<scp>COVID</scp>
            ‐19 Diagnostics: Current Approach, Challenges, and Technology Adaptation

Bhattacherjee, Prama; Patra, Santanu; Mishra, Abhishek; Das, Trupti; Dewangan, Hemlata; Ghosh, Rajgourab; Shukla, Sudheesh K.; Mishra, Anshuman

doi:10.1002/9783527832521.ch2

Cited by 5 publications

(4 citation statements)

References 39 publications

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“…The availability and accessibility of rapid and cost‐effective diagnostic model facilitate the better public health management. 98 , 99 This roadmap model addresses the need for the development of a sustainable healthcare–industry duo model for quality‐assured COVID‐19 rapid diagnostic testing. 100 The pathway on the roadmap should integrate model referring consultative process that involved multi‐task strategies to access to COVID‐19 diagnostic testing and control.…”

Section: Roadmap For Effective Testing and Disease Diagnosismentioning

confidence: 99%

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Progress in COVID research and developments during pandemic

Shukla¹,

Patra²,

Das

et al. 2022

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The pandemic respiratory disease COVID‐19 has spread over the globe within a small span of time. Generally, there are two important points are being highlighted and considered towards the successful diagnosis and treatment process. The first point includes the reduction of the rate of infections and the next one is the decrease of the death rate. The major threat to public health globally progresses due to the absence of effective medication and widely accepted immunization for the COVID‐19. Whereas, understanding of host susceptibility, clinical features, adaptation of COVID‐19 to new environments, asymptomatic infection is difficult and challenging. Therefore, a rapid and an exact determination of pathogenic viruses play an important role in deciding treatments and preventing pandemic to save the people's lives. It is urgent to fix a standardized diagnostic approach for detecting the COVID‐19. Here, this systematic review describes all the current approaches using for screening and diagnosing the COVID‐19 infectious patient. The renaissance in pathogen due to host adaptability and new region, facing creates several obstacles in diagnosis, drug, and vaccine development process. The study shows that adaptation of accurate and affordable diagnostic tools based on candidate biomarkers using sensor and digital medicine technology can deliver effective diagnosis services at the mass level. Better prospects of public health management rely on diagnosis with high specificity and cost‐effective manner along with multidisciplinary research, specific policy, and technology adaptation. The proposed healthcare model with defined road map represents effective prognosis system.

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Section: Roadmap For Effective Testing and Disease Diagnosismentioning

confidence: 99%

“… 102 , 103 , 104 , 105 Potential inclusion of advanced bio‐ and nanomaterials, tissue engineering and digital technologies make substantial contribution for functional therapeutics and diagnostic devices. 98 , 106 , 107 , 108 , 109 , 110…”

Section: Roadmap For Effective Testing and Disease Diagnosismentioning

confidence: 99%

Progress in COVID research and developments during pandemic

Shukla¹,

Patra²,

Das

et al. 2022

VIEW

Self Cite

View full text Add to dashboard Cite

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“…However, a better understanding of SARS-CoV-2 epidemiology remains an unmet need (Du et al, 2021). One way to address this issue relies on affordable, accurate, rapid, and robust methods for SARS-CoV-2 detection, whose accessibility is still a persistent challenge, especially in countries with minimal clinical laboratory infrastructure (Bhattacherjee et al, 2021). SARS-CoV-2 possesses a positive-sense, single-stranded RNA genome of about 30,000 nucleotides (Hu, Guo, Zhou, & Shi, 2021).…”

Section: Introductionmentioning

confidence: 99%

“…Diagnostic tests for SARS‐CoV‐2 involve the detection of viral antigens or viral RNA. The CDC recommends the use of reverse transcription quantitative polymerase chain reaction (RT‐qPCR) as the “gold standard” for detection of viral RNA in human samples (Bhattacherjee et al., 2021). While RT‐qPCR is reliable and accurate, it still requires specialized equipment, limiting reagents, and highly trained personnel, which may not be readily available in all regions (Bustin & Nolan, 2020; CDC, 2020; Vogels et al., 2020).…”

Section: Introductionmentioning

confidence: 99%

CREST, a Cas13‐Based, Rugged, Equitable, Scalable Testing (CREST) for SARS‐CoV‐2 Detection in Patient Samples

et al. 2022

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The COVID-19 pandemic has taken a devastating human toll worldwide. The development of impactful guidelines and measures for controlling the COVID-19 pandemic requires continuous and widespread testing of suspected cases and their contacts through accurate, accessible, and reliable methods for SARS-CoV-2 detection. Here we describe a CRISPR-Cas13-based method for the detection of SARS-CoV-2. The assay is called CREST (Cas13-based, rugged, equitable, scalable testing), and is specific, sensitive, and highly accessible. As such, CREST may provide a low-cost and dependable alternative for SARS-CoV-2 surveillance.

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