 publications

References 25 publications

Two administrations of an intravaginal progesterone device on the induction of ovarian cyclicity in anestrous mares

Two administrations of an intravaginal progesterone device on the induction of ovarian cyclicity in anestrous mares

Pharmacokinetic analysis during intravaginal progesterone-releasing devices (PRID®/CIDR®) application in the mare

Update on the management of anoestrus and transitional phase in horses

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