Scrotal Irradiation in Primary Testicular Lymphoma: Review of the Literature and In Silico Planning Comparative Study

Brouwer, Charlotte L.; Wiesendanger, Esther M.; Hulst, P. C. van der; Imhoff, Gustaaf W. van; Langendijk, Johannes A.; Beijert, Max

doi:10.1016/j.ijrobp.2012.06.019

Cited by 9 publications

(9 citation statements)

References 67 publications

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“…As far as radiation techniques are concerned, an article by Brouwer et al evaluated different radiation therapy techniques to treat the scrotum and testicles. Photon irradiation with two oblique beams using wedges resulted in the best coverage per the paper compared to an en-face electron field or opposing radiation fields [13].…”

Section: Discussionmentioning

confidence: 94%

Pediatric Myeloid Sarcoma of the Testes Treated With Surgery and Adjuvant Radiation Therapy

Miller,

Jeberaeel,

Saad

et al. 2024

Cureus

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Myeloid sarcoma (MS) is a rare extramedullary tumor of immature granulocytic cells and is most often associated with acute myeloid leukemia (AML). Myeloid sarcomas can occur anywhere in the body but are seldom present in the testicles, especially in the pediatric population. The treatment of MS, especially testicular myeloid sarcoma (TMS) is not well defined in the literature and the role of radiation therapy in the treatment of TMS is even less well defined. In this case report, we discuss the treatment for TMS in a pediatric patient, review the literature, and discuss the role of radiation therapy in the treatment.

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Section: Discussionmentioning

confidence: 94%

Pediatric Myeloid Sarcoma of the Testes Treated With Surgery and Adjuvant Radiation Therapy

Miller,

Jeberaeel,

Saad

et al. 2024

Cureus

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“…PTL is an uncommon pathological manifestation that only represents 1%-5% of all malignant NHL. It predominantly concerns men over 50 years of age, with a median age of 65 years [3]. Liu et al acknowledged PTL as the most common testicular tumor in the sixth decade of life, comprising 45% of all testicular tumors.…”

Section: Discussionmentioning

confidence: 99%

Imaging Diagnosis of Testicular Lymphoma in Young Male Patient: Incidental Finding in Ultrasonography

Sutrisno

2023

Open Access Maced J Med Sci

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BACKGROUND: Ultrasonography is a common diagnostic procedure in patients with testicular abnormalities. Primary testicular lymphoma (PTL) is rarely discovered and is more common among elderly populations. CASE PRESENTATION: This case describes a young male patient with a history of painless testicular enlargement. Ultrasonography reveals an incidental finding of hypoechoic echo structural mass and increased vascularity using color Doppler ultrasonography. The further pathological examination discovered the findings indicative of a non-Hodgkin, diffuse, and large B-cell lymphoma. These distinctive features should be helpful in suggesting a diagnosis of PTL on imaging. CONCLUSION: PTL is a rare and aggressive extranodal NHL. Despite its low incidence, it is an extremely rare testicular cancer at a young age. Careful ultrasound imaging examination should be applied in patients with testicular enlargement. The presence of hypoechoic echostructural and an increase in vascularity should be considered for the possibility of a diagnosis of primary testicular tumor.

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“…Testicular lymphoma may be the primary and only manifestation of malignant lymphoma, the initial sign of generalized disease, or it may occur during the clinical course of a patient with established lymphoma. Primary Testicular Lymphoma (PTL) concerns mainly men over 50 years of age as shown by most prospective and retrospective studies [13] with a median age of 65 years [14]. Secondary involvement of the testis in patients with lymphoma is far more common than primary testicular lymphoma [15].…”

Section: Discussionmentioning

confidence: 99%

Testicular Burkitt’s Lymphoma: A Case Report and Literature Review

Mekeme,

Fouda,

Abessolo

et al. 2023

OJU

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Background: Burkitt's lymphoma of the testis (TBL) is a rare and extremely aggressive malignant usually diagnosed in front of a testicular mass. We describe an interesting single case of TBL managed by a combined multimodal approach with a review of the literature. Case Report: A patient aged 69-year-old male, newly hypertensive, who presented with a twelve-month history of right testis progressive painful scrotal swelling, which worsens following a motorbike accident. Clinical examination revealed a large tender mass in an erythematous right scrotal bursa. A scrotal ultrasound showed a right heterogenous intra-testicular mass. The patient underwent unilateral (right) radical orchiectomy. Histopathological examination revealed presence of monomorphic lymphoid cells, with moderate to increased size, dissociated inconstantly by macrophages consistent with a Burkitt's-like non-Hodgkin Lymphoma. After surgery, the patient was transferred to oncologist for adjuvant chemotherapy. Conclusion: A testicular mass is a usual circumstance for the discovery of a primary tumour of the testicle. Burkitt's testicular lymphoma is a rare tumour whose diagnosis is based on histological findings. There are non-consensual etiological or predisposing factors. The treatment depends imperatively on the stage of the disease. Therapeutic modalities relay on in surgical excision, chemotherapy and radiation therapy but the accurate procedures are not standardized.

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Scrotal Irradiation in Primary Testicular Lymphoma: Review of the Literature and In Silico Planning Comparative Study

Cited by 9 publications

References 67 publications

Pediatric Myeloid Sarcoma of the Testes Treated With Surgery and Adjuvant Radiation Therapy

Pediatric Myeloid Sarcoma of the Testes Treated With Surgery and Adjuvant Radiation Therapy

Imaging Diagnosis of Testicular Lymphoma in Young Male Patient: Incidental Finding in Ultrasonography

Testicular Burkitt’s Lymphoma: A Case Report and Literature Review

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