The National Cancer Institute's Small Business Innovation Research Development Center (NCI SBIR) supports the commercialization of novel cancer-related technologies by providing resources to 300-400 small businesses each year. Whereas Federal funding is crucial for the translation of technologies to the clinic, the ma-How to cite this article: Pond MA, Narayanan D, Zhang K, et al. CARE program: NCI and FDA interagency collaborations to support oncology small business entrepreneurs.