Seafood waste: a source for preparation of commercially employable chitin/chitosan materials

Yadav, Monika; Goswami, Priynshi; Paritosh, Kunwar; Kumar, Manish; Pareek, Nidhi; Vivekanand, Vivekanand

doi:10.1186/s40643-019-0243-y

Cited by 369 publications

(215 citation statements)

References 138 publications

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“…For these reasons, polysaccharides are suitable candidates, taking into account their biocompatibility, biodegradability, and relevant mucoadhesive properties. After exerting their role as drug transporters, polysaccharides are easily degraded into well-tolerated molecules by the metabolism [4]. In order to further improve their desirable properties such as drug affinity and mucoadhesivity, it is possible to modulate the physical and chemical properties of polysaccharides by modification of the constituent glycosidic units.…”

Section: Introductionmentioning

confidence: 99%

Improvement of Peptide Affinity and Stability by Complexing to Cyclodextrin-Grafted Ammonium Chitosan

et al. 2020

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Cyclodextrin-grafted polymers are attractive biomaterials that could bring together the host–guest complexing capability of pristine cyclodextrin and the pharmaceutical features of the polymeric backbone. The present paper is aimed at characterizing the potential application of ammonium–chitosan grafted with 2-methyl-β-cyclodextrin (N+-rCh-MCD) as the functional macromolecular complexing agent for the oral administration of the neuropeptide dalargin (DAL). Specific NMR characterization procedures, along with UV and fluorescence techniques, as well as biological in vitro assessments have been performed. The results indicate that N+-rCh-MCD forms water-soluble complexes with DAL, with a prevalent involvement of Tyr or Phe over Leu and Ala residues. The association constant of DAL with the polymeric derivative is one order of magnitude higher than that with the pristine cyclodextrin (Ka: 2600 M−1 and 120 M−1, respectively). Additionally, N+-rCh-MCD shields DAL from enzymatic degradation in gastrointestinal in vitro models with a three-fold time delay, suggesting a future pharmaceutical exploitation of the polymeric derivative. Therefore, the greater affinity of N+-rCh-MCD for DAL and its protective effect against enzymatic hydrolysis can be attributed to the synergistic cooperation between cyclodextrin and the polymer, which is realized only when the former is covalently linked to the latter.

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Section: Introductionmentioning

confidence: 99%

Improvement of Peptide Affinity and Stability by Complexing to Cyclodextrin-Grafted Ammonium Chitosan

et al. 2020

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“…The molecular formula of chitin is poly (β-(1→4)-N-acetyl-D-glucosamine). The chitin as a polymer is isolated mainly from living organisms (Yadav et al, 2019). It is the second most widespread polimer aster cellulose.…”

Section: Discussionmentioning

confidence: 99%

Development and optimization of the demineralization process for the extraction of chitin from Omani Portunidae segnis

Shaqsi¹,

Hoqani²,

Hossain³

et al. 2020

Preprint

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Background: Chitin is an organic polymer and it is rich marine natural polysaccharide after the cellulose. The main natural sources of chitin are exoskeletons of insects, mollusks, the cell walls of certain fungi and crustaceans such as crabs, shrimps and lobsters. The waste of these marine exoskeletons are pollutant for the environment continuously, but this raw material could be used for the production of commercial chitin. The chitin is an important raw material used for water treatment, agricultural, biomedicinal, biotechnological purposes, food and paper industry and cosmetics. Based on the variety of importance, the present targets of this study is to i. optimize the demineralization process for the removal of calcium and phosphorus from the waste of Portunidae segnis (P. segnis) by using acid at ambient temperature ii. characterize the isolated demineralized sample as well as the percentage of remaining calcium and phosphorus by using Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Results: The coarse powder samples of P. segnis were demineralized with seven different concentrations of hydrochloric acid at ambient temperature for 1 hour. All the demineralization samples at different concentrations were analysed by using sensitive ICP-OES. The results based on ICP-OES showed that among the seven different concentrations wused in the demineralization process for the isolation of chitin, the best was 2M of HCl concentration for the production of chitin. Conclusion: The develop optimized demineralization process could be used commercially for the isolation of chitin for the preparation of agriculture, biomedicine, biotechnological purposes.

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“…As the rate of biodegradation of this material is low because chitin is not soluble in water, this volume accumulates and consequently causing environmental impacts. [45,46].…”

Section: Chitosanmentioning

confidence: 99%

Biodegradable Polymers: Opportunities and Challenges

Rosseto¹,

Rigueto²,

Krein³

et al. 2020

Organic Polymers

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The overuse of polymer materials from fossil sources has generated a large volume of waste that causes environmental impacts due to the degradation time. The technological advance has stimulated the search for alternatives that can contribute to sustainability. In this context, the use of biodegradable polymers, that use raw materials from renewable sources stand out because they have that ability to form films and come from abundant sources. Also, in the expectation of optimizing the environmental benefits in this process, it is possible to value the agroindustrial residues, using them as raw material in the synthesis of the polymer, the physical, chemical and mechanical properties of these polymers are important to evaluate the possible applications. The proposal of this chapter is to present current research on renewable sources, including agricultural and industrial residues, to obtain biodegradable polymers, highlighting their properties and possibilities of application.

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Seafood waste: a source for preparation of commercially employable chitin/chitosan materials

Cited by 369 publications

References 138 publications

Improvement of Peptide Affinity and Stability by Complexing to Cyclodextrin-Grafted Ammonium Chitosan

Improvement of Peptide Affinity and Stability by Complexing to Cyclodextrin-Grafted Ammonium Chitosan

Development and optimization of the demineralization process for the extraction of chitin from Omani Portunidae segnis

Biodegradable Polymers: Opportunities and Challenges

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