Screen Printed Graphene Oxide Textile Biosensor for Applications in Inexpensive and Wearable Point-of-Exposure Detection of Influenza for At-Risk Populations

Kinnamon, David; Krishnan, Siddharth; Brosler, Samantha; Sun, Evan; Prasad, Shalini

doi:10.1149/2.0131808jes

Cited by 71 publications

(58 citation statements)

References 17 publications

(17 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our lab is equipped to address the needs of COVID-19 diagnostics because of our expertise in developing biosensors toward identifying relevant biomarkers from various body fluids such as blood [ 37 ], sweat [ 38 , 39 ], saliva, blood and exhaled breath condensate. For example, robust sensing platforms include a rapid electrochemical device using a single drop of sample (<40 μl blood) for point-of-use parathyroid hormone screening, a portable biosensor for cortisol monitoring in a low volume (1–5 μl) of human sweat and a screen-printed graphene oxide textile biosensor for point-of-exposure detection of influenza for at-risk populations [ 40 ]. The ability to integrate these sensors into wearable material such as face masks and textiles would enable detection of exposure to SARS-CoV-2 virus before symptoms manifest; this would be particularly useful in the incubation phase for asymptomatic carriers.…”

Section: Discussion and Future Perspectivementioning

confidence: 99%

Evidence-Based Point-of-care Technology Development During the COVID-19 Pandemic

et al. 2020

Self Cite

View full text Add to dashboard Cite

Since December 2019, the SARS-CoV-2 outbreak that began in Wuhan, China has spread to nearly every continent and become a global health concern. Although much has been discovered about COVID-19 and its pathogenesis, the WHO has identified an immediate need to increase the levels of testing for COVID-19 and identify the stages of the disease accurately for appropriate action to be taken by clinicians and emergency care units. Harnessing technology for accurate diagnosis and staging will improve patient outcomes and minimize serious consequences of false-positive test results. Point-of-care technologies aim to intervene at every stage of the disease to quickly identify infected patients and asymptomatic carriers and stratify them for timely treatment. This requires the tests to be rapid, accurate, sensitive, simple to use and compatible with many body fluids. Mobile platforms are optimal for remote, small-scale deployment, whereas facility-based platforms at hospital centers and laboratory settings offer higher throughput. Here we review evidence-based point-of-care technologies in the context of the entire continuum of COVID-19, from early screening to treatment, and discuss their impact on improving patient outcomes.

show abstract

Section: Discussion and Future Perspectivementioning

confidence: 99%

Evidence-Based Point-of-care Technology Development During the COVID-19 Pandemic

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Graphene has relevant applications in electronic, optical, and thermoelectric devices including transparent and flexible conductors, electrical and optical sensors. In 2018, Kinnamon and colleagues developed a textile screen-printed biosensor based on a GO transduction film for the detection of environmental exposure to influenza A virus H1N1 [35].…”

Section: Graphene Textiles For Pandemic Spread Controlmentioning

confidence: 99%

Can graphene take part in the fight against COVID-19?

2020

View full text Add to dashboard Cite

The pneumonia outbreak of coronavirus disease 2019 (COVID-19) represents a global issue. The bidimensional material graphene has captured much attention due to promising antimicrobial applications and has also demonstrated antiviral efficacy. In response to this global outbreak, we summarized the current state of knowledge of graphene and virus interaction as well as possible successful applications to fight COVID-19. Antibody-conjugated graphene sheets can rapidly detect targeted virus proteins and can be useful for large population screening, but also for the development of environmental sensors and filters, given the low cost of graphene materials. Functionalized graphene has demonstrated a good viral capture capacity that, combined with heat or light-mediated inactivation, could be used as a disinfectant. Graphene sensors arrays can be implemented on standard utility textiles and drug efficacy screening. Thanks to its high versatility, we foresee that graphene may have a leading role in the fight against COVID-19.

show abstract

“…For example, fabrics or flexible substrates are attractive to develop modern virus-detection sensors. A recent example using graphene oxide-and textile-based impedometric sensors was demonstrated, as shown in Figure 7A [136]. This example employed the electrochemical impedance spectroscopy (EIS) method to measure the impedance shift when the resistance and capacitance change.…”

Section: Moving Toward Modern Electrochemical Detection Of Virusesmentioning

confidence: 99%

“…(A) Wearable electrochemical biosensor for the detection of influenza virus. Adapted under the terms and conditions of the CC-BY 4.0 from[136], copyright 2018, Kinnamon et al, published by J. Electrochem. Soc.…”

mentioning

confidence: 99%

Applying Nanomaterials to Modern Biomedical Electrochemical Detection of Metabolites, Electrolytes, and Pathogens

2020

View full text Add to dashboard Cite

Personal biosensors and bioelectronics have been demonstrated for use in out-of-clinic biomedical devices. Such modern devices have the potential to transform traditional clinical analysis into a new approach, allowing patients or users to screen their own health or warning of diseases. Researchers aim to explore the opportunities of easy-to-wear and easy-to-carry sensors that would empower users to detect biomarkers, electrolytes, or pathogens at home in a rapid and easy way. This mobility would open the door for early diagnosis and personalized healthcare management to a wide audience. In this review, we focus on the recent progress made in modern electrochemical sensors, which holds promising potential to support point-of-care technologies. Key original research articles covered in this review are mainly experimental reports published from 2018 to 2020. Strategies for the detection of metabolites, ions, and viruses are updated in this article. The relevant challenges and opportunities of applying nanomaterials to support the fabrication of new electrochemical biosensors are also discussed. Finally, perspectives regarding potential benefits and current challenges of the technology are included. The growing area of personal biosensors is expected to push their application closer to a new phase of biomedical advancement.

show abstract

Screen Printed Graphene Oxide Textile Biosensor for Applications in Inexpensive and Wearable Point-of-Exposure Detection of Influenza for At-Risk Populations

Cited by 71 publications

References 17 publications

Evidence-Based Point-of-care Technology Development During the COVID-19 Pandemic

Evidence-Based Point-of-care Technology Development During the COVID-19 Pandemic

Can graphene take part in the fight against COVID-19?

Applying Nanomaterials to Modern Biomedical Electrochemical Detection of Metabolites, Electrolytes, and Pathogens

Contact Info

Product

Resources

About