Screening of amniotic fluid metabolites by gas chromatography-mass spectrometry

Antoshechkin, A.G.; Golovkin, A.B.; Maximova, L.A.; Bakharev, V A

doi:10.1016/s0378-4347(00)82913-8

Cited by 11 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fetal breathing movements induce a displacement of fluid in the nasal airways so that the amniotic fluid in contact with the chemoreceptors is continually renewed (between G weeks 22-40) [31]. Second, the amniotic chemical ecology consists of a large variety of odors originating from fetal and maternal sources [12,32,33]. Fetal pulmonary and urinary fluids increasingly affect the composition of amniotic fluid as gestation advances.…”

Section: Chemosensory Ontogenymentioning

confidence: 99%

Olfaction in the fetal and premature infant: functional status and clinical implications

Schaal

Hummel²,

Soussignan

2004

Clinics in Perinatology

155

103

View full text Add to dashboard Cite

Section: Chemosensory Ontogenymentioning

confidence: 99%

Olfaction in the fetal and premature infant: functional status and clinical implications

Schaal

Hummel²,

Soussignan

2004

Clinics in Perinatology

155

103

View full text Add to dashboard Cite

“…In contrast, metabolites in human amniotic fluids have been investigated for medical purposes such as disease diagnosis. In almost all cases using gas chromatography with mass spectroscopy (GC-MS) for chemical analyses, amniotic fluid samples were pre-treated to stabilize volatile metabolites, to enable analysis of both volatile and nonvolatile substances together by the GC-MS system 33–35 . However, such analyses using liquid samples confound volatile odor components with nonvolatile water-soluble components.…”

Section: Introductionmentioning

confidence: 99%

Sampling, identification and sensory evaluation of odors of a newborn baby’s head and amniotic fluid

Uebi

Hariyama

Suzuki

et al. 2019

Sci Rep

View full text Add to dashboard Cite

For baby odor analyses, noninvasive, stress-free sample collection is important. Using a simple method, we succeeded in obtaining fresh odors from the head of five newborn babies. These odors were chemically analyzed by two-dimensional gas chromatography coupled with mass spectrometry (GC × GC-MS), and compared with each other or with the odor of amniotic fluid from the baby’s mother. We identified 31 chemical components of the volatile odors from neonate heads and 21 from amniotic fluid. Although 15 of these components were common to both sources, there was an apparent difference in the GC × GC patterns between the head and amniotic fluid odors, so the neonate head odor might be individually distinct immediately after birth. Therefore, we made artificial mixtures of the major odor components of the neonate head and maternal amniotic fluid, and used psychological tests to examine whether or not these odors could be distinguished from each other. Our data show that the artificial odor of a neonate head could be distinguished from that of amniotic fluid, and that the odors of artificial head odor mixtures could be correctly discriminated for neonates within an hour after birth and at 2 or 3 days of age.

show abstract

“…Indeed, maternal fluids such as amniotic fluid, colostrum, or milk in mammals, and more generally the maternal body itself, generate or carry a large number of odorants (Antoshechkin et al, 1989; Schaal, 2010). Very young organisms have an urgent need to respond to some of these odors to rapidly interact with the mother; to localize the nipples and suck; and to expand their knowledge about the surroundings.…”

Section: Implications Of Odor Mixture Processing On Behaviormentioning

confidence: 99%

“…The chemical environment is complex not only for adult organisms but also for young, neonates, fetuses, and embryos, even if it is more limited during earlier periods of development (e.g., when the organism is developing in the maternal body, nests, or eggs). Indeed, maternal fluids such as amniotic fluid, colostrum, or milk in mammals, and more generally the maternal body itself, generate or carry a large number of odorants ( Antoshechkin et al, 1989 ; Schaal, 2010 ). Very young organisms have an urgent need to respond to some of these odors to rapidly interact with the mother; to localize the nipples and suck; and to expand their knowledge about the surroundings.…”

Section: Implications Of Odor Mixture Processing On Behaviormentioning

confidence: 99%

The perception of odor objects in everyday life: a review on the processing of odor mixtures

et al. 2014

View full text Add to dashboard Cite

Smelling monomolecular odors hardly ever occurs in everyday life, and the daily functioning of the sense of smell relies primarily on the processing of complex mixtures of volatiles that are present in the environment (e.g., emanating from food or conspecifics). Such processing allows for the instantaneous recognition and categorization of smells and also for the discrimination of odors among others to extract relevant information and to adapt efficiently in different contexts. The neurophysiological mechanisms underpinning this highly efficient analysis of complex mixtures of odorants is beginning to be unraveled and support the idea that olfaction, as vision and audition, relies on odor-objects encoding. This configural processing of odor mixtures, which is empirically subject to important applications in our societies (e.g., the art of perfumers, flavorists, and wine makers), has been scientifically studied only during the last decades. This processing depends on many individual factors, among which are the developmental stage, lifestyle, physiological and mood state, and cognitive skills; this processing also presents striking similarities between species. The present review gathers the recent findings, as observed in animals, healthy subjects, and/or individuals with affective disorders, supporting the perception of complex odor stimuli as odor objects. It also discusses peripheral to central processing, and cognitive and behavioral significance. Finally, this review highlights that the study of odor mixtures is an original window allowing for the investigation of daily olfaction and emphasizes the need for knowledge about the underlying biological processes, which appear to be crucial for our representation and adaptation to the chemical environment.

show abstract

Screening of amniotic fluid metabolites by gas chromatography-mass spectrometry

Cited by 11 publications

References 5 publications

Olfaction in the fetal and premature infant: functional status and clinical implications

Olfaction in the fetal and premature infant: functional status and clinical implications

Sampling, identification and sensory evaluation of odors of a newborn baby’s head and amniotic fluid

The perception of odor objects in everyday life: a review on the processing of odor mixtures

Contact Info

Product

Resources

About