The urgent need for a virtual lab as a solution to the challenges in implementing biology practicums in high schools is becoming increasingly important with the advancement of technology. In the context of biology learning in high schools, virtual labs offer innovation to overcome obstacles in practicum implementation. This research aims to explore the problems faced by students in biology practicums and seek possible solutions. The main objective is to identify problems and potential solutions in biology practicums for high school students, as well as to assess the feasibility of an inquiry-based virtual laboratory product design to facilitate biology practicums for high school students. The research method used is the Research and Development (R&D) approach, adopting the Borg, Gall & Gall model. The results show that a number of high school teachers face challenges in teaching biology practicums due to the limited practical laboratory facilities in schools. Therefore, through the development of a virtual laboratory product that involves practical activities and considers the issues experienced by students, it is hoped that students will acquire practical skills and conceptual understanding in biology, especially in the coordination system material. The implications of this research are that the development of this virtual laboratory can be a suitable learning resource for practical activities related to the coordination system material in biology learning. The conclusion of this research is that the development of an inquiry-based virtual laboratory is an innovative step that meets the needs of biology learning.