Screenning of <i>Chlamydia trachomatis</i> Infection among Women Attending Outpatient Clinic of Infertility

Abstract

Objective: The goal of this study was to determine the prevalence of C. trachomatis in women diagnosed with infertility attending the Outpatient Clinic of Infertility from Botucatu Medical School, UNESP, Brazil. Patients and Methods: This molecular study enrolled a total of 112 women. Among these patients, 62 presented primary infertility while 50 presented secondary infertility. The criteria for eligibility included women who were: reproductive-aged; no prior report of seroconversion for HIV; no antibiotic or vaginal cream used in the preceding 30 days; and abstinence from sexual intercourse for 72 hours before the visit. The women were submitted to a gynecological examination and cervical samples were collected with an endocervical cytobrush for molecular analysis of C. trachomatis. Results: The prevalence of chlamydial infection was 8% with similar prevalence between primary (8.1%) and secondary (8.0%) infertility. Conclusion: Considering the asymptomatic nature of chlamydial infection and its association with tubal factor infertility, there is a pressing need to incorporate the screening of C. trachomatis infection as part of the routine investigation for infertility. The early diagnostic by screening can minimize complications and reduce Public Health costs with Assisted Reproductive Technology.

Study of Chlamydia trachomatis Infection in Infertile Females at a Tertiary Care Hospital in Mumbai, India

“…In a study by Heloisa Lopes Lavorato et al [20] , infertility, the prevalence of chlamydial infection was 8% with similar prevalence between primary (8.1%) and secondary (8.0%) infertility but having no statistical significance between the two groups. In a study reported from Aligarh by Malik A et alin 2006 [9] , the overall chlamydial positivity in the infertile women was found in 31 (28.1%) cases who were positive for one or both chlamydial markers while 1(3.3%) healthy at term control women was found positive for C. trachomatis.…”

Cervicovaginal levels of human beta defensins during bacterial vaginosis

“…trachomatis and N . gonorrhoeae were detected by polymerase chain reaction, as previously described [ 26 , 27 ]. Infection by T .…”

New choreographies of inequalities in reproduction: an overview of assisted reproduction market

“…In this sense, the association between untreated sexually transmitted infections (STIs) in women; and most cases of tubal factor infertility is widely documented ( Ombelet, 2011 ; Paavonen & Eggert-Kruse, 1999 ). Although scarce, some studies investigated the association between Chlamydia trachomatis infection and infertility in Brazil ( Approbato, 2012 ; Lavorato et al ., 2015 ; de Assis et al ., 2021 ). Fernandes et al .…”