Screening determination of pharmaceutical pollutants in different water matrices using dual-channel capillary electrophoresis coupled with contactless conductivity detection

Contactless conductivity detection for analytical techniques: Developments from 2016 to 2018

“…Five acidic drugs, including two commonly used painkillers (ibuprofen and diclofenac), were determined concurrently with three basic drugs using a portable CE‐C 4 D with dual‐channel architecture in various water matrices . Portable dual‐channel CE‐C 4 D with a thermostatted separation compartment was applied in the determination of inorganic anions and inorganic cations/heavy metal cations at a remote mining site in Argentina.…”

“…In environmental science, the portability of analytical instrumentation is of key importance since it enables direct on‐site analyses and minimizes possible loss of analytical information due to the transport of samples to laboratory and their delayed analyses. Several portable CE‐C 4 D systems were reported for environmental analyses of small ionic analytes by Hauser and coworkers and Mai and coworkers in the reviewed period.…”

Screening bioactive compounds from natural product and its preparations using capillary electrophoresis

“…There are several major components including two metal electrodes, which are actuator electrode and pick‐up electrode in C4D . Someone applied C4D or its modified structure for detection anti‐oxidative histidine dipeptides in poultry , meldonium in urine as well as pharmaceutical pollutants in water matrices . The device of such detector is quite simple and low‐cost.…”

Application of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE‐C4D): An update

“…A dual‐channel CE‐C 4 D instrument for the determination of various pharmaceutical pollutants was used. Analysis of acidic drugs such as ibuprofen, diclofenac, bezafibrate, ketoprofen and mefenamic acid was performed using the first channel, whereas three basic drugs, namely diphenhydramine, metoprolol and atenolol, were determined with the second channel (Le et al, ). The LODs were in the range of 0.2–0.8 mg L −1 without sample pre‐concentration.…”