Search strategies to identify observational studies in MEDLINE and EMBASE

Belisario, José S Marcano; Car, Lorainne Tudor; Reeves, Tim; Gunn, Laura H; Car, Josip

doi:10.1002/14651858.mr000041

Cited by 9 publications

(3 citation statements)

References 19 publications

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“…Searches were conducted by experienced systematic reviewers (AB and JD) based on established design filters. 26 27 The search strategy combined terms relating to study design (eg, cohort, epidemiological study) and population (eg, knee replacement, knee arthroplasty). Full search strategies are provided in online supplementary appendix 2 .…”

Section: Methodsmentioning

confidence: 99%

Post-operative patient-related risk factors for chronic pain after total knee replacement: a systematic review

Wylde¹,

Beswick²,

Dennis³

et al. 2017

BMJ Open

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ObjectiveTo identify postoperative patient-related risk factors for chronic pain after total knee replacement (TKR).DesignThe systematic review protocol was registered on the International Prospective Register of Systematic Reviews (CRD42016041374). MEDLINE, Embase and PsycINFO were searched from inception to October 2016 with no language restrictions. Key articles were also tracked in the Institute for Scientific Information (ISI) Web of Science. Cohort studies evaluating the association between patient-related factors in the first 3 months postoperatively and pain at 6 months or longer after primary TKR surgery were included. Screening, data extraction and assessment of methodological quality were undertaken by two reviewers. The primary outcome was pain severity in the replaced knee measured with a patient-reported outcome measure at 6 months or longer after TKR. Secondary outcomes included adverse events and other aspects of pain recommended by the core outcome set for chronic pain after TKR.ResultsAfter removal of duplicates, 16 430 articles were screened, of which 805 were considered potentially relevant. After detailed evaluation of full-text articles, 14 studies with data from 1168 participants were included. Postoperative patient-related factors included acute pain (eight studies), function (five studies) and psychosocial factors (four studies). The included studies had diverse methods for assessment of potential risk factors and outcomes, and therefore narrative synthesis was conducted. For all postoperative factors, there was insufficient evidence to draw firm conclusions about the association with chronic pain after TKR. Selection bias was a potential risk for all studies, as none were reported to be conducted at multiple centres.ConclusionThis systematic review found insufficient evidence to draw firm conclusions about the association between any postoperative patient-related factors and chronic pain after TKR. Further high-quality research is required to provide a robust evidence base on postoperative risk factors, and inform the development and evaluation of targeted interventions to optimise patients’ outcomes after TKR.

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Section: Methodsmentioning

confidence: 99%

Post-operative patient-related risk factors for chronic pain after total knee replacement: a systematic review

Wylde¹,

Beswick²,

Dennis³

et al. 2017

BMJ Open

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“…Some of the studies included here generated many different publications some of which may have not been captured by our search strategy and we may have also missed studies altogether. Systematic searches of observational studies are more complex than those limited to RCTs for several reasons including lack of appropriate indexing in the references databases, absence of specialised registries of trials and ambiguity in their definitions . Further limitations are possible due simply to the information provided in the publications reviewed.…”

Section: Discussionmentioning

confidence: 99%

Large variation in measures used to assess outcomes of opioid dependence treatment: A systematic review of longitudinal observational studies

Wiessing

Ferri

Darke

et al. 2017

Drug and Alcohol Review

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Wide variation exists in outcome measures found in longitudinal observational studies of treatment of opioid users. This reduces replicability of studies and suggests a lack of common expectations on treatment success. Future studies should consider using all or most of eight outcome domains identified (excluding economic analyses if unfeasible), non-binary measures and amount/value of drugs used and consensus meetings with joint ownership of scientific, treatment and patient communities.

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“…Using the search strategy recommended by Cochrane [ 29 ], the search terms were chosen to obtain highly sensitive results: the keywords “electromagnetic field,” "child,” “adolescent,” and “epidemiologic studies” were combined with the Medical Subject Headings and Emtree terms S1 Table . We searched in the international databases of MEDLINE (1946 to January Week 3 2020), EMBASE (1988 to January Week 3 2020), and Web of Science (1995 to January Week 4 2020).…”

Section: Methodsmentioning

confidence: 99%

Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis

2021

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Background Extremely low frequency magnetic fields (ELF-MFs) are classified as a possible carcinogenic factor (Group 2B). This study assessed the association between ELF-MFs and childhood cancer through a systematic review and meta-analysis. Methods Three databases were searched in January 2020. We conducted a meta-analysis for the association between the ELF-MFs exposure level and childhood cancer. Results A total of 33 studies were identified. Thirty studies with 186,223 participants were included in the meta-analysis. Children exposed to 0.2-, 0.3-, and 0.4-μT ELF-MFs had a 1.26 (95% confidence interval [CI] 1.06–1.49), 1.22 (95% CI 0.93–1.61), and 1.72 (95% CI 1.25–2.35) times higher odds of childhood leukemia. In childhood brain tumors, children exposed to 0.2-μT had a 0.95 (95% CI 0.59–1.56) times higher odds, and those exposed to 0.4-μT ELF-MFs had a 1.25 (95% CI 0.93–1.61). Children exposed to 0.2- and 0.4-μT ELF-MFs had a 1.10 (95% CI 0.70–1.75) and 2.01 (95% CI 0.89–4.52) times higher odds of any childhood cancers. Conclusions Significant associations were observed between exposure to ELF-MFs and childhood leukemia. Furthermore, a possible dose-response effect was also observed.

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Search strategies to identify observational studies in MEDLINE and EMBASE

Cited by 9 publications

References 19 publications

Post-operative patient-related risk factors for chronic pain after total knee replacement: a systematic review

Post-operative patient-related risk factors for chronic pain after total knee replacement: a systematic review

Large variation in measures used to assess outcomes of opioid dependence treatment: A systematic review of longitudinal observational studies

Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis

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