Screening Phytochemical and Anti-Methicillin Resistant (Mrsa) Activity of 70 % Ethanolic Extract From the Stem Bark of Albizia Lebbeck(l.) Benth.(fabaceae)

Abstract

The emergence of multi-drug resistant strains and limitations of present antimicrobial drugs have led to continuous search for natural products as curative agents for Anti-methicillin resistantinfections. The aim of this study was to evaluate antibacterial activity of an ethanolic extract from Albizia lebbeckstem bark against Anti-methicillin resistant. Methods and Results : The methods of dissemination swab on muller-hinton agar and double dilution were used to evaluate the antibacterial activity of 70 % ethanolic extract of stem bark of Albizia lebbeck.All multi-resistant strains of Staphylococcus aureus and the reference strain (ATCC 25923) were sensitive to 70 % ethanolic extract of the stem bark of Albizia lebbeck. The MBCvary from 0,49 mg/mL to 2mg/mL. Also, the phytochemical screening of this extract revealed the presence of Polyphenols, Gallic tannins, Catechin tanninsand Flavonoids. These findings confirm that an 70 % ethanolic extract from Albizia lebbeck stem bark inhibited growth of Anti-methicillin resistant at low concentration and could be utilised as an alternative Anti-methicillin resistantagent.

Phytochemistry and therapeutic uses of Albizia lebbeck

“…The Albizia lebbeck tree has a number of medicinal properties, including those that are antiseptic, antibacterial, anti-fertility, anti-protozoal, anti-dysentric, anti-tubercular, anti-cancer, anxiolytic and anti-convulsant. The gum of Albizia lebbeck is used to treat toothache [3,6] . Various plant parts, including the bark, stems, leaves, roots, fruits, flowers, and seeds, can be used to extract natural fibres [5] .…”