Screening of biologically important Zn 2+ by a chemosensor with fluorescent turn on - off mechanism

Khan, Tanveer A.; Sheoran, Monika; M, Venkata Nikhil Raj; Jain, Surbhi; Gupta, Diksha; Naik, Sunil G.

doi:10.1016/j.saa.2017.08.017

Cited by 12 publications

(3 citation statements)

References 39 publications

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“…This kind of structure does not have single electron and can be used in the design of off-on PET probe to detect the fluorescence enhancement. Khan et al [1] designed a weakly fluorescent chemosensor (Fig. 3, derived from [1]) and accomplish the detection of Zn 2+ , the detection limit was as low as 2.31×10 -8 M, which showed great sensitivity.…”

Section: Applicationmentioning

confidence: 99%

“…Khan et al [1] designed a weakly fluorescent chemosensor (Fig. 3, derived from [1]) and accomplish the detection of Zn 2+ , the detection limit was as low as 2.31×10 -8 M, which showed great sensitivity. This probe could also suppress the interference of other ions except the Cd 2+ , because all of them did not show any fluorescence enhancement.…”

Section: Applicationmentioning

confidence: 99%

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Molecular interaction-based fluorescence sensing technologies and their application

Yang¹

2022

HSET

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Sensing technology is a cutting-edge technological approach, which makes it much easier to extract information. Molecular interaction is an indispensable part in the sensing technology process, where the chemical, optical and electrical properties of the system change, and it also plays an important role in the information processing and sample detection. However, there are various problems with most of the current sensing technologies, such as low sensitivity, low selectivity, complicated operation, so they cannot be universally used in applications in various fields. By contrast, the high sensitivity of fluorescence detection technology enables the analytes in species could be detected at very low levels. More importantly, it can provide information on the temporal and spatial distribution of the analyzed species without damaging biological samples, which is of great value for studying the physiological functions of these species. This paper introduces three kinds of molecular interaction-based fluorescence sensing technologies and elaborates their principles, applications in recent years, analyzing their merits and demerits respectively, and finally, concluding predecessors’ research and prospecting the future trends of fluorescence sensing technologies. This paper lays the foundation of molecular interaction-based fluorescence sensing technologies and can provide background knowledge, which will offer help to the future research.

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Section: Applicationmentioning

confidence: 99%

Section: Applicationmentioning

confidence: 99%

Molecular interaction-based fluorescence sensing technologies and their application

Yang¹

2022

HSET

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“…The synthesis of fluorescent chemosensors has received considerable attention in recent years . In particular, the investigation of specific sensors for ionic species is of great interest due to their significance for the environment and health . It is well known that metal ions are related to disease and human health, for example zinc, which is an essential trace element for all organisms.…”

Section: Introductionmentioning

confidence: 99%

Turn‐on fluorescent probe for Zn²⁺ ions based on thiazolidine derivative

Bilgiçli

Günsel

et al. 2020

Applied Organom Chemis

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In this study, simple on–off fluorescent/UV–visible (UV–Vis) probes were easily prepared using 2‐(2‐hydroxyphenyl)thiazolidine‐4‐carboxylic acid (Sen‐1) and/or 2‐(2‐hydroxy‐5‐nitrophenyl)thiazolidine‐4‐carboxylic acid (Sen‐2) for fast detection of Zn2+ ions. Their sensing properties towards common metal ions were investigated using UV–Vis and fluorescence spectroscopies. Sen‐1 and Sen‐2 displayed a significant change with the addition of Zn2+ ions in the UV–Vis spectra. The addition of Zn2+ ions induced a 104 nm bathochromic shift for Sen‐1. The binding ratio towards Zn2+ metal ions was determined to be 1:1 by using Job plot analysis and fluorescence spectroscopy. The association constant and free energy (ΔG) of Sen‐1 and Sen‐2 towards Zn2+ ions were calculated by the Benesi–Hildebrand equation. The limit of detection of Sen‐1 towards Zn2+ ions is 3.73 × 10−8 M, which is about 1/100 of the value recommended by the World Health Organization for drinking water. Sen‐1 was successfully applied to detect Zn2+ ions in water samples and the fluorescence test strip was prepared for visual detection of Zn2+ ions. Finally, the quantum chemical parameters of Sen‐1 and Sen‐2, such as highest occupied molecular orbital, lowest unoccupied molecular orbital, and chemical hardness, were investigated by the Becke, three‐parameter, Lee–Yang–Parr, Hartree–Fock, and M062x methods.

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Fluorescent Zn^II Chemosensor Mediated by a 1,8‐Naphthyridine Derivative and It′s Photophysical Properties

et al. 2018

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One of the greatest challenges in using fluorescent chemosensors for highly selective and sensitive transition‐metal ions is finding an efficient and simple method for its synthesis. In this study, a highly efficient fluorescence chemosensor for ZnII was developed from N‐Boc‐L‐proline modified 1,8‐naphthyridine. The fluorescence intensity of the chemosensor was increased significantly only in the presence of ZnII ion which provided a perceived color change for rapid visual sensing, while other metal ions showed fluorescence quenching or little changes. It was worth noting that the chemosensor L distinguished ZnII from CdII commonly having similar properties. The solvent effect and possible bonding mode for fluorescence enhancement have been also discussed. Results of this study indicated that the Boc‐group in l‐proline significantly improved the sensitivity and selectivity for ZnII detection performance, as confirmed by comparison experiments and time dependent‐density functional theory (TD‐DFT) calculations.

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Screening of biologically important Zn 2+ by a chemosensor with fluorescent turn on - off mechanism

Cited by 12 publications

References 39 publications

Molecular interaction-based fluorescence sensing technologies and their application

Molecular interaction-based fluorescence sensing technologies and their application

Turn‐on fluorescent probe for Zn²⁺ ions based on thiazolidine derivative

Fluorescent Zn^II Chemosensor Mediated by a 1,8‐Naphthyridine Derivative and It′s Photophysical Properties

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Screening of biologically important Zn 2+ by a chemosensor with fluorescent turn on - off mechanism

Cited by 12 publications

References 39 publications

Molecular interaction-based fluorescence sensing technologies and their application

Molecular interaction-based fluorescence sensing technologies and their application

Turn‐on fluorescent probe for Zn2+ ions based on thiazolidine derivative

Fluorescent ZnII Chemosensor Mediated by a 1,8‐Naphthyridine Derivative and It′s Photophysical Properties

Contact Info

Product

Resources

About

Turn‐on fluorescent probe for Zn²⁺ ions based on thiazolidine derivative

Fluorescent Zn^II Chemosensor Mediated by a 1,8‐Naphthyridine Derivative and It′s Photophysical Properties