Biodegradable Polymers: Opportunities and Challenges

Rosseto, Marieli; Rigueto, César Vinicius Toniciolli; Krein, Daniela D.C.; Balbé, Naiana Pereira; Massuda, Lillian Ávila; Dettmer, Aline

doi:10.5772/intechopen.88146

Cited by 21 publications

(14 citation statements)

References 94 publications

(79 reference statements)

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“…Besides that, the CNP system has also contributed to several other fields of applications such as antimicrobial [106,107], pollutants removal [108], energy resources [109], and catalysis applications [110]. CNPs have been widely utilized in pharmaceutical and biomedicine fields due to their structural flexibility, leading to ease of modifications, conferred controlled release properties, provide protection for active components from degradation and localized retention [21,100,111]. In the pharmaceutical field, various drug delivery applications have been reported, including mucosal delivery, cancer drug delivery, anti-microbial drug delivery, ocular delivery, and vaccine delivery, which demonstrated the outstanding properties of CNPs to aid in the delivery of drugs/therapeutics [60,112].…”

Section: Opportunitiesmentioning

confidence: 99%

Chitosan Nanoparticle-Based System: A New Insight into the Promising Controlled Release System for Lung Cancer Treatment

Kuen

2022

Molecules

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Lung cancer has been recognized as one of the most often diagnosed and perhaps most lethal cancer diseases worldwide. Conventional chemotherapy for lung cancer-related diseases has bumped into various limitations and challenges, including non-targeted drug delivery, short drug retention period, low therapeutic efficacy, and multidrug resistance (MDR). Chitosan (CS), a natural polymer derived from deacetylation of chitin, and comprised of arbitrarily distributed β-(1-4)-linked d-glucosamine (deacetylated unit) and N-acetyl-d-glucosamine (acetylated unit) that exhibits magnificent characteristics, including being mucoadhesive, biodegradable, and biocompatible, has emerged as an essential element for the development of a nano-particulate delivery vehicle. Additionally, the flexibility of CS structure due to the free protonable amino groups in the CS backbone has made it easy for the modification and functionalization of CS to be developed into a nanoparticle system with high adaptability in lung cancer treatment. In this review, the current state of chitosan nanoparticle (CNP) systems, including the advantages, challenges, and opportunities, will be discussed, followed by drug release mechanisms and mathematical kinetic models. Subsequently, various modification routes of CNP for improved and enhanced therapeutic efficacy, as well as other restrictions of conventional drug administration for lung cancer treatment, are covered.

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Section: Opportunitiesmentioning

confidence: 99%

Chitosan Nanoparticle-Based System: A New Insight into the Promising Controlled Release System for Lung Cancer Treatment

Kuen

2022

Molecules

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“…Starch is obtained from plants such as potato, corn, rice, and wheat to produce biopolymers (Mangaraj, Yadav, Bal, Dash, & Mahanti, 2019). Starch is the main constituent in the biopolymers, and it is potentially the most suitable biodegradable polymer for packaging material because of its low cost, availability, and possible extraction from agro-based sources (Rosseto et al, 2019). Among the agricultural wastes, potato peels, wheat, and rice wastes are the most abundant sources of starch (Bertoft, 2017).…”

Section: Starchmentioning

confidence: 99%

Advances in development of biodegradable food packaging material from agricultural and agro‐industry waste

Birania

Kumar

et al. 2021

J Food Process Engineering

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The preferment for farm mechanization and advancement in industrialization has augmented the agro-industrial waste generation. The management of such numerous waste is a challenging and resource-intensive task. The current practices involve releasing this waste into the water bodies and open landfills which causes water, air, and soil pollution. These wastes have the potential to be used as a raw material for the development of value-added products, generation of renewable energy, extraction of food-use compounds, and manufacturing of packaging material. In the current scenario, agro-based materials are captivating the packaging industries toward the development of renewable, biodegradable, and sustainable packaging materials.These agro-based materials have great capability to replace petrochemical-based plastic materials in packaging industries because of their ample availability and biodegradability. Biodegradable packaging materials can be derived from agro-industrial waste either directly or by chemical synthesis or by genetically modified organisms.Agro-based polymers have a scintillating future for a wide range of applications in the food industry and pharmaceuticals, including advances in active and smart packaging with bio-functional characteristics. The present review comprehensively discusses the potential of different agricultural and agro-industrial wastes that can be used for extracting different natural biopolymers and their further use in manufacturing biodegradable food packaging. Practical ApplicationsInformation about the potential agricultural and agro-industrial waste suggests development, optimization, customization, and scale-up of production of biodegradable packaging material to promote its commercial usage. The major patents granted in biodegradable packing, properties of these materials, and the current status of their commercial availability will provide a compiled source of information, start-ups, innovation, research, and future advancements to the industrialists, students, researchers, and entrepreneurs. As an alternative to plastics, biodegradable packaging materials open opportunities for sustainable and environment-friendly solutions to industries and help in fulfilling their corporate social responsibility.

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“…Obtained from the chemical and thermal degradation of collagen, gelatin is also a component of industrial interest because it is a polymer with high biological compatibility [114] and multifunctional properties, improving the elasticity, consistency, and stability of a variety of products [115]. However, gelatin from trivalent chromium-tanned leather residues cannot be applied in food package because the presence of chromium [116].…”

Section: Extraction/recovery Of Compounds Of Industrial And/or Commermentioning

confidence: 99%

Alternative uses for tannery wastes: a review of environmental, sustainability, and science

et al. 2020

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The manufacture of leather covers a wide productive chain and beyond contributes to the economic flow. The various stages of leather processing result in high volumes of solid waste. In Brazil, a daily generation of 375 tons of solid waste is estimated, and landfills are still the most used route to its destination. In this review, emphasis will be given to researches that have sought alternatives for the use of solid waste from the tannery industry. Among the main applications of solid tannery wastes, the following stand out production of adsorbent materials, biodiesel, biogas, biopolymers, applications in agriculture and other applications involving extraction/recovery of compounds of industrial/commercial interest, isolation of microorganisms and production of enzymes and applications in the animal diet. In each alternative of waste application, the technologies used, the opportunities, and the challenges faced are mentioned. We hope that this review can provide valuable information to promote the broad understanding of the possibilities that tannery solid wastes has for the development of biodegradable and agricultural products, wastewater treatment, extraction of compounds of industrial and commercial interest, among others.

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Biodegradable Polymers: Opportunities and Challenges

Cited by 21 publications

References 94 publications

Chitosan Nanoparticle-Based System: A New Insight into the Promising Controlled Release System for Lung Cancer Treatment

Chitosan Nanoparticle-Based System: A New Insight into the Promising Controlled Release System for Lung Cancer Treatment

Advances in development of biodegradable food packaging material from agricultural and agro‐industry waste

Alternative uses for tannery wastes: a review of environmental, sustainability, and science

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