Screening of fermentative bacteria for their ability to bind and biotransform deoxynivalenol, zearalenone and fumonisins in anin vitrosimulated corn silage model

Abstract

Fermentative bacteria can potentially be utilized to detoxify corn silage contaminated by Fusarium toxins. The objective of the present study was to test a large number of these bacteria for their ability to bind and/or biotransform deoxynivalenol (DON), zearalenone (ZEN) and fumonisins B(1) and B(2) (FB(1), FB(2)) in conditions simulating corn silage. A total of 202 strains were screened in contaminated, pH 4, corn infusion inoculated with 5 x 10(8) CFU ml(-1). Eight Lactobacilli and three Leuconostoc biotransformed ZEN into alpha-zearalenol, but no biotransformation was detected for DON and fumonisins. In contrast, most strains were capable of binding Fusarium toxins. The most effective genera were Streptococcus and Enterococcus, capable of binding up to 33, 49, 24 and 62% of DON, ZEN, FB(1) and FB(2), respectively. The ability to bind Fusarium toxins seems to be a common property of fermentative bacteria and could help to decrease their toxicity in animals.

Impact of Pediococcus pentosaceus strain L006 and its metabolites on fumonisin biosynthesis by Fusarium verticillioides

“…Various studies have clearly demonstrated that diverse microorganisms could act as natural antagonists of plant pathogens. Among these microorganisms, lactic acid bacteria that have a long history of use in food and feed and are generally considered as safe organisms have been reported to effectively reduce mould growth and to interact with mycotoxins (El-Nezami, Polychronaki, Salminen, & Mykkanen, 2002;Niderkorn et al, 2006Niderkorn et al, , 2007Niderkorn et al, , 2009). However, little is known regarding the impact of these microorganisms on mycotoxin production and especially Fusarium toxins.…”

In vitro Interaction between Fumonisin B1 and the Intestinal Microflora of Pigs

“…Becker et al (1997) reported that FB 1 was not degraded by Enterococcus faecium while the binding of FB 1 and FB 2 , up to 24 and 62%, respectively by Enterococcus sp. was determined (Niderkorn et al, 2007).…”

The effects of silage feeding on some sensory and health attributes of cow’s milk: A review

“…The ability to bind and/or biotransform the mycotoxins typical for maize silage was tested in 202 bacterial strains (Niderkorn, Morgavi, Pujos, Tissandier, & Boudra, 2007). Several Lactobacillus and Leuconostoc species biotransformed zearalenone into a-zearalenol, but deoxynivalenol and fumonisins B 1 and B 2 were not transformed.…”