Screenings and clusters: a cancer cluster in a chemical plant

Sinks, Thomas

doi:10.1136/oemed-2013-101789

Cited by 2 publications

(2 citation statements)

References 4 publications

(4 reference statements)

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“…This finding may be due to hormonal differences between males and females, such as androgen being more likely to be a risk factor for MM than estrogen (25). Moreover, it may be partly due to the difference in exposure to risk factors between genders, such as smoking, drinking, obesity and occupational exposure, including farming, nuke industry, chemical industry and medical radiation (26). The trends of males notably showed an increasing trend in incidence and mortality rates, whereas females showed a steady trend in incidence rate and even a decreasing trend in mortality rates.…”

Section: Discussionmentioning

confidence: 99%

Secular Trends in the Burden of Multiple Myeloma From 1990 to 2019 and Its Projection Until 2044 in China

Zhao

Niu

et al. 2022

Front. Public Health

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ObjectiveMultiple myeloma (MM) imposes a heavy burden in China. Understanding the secular trend of MM burden and projecting its future trend could facilitate appropriate public health planning and improve the management of MM.MethodsSex-specific incidence and mortality rates of MM in China from 1990 to 2019 were collected from the Global Burden of Disease 2019 study. The secular trend of MM burden was analyzed by joinpoint regression. Age–period–cohort model was used to analyze the effects of age, period, and birth cohort on MM burden and project future trends up to 2044.ResultsFrom 1990 to 2019, the age-standardized incidence and mortality rates of MM continued to increase in males. For females, the age-standardized rates were stable in MM incidence and decreased in MM mortality. Males had a higher disease burden of MM than females. Age effects were the most significant risk factor for MM incidence and mortality. Moreover, the risk of MM incidence and mortality increased with increasing time period but decreased with birth cohort in males and females. The age-standardized incidence and mortality rates of MM in China is predicted to be continuously increasing over the next 25 years.ConclusionThe burden of MM in China is expected to continue to increase in the future, with significant sex difference. A comprehensive understanding of the risk characteristics and disease pattern of MM could help develop timely intervention measures to effectively reduce its burden.

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Section: Discussionmentioning

confidence: 99%

Secular Trends in the Burden of Multiple Myeloma From 1990 to 2019 and Its Projection Until 2044 in China

Zhao

Niu

et al. 2022

Front. Public Health

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“…The SPF’s expert assessment of this cluster was carried out over an eight-year period and was the subject of three reports and two scientific publications in prestigious international peer-reviewed journals (the first one described the incidence of kidney cancer among Adisseo employees compared to the general population, 53 while the second one reported retrospective cohort and case-control studies. 54 As pointed out by an independent scientific commentator, those results “establish[ed] a strong link between workplace exposure from vitamin A synthesis and renal cell carcinoma (RCC).” 55…”

Section: When the Search To Meet Academic Standards In Expertise Complicates The Inclusion Of Field Datamentioning

confidence: 99%

When Scientific Knowledge and Ignorance Make It Difficult to Improve Occupational Health: A French and European Perspective

Counil

Henry

2021

New Solut

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This article analyzes the consequences of the increasing reference to scientific expertise in the decision and implementation process of occupational health policy. Based on examples (exposure limits and attributable fractions) taken from an interdisciplinary seminar conducted in 2014 to 2015 in France, it shows how the measurement or regulation of a problem through biomedicine-based tools produces blind spots. It also uses a case study to show the contradictions between scientific and academic aims and public health intervention. Other indirect implications are also examined, such as the limitation of trade unions’ scope for action. Finally, the article suggests launching a broad political debate accessible to nonspecialists about collective occupational health issues—a dialogue made difficult by the rise of the afore-mentioned techno-scientific perspective.

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Screenings and clusters: a cancer cluster in a chemical plant

Cited by 2 publications

References 4 publications

Secular Trends in the Burden of Multiple Myeloma From 1990 to 2019 and Its Projection Until 2044 in China

Secular Trends in the Burden of Multiple Myeloma From 1990 to 2019 and Its Projection Until 2044 in China

When Scientific Knowledge and Ignorance Make It Difficult to Improve Occupational Health: A French and European Perspective

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