<scp>US</scp> not bright but right method of thyroid volume estimation even in large and substernal extended goitres. Comparison of <scp>US</scp> and three methods of <scp>CT</scp> thyroid evaluation – prospective study

Kaniuka-Jakubowska, Sonia; Piskunowicz, Maciej; Zapaśnik, Adam; Lewczuk, Anna; Kaniuka, Aneta; Mizan-Gross, Krystyna; Kaszubowski, Mariusz; Lass, Piotr; Sworczak, Krzysztof

doi:10.1111/cen.12629

Cited by 10 publications

(18 citation statements)

References 23 publications

(78 reference statements)

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“…U ltrasonography is widely used in clinical practice as the most reliable method to determine the volume (1,2) and structure of the thyroid gland. The volume of the thyroid is influenced by age, gender, body mass index (BMI), lean body mass, iodine intake, and genetic factors (3)(4)(5).…”

Section: Introductionmentioning

confidence: 99%

Ultrasonographic assessment of thyroid volume in oldest-old individuals

Duarte

Araújo

Filho

et al. 2017

Arch. Endocrinol. Metab.

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Objective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area. Subjects and methods: The study included 81 independent elderly individuals aged ≥ 80 years (65 [80.2%] women). We determined these individuals' anthropometric characteristics, body mass index (BMI), and lean body mass, as well as thyroid volume and echogenicity by ultrasonography. Results: We observed that octogenarians and nonagenarians had different profiles of thyroid echogenicity. The volume of the thyroid was smaller in nonagenarians than octogenarians (p = 0.012, r = 0.176), and subjects aged 80-89 years had more often hypoechoic glands than those aged ≥ 90 years (p = 0.01 versus 0.602). Conclusion: The identification of ultrasonographic differences in oldestold individuals will contribute to establishing preclinical markers, such as echogenicity, to identify individuals at risk of developing autoimmune thyroid disease. Future prospective studies should identify if 80-89-year-old individuals with hypoechoic glands progress to hypothyroidism, and if the absence of changes in echogenicity (i.e. a normal thyroid parenchyma) would have a positive impact on longevity among nonagenarians. Arch Endocrinol Metab. 2017;61(3):269-75.

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Section: Introductionmentioning

confidence: 99%

Ultrasonographic assessment of thyroid volume in oldest-old individuals

Duarte

Araújo

Filho

et al. 2017

Arch. Endocrinol. Metab.

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“…Several studies [2–4] have shown that thyroid volume measured by ultrasound is the preferred indicator in epidemiological studies and monitoring of iodine deficiency disorders. Nevertheless, thyroid volume measured by ultrasound needs reliable reference intervals for normal thyroid volume from iodine-sufficient populations.…”

Section: Introductionmentioning

confidence: 99%

Larger Thyroid Volume and Adequate Iodine Nutrition in Chinese Schoolchildren: Local Normative Reference Values Compared with WHO/IGN

Lou

Mao

et al. 2016

International Journal of Endocrinology

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Objective. Thyroid volume measured by ultrasound to define goiter needs reliable local thyroid volume reference from iodine-sufficient populations. The aim of this study is to explore the reference interval for normal thyroid volume in schoolchildren aged 8–10 years from Zhejiang Province, China. Methods. A probability-proportionate-to-size sampling method was applied to select a representative sample of 1213 children aged 8–10 years in Zhejiang Province to detect the thyroid volume, salt iodine, and urine iodine. Results. Median urinary iodine concentration in involved schoolchildren was 178.30 (125.00) μg l−1, with the percentage of samples less than 100 μg l−1 as 12.69% and more than 300 μg l−1 as 15.25%. Thyroid volume was significantly correlated with age and anthropometric measurements independently of each other. The 97th percentile of thyroid volume in our study was larger generally than the new international reference. Conclusions. The iodine nutritional status in Zhejiang Province was at an adequate level. Despite some limitations in this study, we initially established the reference values for thyroid volume in 8–10-year-old schoolchildren in Zhejiang Province, China, as a local reference to be used for monitoring iodine deficiency disorders.

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“…No statistically significant difference was observed between US and CT volumetric evaluation either before the treatment (H = 1.74; p = 0.6291) or afterwards (H = 1.09; p = 0.7786). Additionally, using Bland-Atman plots, we assessed previously that in volumetric thyroid measurements US is a comparable method to CT; therefore, in this study US examination was established as a reference method [9].…”

Section: Resultsmentioning

confidence: 99%

Wole guzowate olbrzymie — ambulatoryjne leczenie radiojodem

Kaniuka-Jakubowska

Lewczuk

Mizan-Gross

et al. 2015

Endokrynologia Polska

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Introduction: 131-I treatment of nodular, especially nontoxic, goitre is still reserved mainly for elderly patients, whose numerous concomitant diseases disqualify them from surgery. Therapy often involves isolation and is available only in selected centres, which may be located far from some patients' places of residence, which is inconvenient for elderly people. The aim of the study was to assess the effectiveness of outpatient fractionated 131-I treatment of patients with large nodular goitres, as well as to evaluate complications and the factors affecting treatment results. Material and methods:The study included 35 patients with a large nodular goitre. Thyroid volume and treatment results were evaluated using US and CT neck examination.

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US not bright but right method of thyroid volume estimation even in large and substernal extended goitres. Comparison of US and three methods of CT thyroid evaluation – prospective study

Abstract: US examination is sufficient for epidemiological studies, radioiodine activity calculation and goitre size assessment in everyday medical practice. Neither initial size of the goitre nor its substernal extension affects US assessment precision.

Cited by 10 publications

References 23 publications

Ultrasonographic assessment of thyroid volume in oldest-old individuals

Ultrasonographic assessment of thyroid volume in oldest-old individuals

Larger Thyroid Volume and Adequate Iodine Nutrition in Chinese Schoolchildren: Local Normative Reference Values Compared with WHO/IGN

Wole guzowate olbrzymie — ambulatoryjne leczenie radiojodem

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