Screening for Adult ADHD in Patients with Fibromyalgia Syndrome

Rensburg, R Van; Meyer, Helgard Pieter; Hitchcock, Sonia Anne; Schuler, Christian Edward

doi:10.1093/pm/pnx275

Cited by 36 publications

(18 citation statements)

References 43 publications

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“…As expected, FM patients exhibited greater levels of childhood and adult ADHD symptoms compared with healthy controls. Higher incidence of both childhood and adult ADHD symptoms in patients with fibromyalgia in this study is in line with previous data (Golimstok, Fernandez, & Garcia Basalo, 2015;Reyero et al, 2011;Van Rensburg, Meyer, Hitchcock, & Schuler, 2017). A recent study demonstrates this symptom-based comorbidity at the clinical level as well (Yılmaz, & Tamam, 2018).…”

Section: Discussionsupporting

confidence: 92%

“…In an earlier small study, patients with fibromyalgia were reported to have higher rates of ADHD symptoms both in adulthood and in childhood when compared to other pain disorder groups (Krause, Krause, Magyarosy, Ernst, & Pongratz, 1998). In a recent study, possible diagnosis of ADHD assessed by Adult ADHD Self-Report Scale in patients with fibromyalgia was more prevalent than the control group and possible ADHD comorbidity was shown to have a significant impact on disease severity (Van Rensburg, Meyer, Hitchcock, & Schuler, 2017). Childhood ADHD symptoms were also found to be more common in patients with fibromyalgia than healthy controls (Reyero et al, 2011).…”

Section: Introductionmentioning

confidence: 95%

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Childhood and adult attention deficit hyperactivity disorder symptoms in fibromyalgia: associations with depression, anxiety and disease impact

Karaş

Çetingök

İlişer³

et al. 2020

International Journal of Psychiatry in Clinical Practice

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Objective:The first aim of this study was to determine the prevalence of childhood and current attention deficit hyperactivity disorder (ADHD) symptoms in patients with fibromyalgia. The second aim is to assess the role of depression and anxiety on the relationship between childhood and adult ADHD symptoms with disease impact in this population.Methods: 64 patients with fibromyalgia were compared to matched 58 healthy controls. All participants completed the Wender Utah Rating Scale (WURS), Adult ADHD Self-Report Scale (ASRS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Fibromyalgia Impact Questionnaire (FIQ).Results: Patients with fibromyalgia had significantly higher mean scores of depression (BDI), anxiety (BAI), childhood ADHD symptoms (WURS), and adult ADHD symptoms (ASRS total, ASRS hyperactivity/impulsivity subscale and ASRS attention deficit subscale) than the control group. Fibromyalgia impact (FIQ) was significantly correlated with depression (BDI) (r=0.57, p<.001), anxiety (BAI) (r=0.56, p<.001) and childhood ADHD symptoms (WURS) (r=0.41, p<.001) in fibromyalgia group. There was no significant correlation between fibromyalgia impact (FIQ) and adult ADHD symptoms (ASRS total or sub-scale scores). Hierarchical multiple regression indicated that childhood ADHD symptoms (WURS), anxiety (BAI) and depression (BDI) predicted fibromyalgia impact. Both anxiety (BAI) and depression (BDI) mediated the relationship between childhood ADHD symptoms (WURS) and fibromyalgia impact (FIQ). Conclusion:Childhood ADHD symptoms may be a contributory factor to poorer functioning in the patients with fibromyalgia. The relationship was more pronounced in the presence of depression and anxiety symptoms. Evaluation of childhood and adult ADHD symptoms in patients with fibromyalgia is important for recognition and treatment of ADHD comorbidity and also for attenuating the severity of the disease.

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 95%

Childhood and adult attention deficit hyperactivity disorder symptoms in fibromyalgia: associations with depression, anxiety and disease impact

Karaş

Çetingök

İlişer³

et al. 2020

International Journal of Psychiatry in Clinical Practice

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“…Paying attention to ADHD in the treatment of fibromyalgia may deliver desirable clinical outcomes. 42 …”

Section: Discussionmentioning

confidence: 99%

Attention-deficit hyperactivity disorder and impulsivity in female patients with fibromyalgia

Yılmaz¹,

Tamam

2018

NDT

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ObjectiveData which indicate a greater role of the central nervous system in the etiology of fibromyalgia are increasing. The goal of the present study is to determine the link between fibromyalgia and attention-deficit hyperactivity disorder (ADHD) and, in addition, to reveal the relevance of impulsivity dimension.MethodsThe study included 78 females with fibromyalgia who applied to a physical medicine and rehabilitation polyclinic in Ceyhan State Hospital and 54 healthy females. The diagnosis of fibromyalgia was made by an experienced specialist of physical medicine and rehabilitation based on the American Rheumatology Association Diagnostic Criteria (2010). The diagnosis of ADHD was by an experienced psychiatrist using Diagnostic and Statistical Manual of Mental Disorders-5. The following inventories were used: adult ADHD self-report scale, Wender Utah rating scale, and Barratt impulsivity scale short form.ResultsAdult ADHD was detected in 29.5% of the fibromyalgia group and 7.4% of the control group; childhood and adolescent attention hyperactivity disorder ratios in these groups were 33.3% and 11.1%, respectively. The differences were statistically significant (P=0.002, P=0.003). Scores of the fibromyalgia group on the Wender Utah rating scale, adult ADHD self-report scale, attention subscale, hyperactivity–impulsivity subscale, and the Barratt impulsivity scale for non-planning and attentional impulsivity were found to be significantly higher than the control group (P<0.05, P<0.01, P<0.01, P<0.05, P<0.01, P<0.05, respectively).ConclusionThe present study has shown that both adult and childhood ADHD are quite common in female fibromyalgia patients. There was a link between fibromyalgia and impulsivity. Certain subtypes of fibromyalgia and attention-deficit hyperactivity deficit disorder could be sharing the common etiological pathways.

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“…These changes were not observed in the women with FM between the ST and the DT conditions. This could be derived from the attention deficit disorder ( van Rensburg et al, 2018 ; Yilmaz and Tamam, 2018 ), which is common in this population. Besides, people with FM usually showed depression or cognitive impairment ( Wolfe et al, 2010 ) in several domains such as long-term memory ( Canovas et al, 2009 ), short-term memory ( Park et al, 2001 ), or working memory ( Coppieters et al, 2015 ).…”

Section: Discussionmentioning

confidence: 99%

“…We hypothesized that DT would engage brain areas related to executive function (prefrontal cortex) ( Ford et al, 2002 ; Giraud et al, 2007 ) and areas related to sensorimotor integration (sensorimotor cortex and posterior parietal cortex) ( Sipp et al, 2013 ; Beurskens et al, 2016 ; Bradford et al, 2016 ). Moreover, neurophysiological differences between healthy controls and people with FM could emerge since people with FM reported an attention deficit disorder ( van Rensburg et al, 2018 ; Yilmaz and Tamam, 2018 ). This is because people with FM have impaired the ability to perform two simultaneous tasks ( Huijnen et al, 2015 ; Villafaina et al, 2018 , 2019d ).…”

Section: Introductionmentioning

confidence: 99%

Neurophysiological Differences Between Women With Fibromyalgia and Healthy Controls During Dual Task: A Pilot Study

Villafaina¹,

Fuentes-García²,

Cano-Plasencia³

et al. 2020

Front. Psychol.

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Background Women with FM have a reduced ability to perform two simultaneous tasks. However, the impact of dual task (DT) on the neurophysiological response of women with FM has not been studied. Objective To explore both the neurophysiological response and physical performance of women with FM and healthy controls while performing a DT (motor–cognitive). Design Cross-sectional study. Methods A total of 17 women with FM and 19 age- and sex-matched healthy controls (1:1 ratio) were recruited. The electroencephalographic (EEG) activity was recorded while participants performed two simultaneous tasks: a motor (30 seconds arm-curl test) and a cognitive (remembering three unrelated words). Theta (4–7 Hz), alpha (8–12 Hz), and beta (13–30) frequency bands were analyzed by using EEGLAB. Results Significant differences were obtained in the healthy control group between single task (ST) and DT in the theta, alpha, and beta frequency bands ( p -value < 0.05). Neurophysiological differences between ST and DT were not found in women with FM. In addition, between-group differences were found in the alpha and beta frequency bands between healthy and FM groups, with lower values of beta and alpha in the FM group. Therefore, significant group ∗ condition interactions were detected in the alpha and beta frequency bands. Regarding physical condition performance, between groups, analyses showed that women with FM obtained significantly worse results in the arm curl test than healthy controls, in both ST and DT. Conclusion Women with FM showed the same electrical brain activity pattern during ST and DT conditions, whereas healthy controls seem to adapt their brain activity to task commitment. This is the first study that investigates the neurophysiological response of women with FM while simultaneously performing a motor and a cognitive task.

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Screening for Adult ADHD in Patients with Fibromyalgia Syndrome

Abstract: These results indicate that the co-occurrence of adult ADHD in FMS may be highly prevalent and may also significantly impact the morbidity of FMS. Patients with FMS should be assessed for the presence of adult ADHD.

Cited by 36 publications

References 43 publications

Childhood and adult attention deficit hyperactivity disorder symptoms in fibromyalgia: associations with depression, anxiety and disease impact

Childhood and adult attention deficit hyperactivity disorder symptoms in fibromyalgia: associations with depression, anxiety and disease impact

Attention-deficit hyperactivity disorder and impulsivity in female patients with fibromyalgia

Neurophysiological Differences Between Women With Fibromyalgia and Healthy Controls During Dual Task: A Pilot Study

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