Screening of Free Radical Scavenging Activity of Arogyavardhini Vati

Abstract

Free radicals are the main cause for the pathogenesis of disease. Considering present day’s lifestyle oxidant stress is more on everyone. So anti-oxidants are in much demand worldwide. Only Ayurveda is science of life which has provided a rational basis for such thoughts and active medicines. Arogyavardhini vati is a potent formulation explained in rasashastra for maintaining health. An attempt was made to establish scientific evidence for anti-oxidant property of Arogyvardhini vati. Oxidative stress was induced in albino rats with carbon tetra chloride in all the groups except control. In control group only oxidative stress was induced without drugs. In test group three different concentration of Arogyvardhini vati (10 mg / ml, 20 mg / ml and 50 mg / ml) was administered. In standard group vitamin-c was used. Lipid peroxidation, Glutathione, Catalase Amylase, superoxide dismutase levels were estimated for four days. In an antioxidant assay Arogyvardhini vati 10 mg / ml and 20 mg / ml showed the significant reduction of malondialdehyde concentration and significant improvement in Glutathione, superoxide dismutase, Catalase Amylase activity. Antioxidant activity of Arogyvardhini vati was comparable to that of standard. Arogyvardhini vati demonstrated significant anti-oxidant activity compared to standard and control. This scientific data has given further scope for study in a larger samples and clinical study

A Case Study of Scalp Psoriasis managed with Ayurvedic principles

“…It is having Antiinflammatory, Anti-pruritic and Analgesic properties (12). It also has an outstanding degree of free radical scavenging activity in comparison to vitamin C (13). Mahatiktaka Ghrit has tikta rasa (bitter taste), ushna virya (hot potency) helps in Rasa and Raktaprasadana (improving quality of rasa & rakta) by pacifying vitiated Kapha & Pitta doshas and has rasayana (rejuvenation) properties due to main ingredient amalaki (14).…”